| UniProt ID | BUD14_YEAST | |
|---|---|---|
| UniProt AC | P27637 | |
| Protein Name | Bud site selection protein 14 | |
| Gene Name | BUD14 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 709 | |
| Subcellular Localization | ||
| Protein Description | Important for bud site selection. Seems to be a regulatory subunit of the BUD14-GLC7 type-I phosphatase complex. The BUD14-GLC7 complex is necessary to regulate microtubule dynamics at the cortex and may function as a specific activator of the dynein complex.. | |
| Protein Sequence | MSNKEEHVDETSASGVKEVSSIAARHDNGYAPSLITSTSGMDSFQSHALLNDPTLIEDYSDIINNRPTSGSKLTLGNEDSESMGGSVVVTPTSNKSSPFNSKLNILSNAAEKGHDVLRNRDDDKELEEENVEKHMHSNSKRDQRHYKENSSELPDSYDYSDSEFEDNLERRLQEIETDSVDSADKDEVHFSVNNTMNPDVDDFSDGLKYAISEDEDEEENYSDDDDFDRKFQDSGFQGEKDDLEEENDDYQPLSPPRELDPDKLYALYAFNGHDSSHCQLGQDEPCILLNDQDAYWWLVKRITDGKIGFAPAEILETFPERLARLNCWKNENMSSQSVASSDSKDDSISSGNKNQSDAESIIPTPALNGYGKGNKSVSFNDVVGYADRFIDDAIEDTSLDSNDDGGEGNGQSYDDDVDNDKETKVTHRDEYTEAKLNFGKFQDDDTSDVVSDVSFSTSLNTPLNVKKVRRQDNKNESEPKTSSSKDREDDYNANRYVGQEKSEPVDSDYDTDLKKVFEAPRMPFANGMAKSDSQNSLSTIGEFSPSSSEWTNESPSTPIVEESSSIPSSRAIKDISQYIHAKSKIEETTNVENTEGQIQASLGSSGGMANQTDAEQPKEELEKHHSTPEEEKQSTLSLHSSSEEDFYMDEQRAVSSASINSSLSGSRALSNTNMSDPASKPNSLVQHLYAPVFDRMDVLMKQLDEIIRK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSNKEEHVD ------CCCCHHHCC | 57.52 | 22814378 | |
| 2 | Phosphorylation | ------MSNKEEHVD ------CCCCHHHCC | 57.52 | 22369663 | |
| 11 | Phosphorylation | KEEHVDETSASGVKE CHHHCCCCCCCCCHH | 25.73 | 22369663 | |
| 12 | Phosphorylation | EEHVDETSASGVKEV HHHCCCCCCCCCHHH | 20.56 | 22369663 | |
| 14 | Phosphorylation | HVDETSASGVKEVSS HCCCCCCCCCHHHHH | 43.84 | 22369663 | |
| 20 | Phosphorylation | ASGVKEVSSIAARHD CCCCHHHHHHHHHCC | 19.67 | 28889911 | |
| 21 | Phosphorylation | SGVKEVSSIAARHDN CCCHHHHHHHHHCCC | 22.79 | 30377154 | |
| 74 | Phosphorylation | PTSGSKLTLGNEDSE CCCCCCCEECCCCCC | 36.03 | 19823750 | |
| 80 | Phosphorylation | LTLGNEDSESMGGSV CEECCCCCCCCCCCE | 25.95 | 19823750 | |
| 82 | Phosphorylation | LGNEDSESMGGSVVV ECCCCCCCCCCCEEE | 27.03 | 28132839 | |
| 86 | Phosphorylation | DSESMGGSVVVTPTS CCCCCCCCEEECCCC | 13.15 | 19779198 | |
| 90 | Phosphorylation | MGGSVVVTPTSNKSS CCCCEEECCCCCCCC | 14.83 | 19823750 | |
| 92 | Phosphorylation | GSVVVTPTSNKSSPF CCEEECCCCCCCCCC | 35.25 | 19823750 | |
| 93 | Phosphorylation | SVVVTPTSNKSSPFN CEEECCCCCCCCCCC | 43.39 | 29734811 | |
| 96 | Phosphorylation | VTPTSNKSSPFNSKL ECCCCCCCCCCCHHH | 47.71 | 19823750 | |
