STD1_YEAST - dbPTM
STD1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID STD1_YEAST
UniProt AC Q02794
Protein Name Protein STD1
Gene Name STD1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 444
Subcellular Localization Cell membrane
Peripheral membrane protein . Nucleus .
Protein Description Involved in modulation of glucose-regulated gene expression. Together with MTH1, represses the hexose transporter (HXT) genes in conditions of low glucose. Stimulates the SNF1 kinase by an interaction with the catalytic domain that antagonizes autoinhibition and promotes an active conformation of the kinase..
Protein Sequence MFVSPPPATARNQVLGKRKSKRHDENPKNVQPNADTEMTNSVPSIGFNSNLPHNNQEINTPNHYNLSSNSGNVRSNNNFVTTPPEYADRARIEIIKRLLPTAGTKPMEVNSNTAENANIQHINTPDSQSFVSDHSSSYESSIFSQPSTALTDITTGSSLIDTKTPKFVTEVTLEDALPKTFYDMYSPEVLMSDPANILYNGRPKFTKRELLDWDLNDIRSLLIVEQLRPEWGSQLPTVVTSGINLPQFRLQLLPLSSSDEFIIATLVNSDLYIEANLDRNFKLTSAKYTVASARKRHEEMTGSKEPIMRLSKPEWRNIIENYLLNVAVEAQCRYDFKQKRSEYKRWKLLNSNLKRPDMPPPSLIPHGFKIHDCTNSGSLLKKALMKNLQLKNYKNDAKTLGAGTQKNVVNKVSLTSEERAAIWFQCQTQVYQRLGLDWKPDGMS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
288PhosphorylationFKLTSAKYTVASARK
CEECCCEEEHHHHHH		13.2328889911
292PhosphorylationSAKYTVASARKRHEE
CCEEEHHHHHHHHHH		25.0328889911
369UbiquitinationSLIPHGFKIHDCTNS
CCCCCCEEEECCCCC		43.6617644757
381UbiquitinationTNSGSLLKKALMKNL
CCCCHHHHHHHHHHC		41.0917644757
382UbiquitinationNSGSLLKKALMKNLQ
CCCHHHHHHHHHHCC		46.8817644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseGRR1P24814
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of STD1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of STD1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RGT1_YEASTRGT1physical
14508605
RGT1_YEASTRGT1physical
12220226
SNF1_YEASTSNF1physical
8114728
TBP_YEASTSPT15physical
7667094
SNF1_YEASTSNF1physical
12618390
RTG2_YEASTRTG2physical
10373505
SNF3_YEASTSNF3physical
10373505
RGT1_YEASTRGT1physical
15489524
MTH1_YEASTMTH1genetic
8114728
RGT1_YEASTRGT1physical
11283351
RRP6_YEASTRRP6genetic
20959818
CTI6_YEASTCTI6genetic
20959818
RXT2_YEASTRXT2genetic
20959818
SIN3_YEASTSIN3genetic
20959818
AATC_YEASTAAT2genetic
20959818
STB2_YEASTSTB2genetic
20959818
STP4_YEASTSTP4genetic
20959818
YPT6_YEASTYPT6genetic
20959818
YOL19_YEASTYOL019Wgenetic
20526336
TOR2_YEASTTOR2genetic
20526336
TUP1_YEASTTUP1genetic
23468525
PP4R3_YEASTPSY2physical
24277933
SHG1_YEASTSHG1genetic
27708008
IMG2_YEASTIMG2genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
VPS4_YEASTVPS4genetic
27708008
CG13_YEASTCLN3genetic
27708008
FMT_YEASTFMT1genetic
27708008
HAP3_YEASTHAP3genetic
27708008
C1TM_YEASTMIS1genetic
27708008
NPL4_YEASTNPL4genetic
27708008
ODPB_YEASTPDB1genetic
27708008
STE50_YEASTSTE50genetic
27708008
RIM1_YEASTRIM1genetic
27708008
MBP1_YEASTMBP1genetic
27708008
ARX1_YEASTARX1genetic
27708008
HNT2_YEASTHNT2genetic
27708008
RV167_YEASTRVS167genetic
27708008
APT2_YEASTAPT2genetic
27708008
SNF1_YEASTSNF1genetic
27708008
ECM32_YEASTECM32genetic
27708008
IES1_YEASTIES1genetic
27708008
ROG3_YEASTROG3genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
FLX1_YEASTFLX1genetic
27708008
MRS3_YEASTMRS3genetic
27708008
DPOD3_YEASTPOL32genetic
27708008
ILM1_YEASTILM1genetic
27708008
SIC1_YEASTSIC1genetic
27708008
CSF1_YEASTCSF1genetic
27708008
BUD6_YEASTBUD6genetic
27708008
FKS1_YEASTFKS1genetic
27708008
RM39_YEASTMRPL39genetic
27708008
RCF1_YEASTRCF1genetic
27708008
AMPD_YEASTAMD1genetic
27708008
NAB6_YEASTNAB6genetic
27708008
MSS1_YEASTMSS1genetic
27708008
EAF7_YEASTEAF7genetic
27708008
ATP23_YEASTATP23genetic
27708008
LIPA_YEASTLIP5genetic
27708008
UBA3_YEASTUBA3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of STD1_YEAST

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Related Literatures of Post-Translational Modification

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