UBX6_YEAST - dbPTM
UBX6_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBX6_YEAST
UniProt AC P47049
Protein Name UBX domain-containing protein 6
Gene Name UBX6
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 396
Subcellular Localization
Protein Description Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway..
Protein Sequence MYEMSGIDSLFHDRVVHDYSHTSEQVIVVYISSAAGDNSWLHQWFKPGNLSDEERENILWVRLVNGTKECLLFKSIFPSSSAPSINILQNGLLECSIQGNSLSREQDPWETFINGLQSVFKGQVTKRKLFSKSNEEYQRVKRMIQNDKLERKYVFQNTNDPQRKPQKWKQLTVTDNVSYKSQKGFLAQNYCTLQLKLPNGYTISNTFPPQTKLHKVRMWLDYNCYDDGTPYLFHRNIPRVTLTRNDELKSLQELDLLPRSTLILEPLEANNKTFDYMEQSSLLHKVYSGLTSFWAKEPEVDASSSRLGYQRLGTNVSNSANYSLQKLSSLDMVSDGGGGGGGDSMTPSAYTTPRMYPSNGTSQLRQNVSELNLSSNNSASNTKVRTLGYSNNNGNN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5Phosphorylation---MYEMSGIDSLFH
---CCCCCCHHHHHC		22.2128889911
121UbiquitinationNGLQSVFKGQVTKRK
HHHHHHHCCCCCCEE		46.4017644757
152UbiquitinationQNDKLERKYVFQNTN
HCCHHHEEEECCCCC		36.0717644757
164UbiquitinationNTNDPQRKPQKWKQL
CCCCCCCCCCCCCEE		46.7017644757
167UbiquitinationDPQRKPQKWKQLTVT
CCCCCCCCCCEEEEE		65.9617644757
196UbiquitinationNYCTLQLKLPNGYTI
CEEEEEEECCCCEEE		49.2717644757
212UbiquitinationNTFPPQTKLHKVRMW
CCCCCCCCCEEEEEE		43.2617644757
249UbiquitinationLTRNDELKSLQELDL
ECCCHHHHHHHHHCC		47.2617644757
272UbiquitinationEPLEANNKTFDYMEQ
EEHHHCCCCCCHHHH		50.8317644757
285UbiquitinationEQSSLLHKVYSGLTS
HHHHHHHHHHHCCHH		42.7217644757
288PhosphorylationSLLHKVYSGLTSFWA
HHHHHHHHCCHHHHC		30.2521440633
296UbiquitinationGLTSFWAKEPEVDAS
CCHHHHCCCCCCCCC		65.4817644757
348PhosphorylationGGDSMTPSAYTTPRM
CCCCCCCCCCCCCCC		25.4119779198
351PhosphorylationSMTPSAYTTPRMYPS
CCCCCCCCCCCCCCC		30.0028152593
352PhosphorylationMTPSAYTTPRMYPSN
CCCCCCCCCCCCCCC		9.0229734811
369PhosphorylationSQLRQNVSELNLSSN
HHHHHHHHHHCCCCC		43.8722369663
374PhosphorylationNVSELNLSSNNSASN
HHHHHCCCCCCCCCC		29.9122369663
375PhosphorylationVSELNLSSNNSASNT
HHHHCCCCCCCCCCC		43.1022369663
378PhosphorylationLNLSSNNSASNTKVR
HCCCCCCCCCCCEEE		37.0122369663
380PhosphorylationLSSNNSASNTKVRTL
CCCCCCCCCCEEEEE		44.8723749301
382PhosphorylationSNNSASNTKVRTLGY
CCCCCCCCEEEEEEC		28.5522369663
383UbiquitinationNNSASNTKVRTLGYS
CCCCCCCEEEEEECC		33.6923749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBX6_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBX6_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBX6_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SHE2_YEASTSHE2physical
10688190
SHE2_YEASTSHE2physical
11283351
ATG17_YEASTATG17physical
18719252
MFG1_YEASTMFG1genetic
20093466
TMS1_YEASTTMS1genetic
20093466
HNT2_YEASTHNT2genetic
20093466
PALF_YEASTRIM8genetic
20093466
SKI2_YEASTSKI2genetic
20093466
VPS9_YEASTVPS9genetic
20093466
DDC1_YEASTDDC1genetic
20093466
CDC48_YEASTCDC48physical
15258615
RIM1_YEASTRIM1genetic
27708008
BUD31_YEASTBUD31genetic
27708008
NIF3_YEASTNIF3genetic
27708008
ASK10_YEASTASK10genetic
27708008
ILM1_YEASTILM1genetic
27708008
MET5_YEASTMET5genetic
27708008
DGR2_YEASTDGR2genetic
27708008
VPS9_YEASTVPS9genetic
27708008
YMW4_YEASTYMR074Cgenetic
27708008
INO4_YEASTINO4genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBX6_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-369, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory