WTM2_YEAST - dbPTM
WTM2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WTM2_YEAST
UniProt AC Q12206
Protein Name Transcriptional modulator WTM2
Gene Name WTM2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 467
Subcellular Localization
Protein Description Transcriptional modulator with roles in meiotic regulation and silencing..
Protein Sequence MAKSKSSQGASGARRKPAPSLYQHISSFKPQFSTRVDDVLHFSKTLTWRSEIIPDKSKGTLTTSLLYSQGSDIYEIDTTLPLKTFYDDDDDDDNDDDDEEGNGKTKSAATPNPEYGDAFQDVEGKPLRPKWIYQGETVAKMQYLESSDDSTAIAMSKNGSLAWFRDEIKVPVHIVQEMMGPATRYSSIHSLTRPGSLAVSDFDVSTNMDTVVKSQSNGYEEDSILKIIDNSDRPGDILRTVHVPGTNVAHSVRFFNNHLFASCSDDNILRFWDTRTADKPLWTLSEPKNGRLTSFDSSQVTENLFVTGFSTGVIKLWDARAVQLATTDLTHRQNGEEPIQNEIAKLFHSGGDSVVDILFSQTSATEFVTVGGTGNVYHWDMEYSFSRNDDDNEDEVRVAAPEELQGQCLKFFHTGGTRRSSNQFGKRNTVALHPVINDFVGTVDSDSLVTAYKPFLASDFIGRGYDD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MAKSKSSQGAS
----CCCCCCCCCCC		28.3819823750
6Phosphorylation--MAKSKSSQGASGA
--CCCCCCCCCCCCC		34.6819823750
7Phosphorylation-MAKSKSSQGASGAR
-CCCCCCCCCCCCCC		36.0519823750
11PhosphorylationSKSSQGASGARRKPA
CCCCCCCCCCCCCCC		39.5519823750
45PhosphorylationDVLHFSKTLTWRSEI
HHEEECCCCEEECEE		28.3719795423
47PhosphorylationLHFSKTLTWRSEIIP
EEECCCCEEECEECC		24.8619823750
50PhosphorylationSKTLTWRSEIIPDKS
CCCCEEECEECCCCC		25.3919823750
57PhosphorylationSEIIPDKSKGTLTTS
CEECCCCCCCCEEEE		43.6327017623
107PhosphorylationEGNGKTKSAATPNPE
CCCCCCCCCCCCCCC		28.5029136822
110PhosphorylationGKTKSAATPNPEYGD
CCCCCCCCCCCCCCC		24.2620377248
115PhosphorylationAATPNPEYGDAFQDV
CCCCCCCCCCCCCCC		22.8919779198
147PhosphorylationKMQYLESSDDSTAIA
EEEEEECCCCCEEEE		35.7427017623
186PhosphorylationMGPATRYSSIHSLTR
HCCCCCCCCHHCCCC		21.3719779198
190PhosphorylationTRYSSIHSLTRPGSL
CCCCCHHCCCCCCCE		29.7519779198
196PhosphorylationHSLTRPGSLAVSDFD
HCCCCCCCEEECCEE		18.8130377154
200PhosphorylationRPGSLAVSDFDVSTN
CCCCEEECCEECCCC		27.2719779198
205PhosphorylationAVSDFDVSTNMDTVV
EECCEECCCCCCEEE		18.8630377154
279AcetylationWDTRTADKPLWTLSE
EECCCCCCCCEEECC		39.2824489116
417PhosphorylationKFFHTGGTRRSSNQF
EEEECCCCCCCCCCC		25.0121440633
420PhosphorylationHTGGTRRSSNQFGKR
ECCCCCCCCCCCCCC		30.2828889911
421PhosphorylationTGGTRRSSNQFGKRN
CCCCCCCCCCCCCCC		32.6020377248
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of WTM2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WTM2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WTM2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
WTM1_YEASTWTM1physical
11805837
RUVB1_YEASTRVB1physical
11805837
YO283_YEASTYOR283Wphysical
11805837
RIR2_YEASTRNR2physical
11805837
TCPZ_YEASTCCT6physical
11805837
WTM1_YEASTWTM1physical
9234739
WTM2_YEASTWTM2physical
9234739
RIR2_YEASTRNR2physical
16452505
RIR4_YEASTRNR4physical
16452505
RIR2_YEASTRNR2physical
16432237
RIR4_YEASTRNR4physical
16432237
KA122_YEASTKAP122physical
16432237
WTM2_YEASTWTM2physical
18467557
WTM2_YEASTWTM2physical
18719252
ISW2_YEASTISW2genetic
20959818
GLN3_YEASTGLN3genetic
20959818
IES4_YEASTIES4genetic
20959818
UBP3_YEASTUBP3genetic
20959818
CTK1_YEASTCTK1genetic
21127252
MMS22_YEASTMMS22genetic
21127252
RCK2_YEASTRCK2genetic
21127252
YRR1_YEASTYRR1genetic
21127252
RTG1_YEASTRTG1genetic
21127252
ADR1_YEASTADR1genetic
21127252
WTM2_YEASTWTM2physical
22615397
GPR1_YEASTGPR1genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
YL413_YEASTINA1genetic
27708008
YP089_YEASTYPR089Wgenetic
27708008
YP098_YEASTYPR098Cgenetic
27708008
UBC9_HUMANUBE2Iphysical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WTM2_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-110 AND SER-421, ANDMASS SPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory