| UniProt ID | ZPR1_YEAST | |
|---|---|---|
| UniProt AC | P53303 | |
| Protein Name | Zinc finger protein ZPR1 | |
| Gene Name | ZPR1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 486 | |
| Subcellular Localization | Cytoplasm. Nucleus. Translocates to the nucleus after nutrient stimulation. | |
| Protein Description | ||
| Protein Sequence | MSEQKEDLFKPVGEAAAEVEDESIAEQNKANDGVKLTGAQDAMGHPVQEIESLCMNCGKNGTTRLLLTSIPYFREIIIMSFDCPHCGFKNCEIQPASQIQEKGSRYVLKVECREDFNRQVIKSETATCKFVELDIEIPAKRGQLTTVEGLLSEMIDDLSQDQEMRKSIDEALYKKIDDFIQKVKSYINCEPNTIPITFILDDPAGNSWIEYKPGEPQHKWSHTQYVRTDEQNVQVGIITRDQLEQRRQEQLKQLANRERNPSESVKVGSANPQFLSDATDIENFNNEVQTFRASCPSCTQECETHMKPVNIPHFKEVIIMSTVCDHCGYKSNEVKTGGAIPDKGRRITLYCDDAADLSRDILKSETCSMVIPELHLDIQEGTLGGRFTTLEGLLRQVYEELESRIFTQTSDSMDEATKARWVEFFAKLKEAIAGKVKFTVIMEDPLAGSYIQNVYAPDPDPNMTIEDYERTKEQNEDLGLSDIKVE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSEQKEDLF ------CCHHHHHHC | 49.05 | 30377154 | |
| 5 | Acetylation | ---MSEQKEDLFKPV ---CCHHHHHHCHHH | 49.50 | 24489116 | |
| 10 | Acetylation | EQKEDLFKPVGEAAA HHHHHHCHHHHHHHH | 46.20 | 24489116 | |
| 23 | Phosphorylation | AAEVEDESIAEQNKA HHHHCCHHHHHHHHC | 39.15 | 22369663 | |
| 89 | Ubiquitination | DCPHCGFKNCEIQPA CCCCCCCCCCEEEEH | 46.07 | 17644757 | |
| 102 | Acetylation | PASQIQEKGSRYVLK EHHHHHHCCCEEEEE | 45.90 | 24489116 | |
| 102 | Ubiquitination | PASQIQEKGSRYVLK EHHHHHHCCCEEEEE | 45.90 | 23749301 | |
| 122 | Ubiquitination | DFNRQVIKSETATCK CHHHHHEECCCCEEE | 43.30 | 23749301 | |
| 140 | Ubiquitination | LDIEIPAKRGQLTTV EEEECCCCCCCCEEH | 52.27 | 24961812 | |
| 167 | Phosphorylation | QDQEMRKSIDEALYK CCHHHHHHHHHHHHH | 25.55 | 28889911 | |
| 182 | Acetylation | KIDDFIQKVKSYINC HHHHHHHHHHHHHCC | 46.98 | 24489116 | |
| 262 | Phosphorylation | ANRERNPSESVKVGS HHCCCCHHHCCCCCC | 46.16 | 20377248 | |
| 264 | Phosphorylation | RERNPSESVKVGSAN CCCCHHHCCCCCCCC | 31.41 | 24961812 | |
| 269 | Phosphorylation | SESVKVGSANPQFLS HHCCCCCCCCHHHCC | 28.06 | 21551504 | |
| 276 | Phosphorylation | SANPQFLSDATDIEN CCCHHHCCCCHHHHH | 26.87 | 30377154 | |
| 343 | Ubiquitination | TGGAIPDKGRRITLY CCCCCCCCCCEEEEE | 49.30 | 23749301 | |
| 407 | Phosphorylation | ELESRIFTQTSDSMD HHHHCHHCCCCCCCC | 28.68 | 25752575 | |
| 412 | Phosphorylation | IFTQTSDSMDEATKA HHCCCCCCCCHHHHH | 28.09 | 30377154 | |
| 418 | Ubiquitination | DSMDEATKARWVEFF CCCCHHHHHHHHHHH | 42.90 | 23749301 | |
| 472 | Ubiquitination | IEDYERTKEQNEDLG HHHHHHHHHHCCCCC | 64.62 | 23749301 | |
| 484 | Ubiquitination | DLGLSDIKVE----- CCCCCCCCCC----- | 45.35 | 23749301 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ZPR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ZPR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ZPR1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-167 AND THR-407, ANDMASS SPECTROMETRY. | |