QDR1_YEAST - dbPTM
QDR1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID QDR1_YEAST
UniProt AC P40475
Protein Name Quinidine resistance protein 1
Gene Name QDR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 563
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Multidrug resistance transporter involved in resistance and adaptation to quinidine and ketoconazole..
Protein Sequence MTKQQTSVMRNASIAKEEREGSDNNNVDRSSSDAISDNDAERSNSHSEIDNESNFDMVPYSRFSHKQKMLLVVQCAFTGFFSTVAGSIYYPVLTIIERKFNITEELANVTIVVYFIFQGVAPSIMGGLADTFGRRPIVLWAILAYFCACIGLACAHNYAQILALRCLQAAGISPVIAINSGIMGDVTTKVERGGYVGLVAGFQVVGTAFGALIGAGLSSKWGWRAIFWFLAIGSGICLVFSTLLMPETKRTLVGNGSVTPRSFLNRSLILHVGSVKKTLHLDDPDPETLEPRTSVDFLAPLKILHIREIDILLSIAGLQFSTWTTHQTALTIVLSKKYNLSVAKIGLCFLPAGISTLTSIISAGRYLNWSYRTRKVKYNRWIKEQELQLMEKYKGDKNKVAELIHSNSHYAFNLVEARLHPAFVTLLLSSIGFTAFGWCISVKTPLAAVLCTSAFASLFSNCILTFSTTLIVDLFPSKASTATGCLNLFRCLLSAIFIAALTKMVEKMRYGGVFTFLSAITSSSSLLLFYLLKNGKQLSFDRIRANDKSAGRSVGKNSEKVST
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
218PhosphorylationALIGAGLSSKWGWRA
HHHHHCCCCCHHHHH		29.0227017623
219PhosphorylationLIGAGLSSKWGWRAI
HHHHCCCCCHHHHHH		37.1527017623
251PhosphorylationLMPETKRTLVGNGSV
HCCCCCCEECCCCCC		27.6128889911
257PhosphorylationRTLVGNGSVTPRSFL
CEECCCCCCCHHHHH		27.1528889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of QDR1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of QDR1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of QDR1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TPS1_YEASTTPS1genetic
20093466
STE50_YEASTSTE50genetic
20093466
BUD31_YEASTBUD31genetic
20093466
KIP3_YEASTKIP3genetic
20093466
DBF2_YEASTDBF2genetic
20093466
PFKA2_YEASTPFK2genetic
20093466
SIN3_YEASTSIN3genetic
20093466
FUMH_YEASTFUM1genetic
20093466
HSP7F_YEASTSSE1genetic
20093466
CALX_YEASTCNE1physical
16093310
PHO88_YEASTPHO88physical
16093310
MKAR_YEASTIFA38physical
16093310
TMN3_YEASTTMN3physical
16093310
MST27_YEASTMST27physical
16093310
POM33_YEASTPOM33physical
16093310
RIM1_YEASTRIM1genetic
27708008
REI1_YEASTREI1genetic
27708008
RV161_YEASTRVS161genetic
27708008
DAL81_YEASTDAL81genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
FUMH_YEASTFUM1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of QDR1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory