SNF3_YEAST - dbPTM
SNF3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SNF3_YEAST
UniProt AC P10870
Protein Name High-affinity glucose transporter SNF3
Gene Name SNF3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 884
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description High-affinity glucose transporter. Can function as a negative regulator of glucose transport. SNF3 is involved as well in the transport of mannose and fructose. Serves as a sensor that generates an intracellular signal in the presence of low level of glucose. Inhibition of RGT1 by low levels of glucose, and hence induction of HTX2 and HTX4 expression, requires SNF3..
Protein Sequence MDPNSNSSSETLRQEKQGFLDKALQRVKGIALRRNNSNKDHTTDDTTGSIRTPTSLQRQNSDRQSNMTSVFTDDISTIDDNSILFSEPPQKQSMMMSICVGVFVAVGGFLFGYDTGLINSITSMNYVKSHVAPNHDSFTAQQMSILVSFLSLGTFFGALTAPFISDSYGRKPTIIFSTIFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSFLAIGMFFLPESPRYYVLKDKLDEAAKSLSFLRGVPVHDSGLLEELVEIKATYDYEASFGSSNFIDCFISSKSRPKQTLRMFTGIALQAFQQFSGINFIFYYGVNFFNKTGVSNSYLVSFITYAVNVVFNVPGLFFVEFFGRRKVLVVGGVIMTIANFIVAIVGCSLKTVAAAKVMIAFICLFIAAFSATWGGVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYIVDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVYETKGLTLEEIDELYIKSSTGVVSPKFNKDIRERALKFQYDPLQRLEDGKNTFVAKRNNFDDETPRNDFRNTISGEIDHSPNQKEVHSIPERVDIPTSTEILESPNKSSGMTVPVSPSLQDVPIPQTTEPAEIRTKYVDLGNGLGLNTYNRGPPSLSSDSSEDYTEDEIGGPSSQGDQSNRSTMNDINDYMARLIHSTSTASNTTDKFSGNQSTLRYHTASSHSDTTEEDSNLMDLGNGLALNAYNRGPPSILMNSSDEEANGGETSDNLNTAQDLAGMKERMAQFAQSYIDKRGGLEPETQSNILSTSLSVMADTNEHNNEILHSSEENATNQPVNENNDLK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
42PhosphorylationNNSNKDHTTDDTTGS
CCCCCCCCCCCCCCC		41.8930377154
46PhosphorylationKDHTTDDTTGSIRTP
CCCCCCCCCCCCCCC		35.5530377154
303PhosphorylationKLDEAAKSLSFLRGV
HHHHHHHHHHHHHCC		25.2321440633
305PhosphorylationDEAAKSLSFLRGVPV
HHHHHHHHHHHCCCC		29.3521440633
383N-linked_GlycosylationYYGVNFFNKTGVSNS
EEECCCCCCCCCCHH		36.52-
559PhosphorylationIDELYIKSSTGVVSP
HHEEEEECCCCCCCC		24.4728889911
561PhosphorylationELYIKSSTGVVSPKF
EEEEECCCCCCCCCC		40.8828889911
591UbiquitinationLQRLEDGKNTFVAKR
HHHHHCCCCCEEEEC		66.2023749301
597UbiquitinationGKNTFVAKRNNFDDE
CCCCEEEECCCCCCC		50.8123749301
605PhosphorylationRNNFDDETPRNDFRN
CCCCCCCCCCCCCCC		34.2523749301
613PhosphorylationPRNDFRNTISGEIDH
CCCCCCCHHCCCCCC		16.5624961812
615PhosphorylationNDFRNTISGEIDHSP
CCCCCHHCCCCCCCC		28.4723749301
621PhosphorylationISGEIDHSPNQKEVH
HCCCCCCCCCHHHCC		23.0727214570
629PhosphorylationPNQKEVHSIPERVDI
CCHHHCCCCCCCCCC		45.0420377248
638PhosphorylationPERVDIPTSTEILES
CCCCCCCCCCHHHCC		48.9221440633
639PhosphorylationERVDIPTSTEILESP
CCCCCCCCCHHHCCC		20.7721440633
640PhosphorylationRVDIPTSTEILESPN
CCCCCCCCHHHCCCC		29.5324961812
645PhosphorylationTSTEILESPNKSSGM
CCCHHHCCCCCCCCC		30.2620377248
678PhosphorylationPAEIRTKYVDLGNGL
CCEEEEEEEECCCCC		9.8928889911
690PhosphorylationNGLGLNTYNRGPPSL
CCCCCCCCCCCCCCC		11.2028889911
720PhosphorylationPSSQGDQSNRSTMND
CCCCCCCCCCCHHHH		38.6628889911
724PhosphorylationGDQSNRSTMNDINDY
CCCCCCCHHHHHHHH		19.4328889911
738PhosphorylationYMARLIHSTSTASNT
HHHHHHHHCCCCCCC		19.6322369663
739PhosphorylationMARLIHSTSTASNTT
HHHHHHHCCCCCCCC		18.8823749301
740PhosphorylationARLIHSTSTASNTTD
HHHHHHCCCCCCCCC		25.6222369663
741PhosphorylationRLIHSTSTASNTTDK
HHHHHCCCCCCCCCC		33.9123749301
743PhosphorylationIHSTSTASNTTDKFS
HHHCCCCCCCCCCCC		34.4922369663
745PhosphorylationSTSTASNTTDKFSGN
HCCCCCCCCCCCCCC		33.6022369663
746PhosphorylationTSTASNTTDKFSGNQ
CCCCCCCCCCCCCCC		41.2523749301
797PhosphorylationPPSILMNSSDEEANG
CCCEECCCCCCCCCC		25.7927017623
808PhosphorylationEANGGETSDNLNTAQ
CCCCCCCCCCHHHHH		21.8727017623
821UbiquitinationAQDLAGMKERMAQFA
HHHHHHHHHHHHHHH		41.0522106047
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SNF3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SNF3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SNF3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HXT1_YEASTHXT1genetic
8417358
HXT1_YEASTHXT1genetic
7982576
HXT1_YEASTHXT1genetic
2046678
HXT2_YEASTHXT2genetic
7982576
HXT2_YEASTHXT2genetic
2233722
HXT3_YEASTHXT3genetic
8417358
HXT3_YEASTHXT3genetic
7982576
HXT4_YEASTHXT4genetic
7982576
SKS1_YEASTSKS1genetic
8948096
RGT2_YEASTRGT2genetic
9564039
RTG2_YEASTRTG2genetic
10373505
MTH1_YEASTMTH1genetic
10632886
MTH1_YEASTMTH1genetic
10373505
RGT1_YEASTRGT1genetic
1874412
RGT2_YEASTRGT2genetic
8901598
RGT2_YEASTRGT2genetic
1874412
CYC8_YEASTCYC8genetic
6392017
RGT1_YEASTRGT1genetic
8948096
NOT2_YEASTCDC36genetic
17314980
IRA2_YEASTIRA2genetic
17311585
RGT2_YEASTRGT2genetic
18227642
SKS1_YEASTSKS1genetic
9559544
RGT2_YEASTRGT2genetic
8948096
CYC8_YEASTCYC8genetic
8948096
MTH1_YEASTMTH1genetic
23234240
RGT1_YEASTRGT1genetic
23234240
STD1_YEASTSTD1genetic
23234240
HXT2_YEASTHXT2genetic
23234240
RGT2_YEASTRGT2genetic
25541485
GPR1_YEASTGPR1genetic
25541485
CDC24_YEASTCDC24genetic
27708008
STU1_YEASTSTU1genetic
27708008
CND2_YEASTBRN1genetic
27708008
CALM_YEASTCMD1genetic
27708008
RPAB1_YEASTRPB5genetic
27708008
SEC7_YEASTSEC7genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
BCP1_YEASTBCP1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
CDC20_YEASTCDC20genetic
27708008
MCE1_YEASTCEG1genetic
27708008
SMD1_YEASTSMD1genetic
27708008
IPI1_YEASTIPI1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
NNF1_YEASTNNF1genetic
27708008
CWC16_YEASTYJU2genetic
27708008
SDO1_YEASTSDO1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
TYSY_YEASTCDC21genetic
27708008
BUR1_YEASTSGV1genetic
27708008
ETR1_YEASTETR1genetic
27708008
ODPB_YEASTPDB1genetic
27708008
NKP1_YEASTNKP1genetic
27708008
SAC7_YEASTSAC7genetic
27708008
CEM1_YEASTCEM1genetic
27708008
VPS55_YEASTVPS55genetic
27708008
VPS51_YEASTVPS51genetic
27708008
SAM37_YEASTSAM37genetic
27708008
COX7_YEASTCOX7genetic
27708008
VPS17_YEASTVPS17genetic
27708008
RGT2_YEASTRGT2genetic
28790206
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SNF3_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-720 AND THR-724, ANDMASS SPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory