UniProt ID | CWC27_YEAST | |
---|---|---|
UniProt AC | Q02770 | |
Protein Name | Peptidyl-prolyl isomerase CWC27 | |
Gene Name | CWC27 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 301 | |
Subcellular Localization | Cytoplasm . Nucleus . | |
Protein Description | PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing. [PubMed: 11884590] | |
Protein Sequence | MSSNIEPQTTAKCILYTTKGNIAIELWAKECPETCKRFLSMLSDGTFTNGEFKELKPTQWLMFNANSTGEYRTVAEEKNPRIRFNRDGLLGWDRRRNTWFITVLADSKHVLNDCNVFGKIVGKSIYIFREILGGEIEASSRDNDVKRFMYPAVLKDVEITIPFFEDIFGSKRRLEDNEKKEQEPAKKLVKSAKVKMVYEDEQEDDDGDVQKLKPRKRMILPAWIKDDSRSEGIKLDASLDQPQEALIREKTELHDNVDEATTKETESQENIKEEPMDKRERETLAMLSKFQERIKNKNILK | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
211 | Acetylation | DDDGDVQKLKPRKRM CCCCCHHHCCCCCEE | 59.32 | 24489116 | |
251 | Phosphorylation | EALIREKTELHDNVD HHHHHHHHHHCCCCC | 38.74 | 25704821 | |
265 | Phosphorylation | DEATTKETESQENIK CHHHHHHHHHHHCHH | 42.36 | 24961812 | |
267 | Phosphorylation | ATTKETESQENIKEE HHHHHHHHHHCHHCC | 50.65 | 21440633 | |
289 | Acetylation | ETLAMLSKFQERIKN HHHHHHHHHHHHHHC | 47.29 | 24489116 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CWC27_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CWC27_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CWC27_YEAST !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
PML1_YEAST | PML1 | genetic | 19061648 | |
POP8_YEAST | POP8 | genetic | 19061648 | |
CWC26_YEAST | BUD13 | genetic | 19061648 | |
IST3_YEAST | IST3 | genetic | 19061648 | |
NCBP1_YEAST | STO1 | genetic | 19061648 | |
ERF3_YEAST | SUP35 | genetic | 19061648 | |
DOA1_YEAST | DOA1 | genetic | 19061648 | |
PFD2_YEAST | GIM4 | genetic | 19061648 | |
PP12_YEAST | GLC7 | genetic | 19061648 | |
SSB1_YEAST | SSB1 | physical | 19536198 | |
LTE1_YEAST | LTE1 | genetic | 27708008 | |
WHI4_YEAST | WHI4 | genetic | 27708008 | |
CWC26_YEAST | BUD13 | genetic | 27708008 | |
SKN1_YEAST | SKN1 | genetic | 27708008 | |
IST3_YEAST | IST3 | genetic | 27708008 | |
DAL81_YEAST | DAL81 | genetic | 27708008 | |
PHD1_YEAST | PHD1 | genetic | 27708008 | |
PML1_YEAST | PML1 | genetic | 27708008 | |
VAM3_YEAST | VAM3 | genetic | 27708008 | |
SUCA_YEAST | LSC1 | genetic | 27708008 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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