| 97 | Phosphorylation | TPTSNKSSPFNSKLN CCCCCCCCCCCHHHH | 34.81 | 25752575 | |
| 101 | Phosphorylation | NKSSPFNSKLNILSN CCCCCCCHHHHHHHH | 38.61 | 21440633 | |
| 107 | Phosphorylation | NSKLNILSNAAEKGH CHHHHHHHHHHHHCH | 22.18 | 27017623 | |
| 112 | Acetylation | ILSNAAEKGHDVLRN HHHHHHHHCHHHHHC | 57.74 | 24489116 | |
| 150 | Phosphorylation | QRHYKENSSELPDSY HHHHHHCCCCCCCCC | 26.70 | 22369663 | |
| 151 | Phosphorylation | RHYKENSSELPDSYD HHHHHCCCCCCCCCC | 55.52 | 22369663 | |
| 156 | Phosphorylation | NSSELPDSYDYSDSE CCCCCCCCCCCCCHH | 20.26 | 22369663 | |
| 157 | Phosphorylation | SSELPDSYDYSDSEF CCCCCCCCCCCCHHH | 26.70 | 22369663 | |
| 159 | Phosphorylation | ELPDSYDYSDSEFED CCCCCCCCCCHHHHH | 13.22 | 22369663 | |
| 160 | Phosphorylation | LPDSYDYSDSEFEDN CCCCCCCCCHHHHHH | 31.59 | 22369663 | |
| 162 | Phosphorylation | DSYDYSDSEFEDNLE CCCCCCCHHHHHHHH | 37.94 | 22369663 | |
| 177 | Phosphorylation | RRLQEIETDSVDSAD HHHHHHHCCCCCCCC | 38.96 | 22369663 | |
| 179 | Phosphorylation | LQEIETDSVDSADKD HHHHHCCCCCCCCCC | 34.93 | 22369663 | |
| 182 | Phosphorylation | IETDSVDSADKDEVH HHCCCCCCCCCCCEE | 35.89 | 22369663 | |
| 191 | Phosphorylation | DKDEVHFSVNNTMNP CCCCEEEEECCCCCC | 14.73 | 19779198 | |
| 195 | Phosphorylation | VHFSVNNTMNPDVDD EEEEECCCCCCCHHH | 17.08 | 19795423 | |
| 204 | Phosphorylation | NPDVDDFSDGLKYAI CCCHHHCCCCCCEEC | 37.45 | 28132839 | |
| 209 | Phosphorylation | DFSDGLKYAISEDED HCCCCCCEECCCCCC | 17.76 | 22369663 | |
| 212 | Phosphorylation | DGLKYAISEDEDEEE CCCCEECCCCCCCCC | 30.72 | 22369663 | |
| 221 | Phosphorylation | DEDEEENYSDDDDFD CCCCCCCCCCCCCHH | 19.43 | 24909858 | |
| 222 | Phosphorylation | EDEEENYSDDDDFDR CCCCCCCCCCCCHHH | 46.26 | 22369663 | |
| 234 | Phosphorylation | FDRKFQDSGFQGEKD HHHHHHHCCCCCCCC | 30.62 | 19823750 | |
| 240 | Ubiquitination | DSGFQGEKDDLEEEN HCCCCCCCCCHHHCC | 64.46 | 23749301 | |
| 250 | Phosphorylation | LEEENDDYQPLSPPR HHHCCCCCCCCCCCC | 18.20 | 22369663 | |
| 254 | Phosphorylation | NDDYQPLSPPRELDP CCCCCCCCCCCCCCH | 39.27 | 22369663 | |
| 334 | Phosphorylation | CWKNENMSSQSVASS CCCCCCCCCCCCCCC | 36.49 | 23749301 | |
| 335 | Phosphorylation | WKNENMSSQSVASSD CCCCCCCCCCCCCCC | 18.73 | 27717283 | |
| 337 | Phosphorylation | NENMSSQSVASSDSK CCCCCCCCCCCCCCC | 22.92 | 27717283 | |
| 340 | Phosphorylation | MSSQSVASSDSKDDS CCCCCCCCCCCCCCC | 32.30 | 20377248 | |
| 341 | Phosphorylation | SSQSVASSDSKDDSI CCCCCCCCCCCCCCC | 35.84 | 20377248 | |
| 343 | Phosphorylation | QSVASSDSKDDSISS CCCCCCCCCCCCCCC | 39.67 | 20377248 | |
| 347 | Phosphorylation | SSDSKDDSISSGNKN CCCCCCCCCCCCCCC | 34.21 | 28889911 | |
| 349 | Phosphorylation | DSKDDSISSGNKNQS CCCCCCCCCCCCCHH | 35.82 | 28889911 | |
| 350 | Phosphorylation | SKDDSISSGNKNQSD CCCCCCCCCCCCHHH | 44.72 | 21440633 | |
| 356 | Phosphorylation | SSGNKNQSDAESIIP CCCCCCHHHHHHHCC | 48.45 | 22369663 | |
| 360 | Phosphorylation | KNQSDAESIIPTPAL CCHHHHHHHCCCCCC | 27.78 | 22369663 | |
| 364 | Phosphorylation | DAESIIPTPALNGYG HHHHHCCCCCCCCCC | 15.70 | 25521595 | |
| 370 | Phosphorylation | PTPALNGYGKGNKSV CCCCCCCCCCCCCCC | 18.00 | 22369663 | |
| 376 | Phosphorylation | GYGKGNKSVSFNDVV CCCCCCCCCCHHHHH | 27.30 | 22369663 | |
| 378 | Phosphorylation | GKGNKSVSFNDVVGY CCCCCCCCHHHHHHC | 25.98 | 22369663 | |
| 385 | Phosphorylation | SFNDVVGYADRFIDD CHHHHHHCHHHHHHH | 8.17 | 29688323 | |
| 397 | Phosphorylation | IDDAIEDTSLDSNDD HHHHHHCCCCCCCCC | 20.56 | 22369663 | |
| 398 | Phosphorylation | DDAIEDTSLDSNDDG HHHHHCCCCCCCCCC | 42.36 | 22369663 | |
| 401 | Phosphorylation | IEDTSLDSNDDGGEG HHCCCCCCCCCCCCC | 47.67 | 22369663 | |
| 412 | Phosphorylation | GGEGNGQSYDDDVDN CCCCCCCCCCCCCCC | 31.74 | 22369663 | |
| 413 | Phosphorylation | GEGNGQSYDDDVDND CCCCCCCCCCCCCCC | 18.59 | 22369663 | |
| 446 | Phosphorylation | GKFQDDDTSDVVSDV CCCCCCCCCCCCCEE | 33.55 | 19779198 | |
| 447 | Phosphorylation | KFQDDDTSDVVSDVS CCCCCCCCCCCCEEE | 35.09 | 22369663 | |
| 451 | Phosphorylation | DDTSDVVSDVSFSTS CCCCCCCCEEEEECC | 31.95 | 22369663 | |
| 454 | Phosphorylation | SDVVSDVSFSTSLNT CCCCCEEEEECCCCC | 20.62 | 22369663 | |
| 456 | Phosphorylation | VVSDVSFSTSLNTPL CCCEEEEECCCCCCC | 15.02 | 22369663 | |
| 457 | Phosphorylation | VSDVSFSTSLNTPLN CCEEEEECCCCCCCC | 34.91 | 19779198 | |
| 458 | Phosphorylation | SDVSFSTSLNTPLNV CEEEEECCCCCCCCH | 20.58 | 22369663 | |
| 461 | Phosphorylation | SFSTSLNTPLNVKKV EEECCCCCCCCHHHH | 34.15 | 22369663 | |
| 501 | Acetylation | NRYVGQEKSEPVDSD HHCCCCCCCCCCCCC | 52.83 | 24489116 | |
| 507 | Phosphorylation | EKSEPVDSDYDTDLK CCCCCCCCCCCCCHH | 38.00 | 22369663 | |
| 509 | Phosphorylation | SEPVDSDYDTDLKKV CCCCCCCCCCCHHHH | 25.37 | 22890988 | |
| 511 | Phosphorylation | PVDSDYDTDLKKVFE CCCCCCCCCHHHHHH | 36.68 | 22890988 | |
| 531 | Phosphorylation | FANGMAKSDSQNSLS CCCCCCCCCCCCCCH | 32.72 | 21440633 | |
| 533 | Phosphorylation | NGMAKSDSQNSLSTI CCCCCCCCCCCCHHC | 38.05 | 19779198 | |
| 536 | Phosphorylation | AKSDSQNSLSTIGEF CCCCCCCCCHHCCCC | 18.96 | 21440633 | |
| 538 | Phosphorylation | SDSQNSLSTIGEFSP CCCCCCCHHCCCCCC | 20.14 | 21551504 | |
| 539 | Phosphorylation | DSQNSLSTIGEFSPS CCCCCCHHCCCCCCC | 37.99 | 21551504 | |
