YRR1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YRR1_YEAST
• UniProt AC: Q12172
• Protein Name: Zinc finger transcription factor YRR1
• Gene Name: YRR1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 810
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1..
• Protein Sequence: MKRRSDALLGSFQATNVTPPSDNSNSTAGGANGSNSGTPTSTSGKKRNKLIKSCGFCRRRKLRCDQQKPMCSTCISRNLTTCQYAEEFNKNIEKKATYGPYPNADLLKKVEELENKIRILEAEKNTNSSASSMYTSPNFPPLGTSVGRGSTETSSPLPDGVINPYADRYYLQSKHSGRSTLYGPTSMRTQIANSNWGFIEKYKQLWAKVKVERNKWKQNNQKTMCRELGLLDESDWQPDPLIKQICRFLPSYNKALSILDDFFNDGACNEINVILDKAKVRRDFLDYFMPEKEVKAEGDRSIVYILSNPKKNYYKAAVILLILCLKYFHTDVPTPIEKFFTLLKGASTAKVFYIERAQMLILFYYHRETYSFGGDGSDLVNINECLVTTVTTIGLHLNIRETFKEHEVFMGSIESLENVWLMAIFIDYNISCNVGRPLLINKFYLDENQDHCILNSKSKTYEGKLKRYLKLTRPMLLTLYDRDKFPDLKAYSKRIINFVEEELGPLGHYTGENISEEVPLRESRILSMAVGLLLSFYALIHSVLKVRNIESKNNTFQLVLINFSIIVNTTIRCYRIDKALYPEKFEASNPHLPPHMALSMSLTAGLFSKTLVFFCSLIYFKLTLFENGLCLSNDMEVGWSDLTKLTVPLDKDLSLGTAMSLYSSIFDRLFTVGNKELIRTMHRSSQFVIELAIERTYRTILGNVIEFRKLTEETWLAQIKQELDPQSDNPSSEAKIVSDRQRDLSLAVPTPTPSIIPMLPSPGETKNHAKSQSEIIQMLTDEFWANYNSGWEELINQSEFSTLFDDYKDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
155	Phosphorylation	RGSTETSSPLPDGVI CCCCCCCCCCCCCCC	37.56	23749301
578	Acetylation	IRCYRIDKALYPEKF EEEEEECHHHCCHHH	37.61	24489116
727	Phosphorylation	KQELDPQSDNPSSEA HHHCCCCCCCCCHHH	44.75	28889911
761	Phosphorylation	SIIPMLPSPGETKNH CCCCCCCCCCCCCCC	41.39	21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YRR1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YRR1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YRR1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YRR1_YEAST	YRR1	physical	15123673
2AAA_YEAST	TPD3	physical	16554755
2ABA_YEAST	CDC55	physical	16554755
YRR1_YEAST	YRR1	physical	18719252
TOS4_YEAST	TOS4	genetic	21127252
SUM1_YEAST	SUM1	genetic	21127252
PP2C1_YEAST	PTC1	genetic	21127252
CTF8_YEAST	CTF8	genetic	21127252
MED16_YEAST	SIN4	genetic	22137896

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-155, AND MASSSPECTROMETRY.
PubMed: 18407956