PYRX_YEAST - dbPTM
PYRX_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PYRX_YEAST
UniProt AC P30402
Protein Name Orotate phosphoribosyltransferase 2
Gene Name URA10
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 227
Subcellular Localization
Protein Description Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)..
Protein Sequence MSASTTSLEEYQKTFLELGLECKALRFGSFKLNSGRQSPYFFNLSLFNSGKLLANLATAYATAIIQSELKFDVIFGPAYKGIPLAAIVCVKLAEIGGTKFQGIQYAFNRKKVKDHGEGGIIVGASLEDKRVLIIDDVMTAGTAINEAFEIISIAQGRVVGCIVALDRQEVIHESDPERTSATQSVSKRYNVPVLSIVSLTQVVQFMGNRLSPEQKSAIENYRKAYGI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
179PhosphorylationHESDPERTSATQSVS
CCCCCCCCCCCHHHH		22.5022369663
180PhosphorylationESDPERTSATQSVSK
CCCCCCCCCCHHHHH		35.2222369663
182PhosphorylationDPERTSATQSVSKRY
CCCCCCCCHHHHHHC		22.5722369663
184PhosphorylationERTSATQSVSKRYNV
CCCCCCHHHHHHCCC		24.8122369663
186PhosphorylationTSATQSVSKRYNVPV
CCCCHHHHHHCCCCE		19.3622369663
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PYRX_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PYRX_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PYRX_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PYRE_YEASTURA5genetic
18408719
PYRE_YEASTURA5genetic
16941010
RL37A_YEASTRPL37Agenetic
20093466
MNE1_YEASTMNE1genetic
20093466
MGR2_YEASTMGR2genetic
20093466
JID1_YEASTJID1genetic
20093466
MRM2_YEASTMRM2genetic
27708008
MED5_YEASTNUT1genetic
27708008
PEX2_YEASTPEX2genetic
27708008
PTK2_YEASTPTK2genetic
27708008
CBT1_YEASTCBT1genetic
27708008
SWS2_YEASTSWS2genetic
27708008
MNE1_YEASTMNE1genetic
27708008
QCR2_YEASTQCR2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PYRX_YEAST

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Related Literatures of Post-Translational Modification

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