| 544 | Phosphorylation | LSTIGEFSPSSSEWT CHHCCCCCCCCCCCC | 21.41 | 21551504 | |
| 557 | Phosphorylation | WTNESPSTPIVEESS CCCCCCCCCCCCCCC | 22.03 | 21551504 | |
| 626 | Phosphorylation | EELEKHHSTPEEEKQ HHHHHHCCCHHHHHH | 45.43 | 27717283 | |
| 627 | Phosphorylation | ELEKHHSTPEEEKQS HHHHHCCCHHHHHHH | 30.29 | 24909858 | |
| 634 | Phosphorylation | TPEEEKQSTLSLHSS CHHHHHHHCCCCCCC | 42.24 | 22369663 | |
| 635 | Phosphorylation | PEEEKQSTLSLHSSS HHHHHHHCCCCCCCC | 20.19 | 22369663 | |
| 637 | Phosphorylation | EEKQSTLSLHSSSEE HHHHHCCCCCCCCHH | 24.91 | 22369663 | |
| 640 | Phosphorylation | QSTLSLHSSSEEDFY HHCCCCCCCCHHHHH | 40.63 | 22369663 | |
| 641 | Phosphorylation | STLSLHSSSEEDFYM HCCCCCCCCHHHHHH | 30.90 | 22369663 | |
| 642 | Phosphorylation | TLSLHSSSEEDFYMD CCCCCCCCHHHHHHC | 48.28 | 22369663 | |
| 647 | Phosphorylation | SSSEEDFYMDEQRAV CCCHHHHHHCHHHHH | 18.91 | 22369663 | |
| 655 | Phosphorylation | MDEQRAVSSASINSS HCHHHHHHHHHHCHH | 21.14 | 22369663 | |
| 656 | Phosphorylation | DEQRAVSSASINSSL CHHHHHHHHHHCHHC | 21.31 | 22369663 | |
| 658 | Phosphorylation | QRAVSSASINSSLSG HHHHHHHHHCHHCCC | 25.01 | 22369663 | |
| 661 | Phosphorylation | VSSASINSSLSGSRA HHHHHHCHHCCCCCC | 30.87 | 22369663 | |
| 662 | Phosphorylation | SSASINSSLSGSRAL HHHHHCHHCCCCCCC | 23.28 | 22369663 | |
| 664 | Phosphorylation | ASINSSLSGSRALSN HHHCHHCCCCCCCCC | 36.35 | 22369663 | |
| 666 | Phosphorylation | INSSLSGSRALSNTN HCHHCCCCCCCCCCC | 15.82 | 22369663 | |
| 670 | Phosphorylation | LSGSRALSNTNMSDP CCCCCCCCCCCCCCC | 40.39 | 22369663 | |
| 672 | Phosphorylation | GSRALSNTNMSDPAS CCCCCCCCCCCCCCC | 28.99 | 22369663 | |
| 675 | Phosphorylation | ALSNTNMSDPASKPN CCCCCCCCCCCCCCC | 42.38 | 22369663 | |
| 679 | Phosphorylation | TNMSDPASKPNSLVQ CCCCCCCCCCCHHHH | 54.77 | 21440633 | |
| 680 | Ubiquitination | NMSDPASKPNSLVQH CCCCCCCCCCHHHHH | 50.77 | 23749301 | |
| 683 | Phosphorylation | DPASKPNSLVQHLYA CCCCCCCHHHHHHHH | 38.14 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BUD14_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BUD14_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BUD14_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-97; SER-160; SER-162;SER-222; SER-360; SER-376; SER-378; SER-398; SER-401; SER-641;SER-642; SER-655; SER-658 AND THR-672, AND MASS SPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-160, AND MASSSPECTROMETRY. | |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-212; SER-222 ANDSER-656, AND MASS SPECTROMETRY. | |
