| UniProt ID | FIT1_YEAST | |
|---|---|---|
| UniProt AC | Q04433 | |
| Protein Name | Facilitator of iron transport 1 | |
| Gene Name | FIT1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 528 | |
| Subcellular Localization |
Secreted, cell wall. Membrane Lipid-anchor, GPI-anchor. Covalently-linked GPI-modified cell wall protein (GPI-CWP). |
|
| Protein Description | Involved in the uptake of non-siderophore sources of iron and the siderophores ferrioxamine B and ferrichrome. Has a role in the retention of iron in the cell wall and periplasmic space.. | |
| Protein Sequence | MKLSSAFVLSAITVAALGESITTTITATKNGHVYTKTVTQDATFVWAGEGAAVTSAVTEASTVAATSAAAETSVAAETSIVEPSTSAQGTSADEGSGSSITTTITATKNGHVYTKTVTQDATFVWTGEGERAPASTVATVETSVAAETSVAEPSTSAQGTSADEGSGSSITTTITATKNGHVYTKTVTQDATFVWTGEGERAPVSTVATVETAASPVTSVAEPSASTDEGSGSSITTTITATKNGHVYTKTVTQDATFVWTGEGERAPASTVATSSISAIEIPSTTEASIVEASSAVETSSAAETSSAVETSSAVETSSAVETSSAAETSSAAETSSAVETSSAVEISSAVETSAVETSSSSSTIETTSVKSLSPTQTSLSSSVQASSPIETSSAAKTSSVVPTFSSTTTENSSNSKSTSAVVASTTTSSESSATIVTPTRIGQAYTESSSRDAQSVRTHESNNWSSSSSASTKMVSSITRVQTTTAGIFTNGKSSTTPQIVNYTGAADSIAAGTGLMGAALAAVIFL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 412 | N-linked_Glycosylation | FSSTTTENSSNSKST CCCCCCCCCCCCCCE | 48.96 | - | |
| 464 | N-linked_Glycosylation | VRTHESNNWSSSSSA HHCCCCCCCCCCCCH | 49.65 | - | |
| 503 | N-linked_Glycosylation | STTPQIVNYTGAADS CCCCEEEECCCCCCH | 30.22 | - | |
| 506 | GPI-anchor | PQIVNYTGAADSIAA CEEEECCCCCCHHHH | 14.38 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FIT1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FIT1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FIT1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PCH2_YEAST | PCH2 | genetic | 20093466 | |
| YB75_YEAST | YBR225W | genetic | 20093466 | |
| IOC3_YEAST | IOC3 | genetic | 20093466 | |
| THIK_YEAST | POT1 | genetic | 20093466 | |
| EFM4_YEAST | EFM4 | genetic | 20093466 | |
| RS27A_YEAST | RPS27A | genetic | 20093466 | |
| MSB4_YEAST | MSB4 | genetic | 20093466 | |
| PCH2_YEAST | PCH2 | genetic | 27708008 | |
| YB75_YEAST | YBR225W | genetic | 27708008 | |
| YD186_YEAST | YDL186W | genetic | 27708008 | |
| DYL1_YEAST | DYN2 | genetic | 27708008 | |
| IOC3_YEAST | IOC3 | genetic | 27708008 | |
| EFM4_YEAST | EFM4 | genetic | 27708008 | |
| THIK_YEAST | POT1 | genetic | 27708008 | |
| URA8_YEAST | URA8 | genetic | 27708008 | |
| MSB4_YEAST | MSB4 | genetic | 27708008 | |
| YP015_YEAST | YPR015C | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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