dbPTM

DAL80_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DAL80_YEAST
UniProt AC	P26343
Protein Name	Nitrogen regulatory protein DAL80
Gene Name	DAL80
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	269
Subcellular Localization	Nucleus.
Protein Description	Negative regulator of multiple nitrogen catabolic genes including the allantoin pathway genes..
Protein Sequence	MVLSDSLKLPSPTLSAAAGVDDCDGEDHPTCQNCFTVKTPLWRRDEHGTVLCNACGLFLKLHGEPRPISLKTDTIKSRNRKKLNNNNVNTNANTHSNDPNKIFKRKKRLLTTGGGSLPTNNPKVSILEKFMVSGSIKPLLKPKETVPNTKECSTQRGKFSLDPCEPSGKNYLYQINGSDIYTSNIELTRLPNLSTLLEPSPFSDSAVPEIELTWKLHNEEEVIKLKTKISELELVTDLYKKHIFQLNEKCKQLEVELHSRASVQSHPQH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
111	Phosphorylation	KRKKRLLTTGGGSLP HHCCCEEECCCCCCC	28.17	17563356
112	Phosphorylation	RKKRLLTTGGGSLPT HCCCEEECCCCCCCC	33.52	17563356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DAL80_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DAL80_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DAL80_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DAL80_YEAST	DAL80	physical	9791119
GZF3_YEAST	GZF3	physical	9791119
URC2_YEAST	URC2	physical	11283351
URE2_YEAST	URE2	physical	18719252
URC2_YEAST	URC2	physical	18719252
HDA1_YEAST	HDA1	physical	18719252
DAL80_YEAST	DAL80	physical	18719252
BRE5_YEAST	BRE5	genetic	20959818
SET2_YEAST	SET2	genetic	20959818
LGE1_YEAST	LGE1	genetic	20959818
URE2_YEAST	URE2	genetic	20959818
SPT3_YEAST	SPT3	genetic	20959818
UBP6_YEAST	UBP6	genetic	20959818
DOT6_YEAST	DOT6	genetic	20959818
SPT21_YEAST	SPT21	genetic	20959818
GLN3_YEAST	GLN3	genetic	20959818
SEM1_YEAST	SEM1	genetic	20959818
TFB2_YEAST	TFB2	genetic	20959818
GCR2_YEAST	GCR2	genetic	20959818
UBP3_YEAST	UBP3	genetic	20959818
REI1_YEAST	REI1	genetic	21127252
BUB1_YEAST	BUB1	genetic	21127252
BYE1_YEAST	BYE1	genetic	21127252
RTG3_YEAST	RTG3	genetic	21127252
SWF1_YEAST	SWF1	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
YL413_YEAST	INA1	genetic	27708008
SUCA_YEAST	LSC1	genetic	27708008
WDR6_YEAST	RTT10	genetic	27708008
PRS8_HUMAN	PSMC5	physical	27107014
TRI39_HUMAN	TRIM39	physical	27107014
FHL3_HUMAN	FHL3	physical	27107014
GOGA2_HUMAN	GOLGA2	physical	27107014
TEX11_HUMAN	TEX11	physical	27107014

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DAL80_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-111 AND THR-112, ANDMASS SPECTROMETRY.	17563356 [Abstract]