AIM9_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AIM9_YEAST
• UniProt AC: P40053
• Protein Name: Altered inheritance of mitochondria protein 9, mitochondrial
• Gene Name: AIM9
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 627
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MIRYTVAGHSRRCVVGASKRVGAIKCITVAATKRFISNKPNEVFTKLTNDNDPKRDAFFKYTWGSWLKNDKQEKEKRFTKFSIEGLNRILNDIYIQSNEMAKAPDGKILPPVFNKNLTVSLVNNVVPKNIGKINPNEKVQVTTLSSIHEGKHHRIYKVDTNLNKAFILRIPYPLENENTLSYRIRSEVATMDFADLKLGIKVPKIFCYGVNSLNPVRQPFVLQEFIEGELLMKDWDPLIEDGSSNQKKYDNVIKQVSDFQSKLVSLKLNAFGSIYFNNDLKDGNEKEFVKEDIYDGETNPDLQNRWKIGPSVERCLWRHKSHLDFHKQMKPFLGPWPKKSPMDIIKNTGLLEAENAKTRIAMKEAGSSAELMYPRTLKEQITTYENLAKIAPDLFNVKTKAIPNMQELLSPRLFHPDLDPMNIIVNKEAQEAYLLDFEGACTKPFILQNSPQFIAYDGPKIYDLKEDITDFDKLSEAEKVQYQFMYKRTRNQHQWEKKLNDNNPKLITAVAPPVKLLRSPYIAAVERKTEEEYLLIDESLLQLKEVWDIFAQNELVNQKKFPLNYSKEDIERHVEDLQKLHEKLISTPFAATQGWIPQDMFDQLLNSGSIVKQENGDYTVKQPEATK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Acetylation	LTNDNDPKRDAFFKY HCCCCCCCCCHHHHH	66.81	24489116
61	Phosphorylation	KRDAFFKYTWGSWLK CCCHHHHHHHHHHHH	11.54	30377154
68	Acetylation	YTWGSWLKNDKQEKE HHHHHHHHCCHHHHH	57.76	24489116
80	Acetylation	EKEKRFTKFSIEGLN HHHHHHHHHHHHHHH	34.11	24489116
102	Acetylation	IQSNEMAKAPDGKIL HCCCCCCCCCCCCCC	60.17	24489116
115	Acetylation	ILPPVFNKNLTVSLV CCCCCCCCCCEEEEE	41.70	24489116
138	Acetylation	GKINPNEKVQVTTLS CCCCCCCCEEEEECC	44.61	24489116
151	Acetylation	LSSIHEGKHHRIYKV CCCCCCCCCCEEEEE	33.00	22865919
156	Phosphorylation	EGKHHRIYKVDTNLN CCCCCEEEEEECCCC	12.62	19823750
160	Phosphorylation	HRIYKVDTNLNKAFI CEEEEEECCCCEEEE	44.59	19823750
262	Acetylation	QVSDFQSKLVSLKLN HHHHHHHHHHHCCCC	41.97	24489116
273	Phosphorylation	LKLNAFGSIYFNNDL CCCCCCCCEEECCCC	13.99	24909858
281	Acetylation	IYFNNDLKDGNEKEF EEECCCCCCCCCCHH	67.46	22865919
290	Acetylation	GNEKEFVKEDIYDGE CCCCHHEECCCCCCC	55.80	24489116
389	Acetylation	TTYENLAKIAPDLFN HHHHHHHHHCHHHHC	42.43	24489116
398	Acetylation	APDLFNVKTKAIPNM CHHHHCCCCCCCCCH	45.47	24489116
410	Phosphorylation	PNMQELLSPRLFHPD CCHHHHHCCCCCCCC	22.16	28889911
465	Acetylation	GPKIYDLKEDITDFD CCCEECCCCCCCCHH	50.90	24489116
473	Acetylation	EDITDFDKLSEAEKV CCCCCHHHCCHHHHH	54.64	24489116
498	Acetylation	NQHQWEKKLNDNNPK CHHHHHHHHCCCCCC	40.79	24489116
505	Acetylation	KLNDNNPKLITAVAP HHCCCCCCEEEEECC	55.43	24489116
515	Acetylation	TAVAPPVKLLRSPYI EEECCCHHHHCCCCE	47.80	24489116
559	Acetylation	QNELVNQKKFPLNYS HCCHHCCCCCCCCCC	51.70	24489116
567	Acetylation	KFPLNYSKEDIERHV CCCCCCCHHHHHHHH	49.39	24489116
579	Acetylation	RHVEDLQKLHEKLIS HHHHHHHHHHHHHHC	60.14	22865919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AIM9_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AIM9_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AIM9_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RL4A_YEAST	RPL4A	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
ODO2_YEAST	KGD2	genetic	27708008
SDHX_YEAST	YJL045W	genetic	27708008
YJ24_YEAST	KCH1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.