MNN4_YEAST - dbPTM
MNN4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MNN4_YEAST
UniProt AC P36044
Protein Name Protein MNN4
Gene Name MNN4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1178
Subcellular Localization Membrane
Single-pass type II membrane protein .
Protein Description May function as a positive regulator for mannosylphosphate transferase. Is required to mediate mannosylphosphate transfer in both the core and outer chain portions of N-linked oligosaccharides..
Protein Sequence MLQRISSKLHRRFLSGLLRVKHYPLRRILLPLILLQIIIITFIWSNSPQRNGLGRDADYLLPNYNELDSDDDSWYSILTSSFKNDRKIQFAKTLYENLKFGTNPKWVNEYTLQNDLLSVKMGPRKGSKLESVDELKFYDFDPRLTWSVVLNHLQNNDADQPEKLPFSWYDWTTFHELNKLISIDKTVLPCNFLFQSAFDKESLEAIETELGEPLFLYERPKYAQKLWYKAARNQDRIKDSKELKKHCSKLFTPDGHGSPKGLRFNTQFQIKELYDKVRPEVYQLQARNYILTTQSHPLSISIIESDNSTYQVPLQTEKSKNLVQSGLLQEYINDNINSTNKRKKNKQDVEFNHNRLFQEFVNNDQVNSLYKLEIEETDKFTFDKDLVYLSPSDFKFDASKKIEELEEQKKLYPDKFSAHNENYLNSLKNSVKTSPALQRKFFYEAGAVKQYKGMGFHRDKRFFNVDTLINDKQEYQARLNSMIRTFQKFTKANGIISWLSHGTLYGYLYNGMAFPWDNDFDLQMPIKHLQLLSQYFNQSLILEDPRQGNGRYFLDVSDSLTVRINGNGKNNIDARFIDVDTGLYIDITGLASTSAPSRDYLNSYIEERLQEEHLDINNIPESNGETATLPDKVDDGLVNMATLNITELRDYITSDENKNHKRVPTDTDLKDLLKKELEELPKSKTIENKLNPKQRYFLNEKLKLYNCRNNHFNSFEELSPLINTVFHGVPALIPHRHTYCLHNEYHVPDRYAFDAYKNTAYLPEFRFWFDYDGLKKCSNINSWYPNIPSINSWNPNLLKEISSTKFESKLFDSNKVSEYSFKNLSMDDVRLIYKNIPKAGFIEVFTNLYNSFNVTAYRQKELEIQYCQNLTFIEKKKLLHQLRINVAPKLSSPAKDPFLFGYEKAMWKDLSKSMNQTTLDQVTKIVHEEYVGKIIDLSESLKYRNFSLFNITFDETGTTLDDNTEDYTPANTVEVNPVDFKSNLNFSSNSFLDLNSYGLDLFAPTLSDVNRKGIQMFDKDPIIVYEDYAYAKLLEERKRREKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKQEEEEKKKKEEEEKKKQEEGEKMKNEDEENKKNEDEEKKKNEEEEKKKQEEKNKKNEDEEKKKQEEEEKKKNEEEEKKKQEEGHSN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
911PhosphorylationKAMWKDLSKSMNQTT
HHHHHHHHHHCCCCC		32.5828889911
913PhosphorylationMWKDLSKSMNQTTLD
HHHHHHHHCCCCCHH		21.4227017623
917PhosphorylationLSKSMNQTTLDQVTK
HHHHCCCCCHHHHHH		25.0727017623
930PhosphorylationTKIVHEEYVGKIIDL
HHHHCHHHHHHHHCC		16.1227017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MNN4_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MNN4_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MNN4_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BUD31_YEASTBUD31genetic
20093466
YD186_YEASTYDL186Wgenetic
20093466
CWC15_YEASTCWC15genetic
20093466
HNT2_YEASTHNT2genetic
20093466
PAL1_YEASTPAL1genetic
20093466
RLA4_YEASTRPP2Bgenetic
20093466
MSH4_YEASTMSH4genetic
20093466
LSB3_YEASTLSB3genetic
20093466
ACBP_YEASTACB1genetic
20093466
DRN1_YEASTDRN1genetic
20093466
PCP1_YEASTPCP1genetic
20093466
INM1_YEASTINM1genetic
20093466
RPA34_YEASTRPA34genetic
20093466
GAL80_YEASTGAL80genetic
20093466
FAR3_YEASTFAR3genetic
20093466
RIM13_YEASTRIM13genetic
20093466
ALDH2_YEASTALD2genetic
20093466
ERG2_YEASTERG2genetic
20093466
TRM11_YEASTTRM11genetic
20093466
PHO80_YEASTPHO80genetic
20093466
YME1_YEASTYME1genetic
20093466
YP089_YEASTYPR089Wgenetic
20093466
LEM3_YEASTLEM3genetic
19325107
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MNN4_YEAST

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Related Literatures of Post-Translational Modification

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