HNT2_YEAST - dbPTM
HNT2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HNT2_YEAST
UniProt AC P49775
Protein Name Bis(5'-adenosyl)-triphosphatase
Gene Name HNT2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 206
Subcellular Localization Cytoplasm. Nucleus. Mitochondrion.
Protein Description Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock..
Protein Sequence MNKPIYFSKFLVTEQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINNVGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MNKPIYFSKFL
----CCCCEEEEEEE		22.8521126336
150PhosphorylationRQARKNNSTSATVDG
CHHCCCCCCCCEECH		32.8827017623
154PhosphorylationKNNSTSATVDGDELS
CCCCCCCEECHHHHC		20.9227017623
168AcetylationSQGPNVLKPDSQRKV
CCCCCCCCCCHHHHH		42.3624489116
171PhosphorylationPNVLKPDSQRKVRAL
CCCCCCCHHHHHHHH		40.1727017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HNT2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HNT2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HNT2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HNT2_YEASTHNT2physical
18467557
ECM33_YEASTECM33genetic
20093466
GDIR_YEASTRDI1genetic
20093466
SWF1_YEASTSWF1genetic
20093466
HOP1_YEASTHOP1genetic
20093466
UBX6_YEASTUBX6genetic
20093466
MNN4_YEASTMNN4genetic
20093466
APE2_YEASTAPE2genetic
20093466
COX12_YEASTCOX12genetic
20093466
ACE2_YEASTACE2genetic
20093466
YL346_YEASTYLR346Cgenetic
20093466
JLP2_YEASTJLP2genetic
20093466
SCS7_YEASTSCS7genetic
20093466
MED9_YEASTCSE2genetic
20093466
MPD2_YEASTMPD2genetic
20093466
ERG2_YEASTERG2genetic
21623372
ODPB_YEASTPDB1genetic
21623372
ODPA_YEASTPDA1genetic
21623372
PMT5_YEASTPMT5genetic
21623372
LCB2_YEASTLCB2genetic
27708008
STS1_YEASTSTS1genetic
27708008
CDC11_YEASTCDC11genetic
27708008
MVD1_YEASTMVD1genetic
27708008
TYSY_YEASTCDC21genetic
27708008
BUD31_YEASTBUD31genetic
27708008
MEI4_YEASTMEI4genetic
27708008
WWM1_YEASTWWM1genetic
27708008
YJE9_YEASTYJL049Wgenetic
27708008
YL422_YEASTYLR422Wgenetic
27453043
SERB_YEASTSER2genetic
27453043
SNF2_YEASTSNF2genetic
27453043
CDC42_YEASTCDC42genetic
27453043
SWI4_YEASTSWI4genetic
27453043
SWI6_YEASTSWI6genetic
27453043
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HNT2_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory