COPZ_YEAST - dbPTM
COPZ_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COPZ_YEAST
UniProt AC P53600
Protein Name Coatomer subunit zeta
Gene Name RET3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 189
Subcellular Localization Cytoplasm. Golgi apparatus membrane
Peripheral membrane protein
Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane
Peripheral membrane protein
Cytoplasmic side. The coatomer is cytoplasmic or polymerized on the cytoplasmic side o
Protein Description The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex..
Protein Sequence MSSLSLYTVQAVLILDQQGERIYAKYYQPPHRSDEGHQLLFNSVKKQKEFEKQLYRKTHKQDSEILIFEDHLVLYKEYIDITIYLVASLEENEIVLQQGFSAIRGALDLILNSGMDKKNIQENYDMVLLAIDETIDNGVILETDSNTIASRVSKPPTNEPQMALDLDKGFLGAWGFAKSKFQERLQQGL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSSLSLYTV
------CCCCCEEEE		39.7328889911
5Phosphorylation---MSSLSLYTVQAV
---CCCCCEEEEEEE		22.6828889911
8PhosphorylationMSSLSLYTVQAVLIL
CCCCCEEEEEEEEEE		16.0728889911
23PhosphorylationDQQGERIYAKYYQPP
CCCCCEEEEEECCCC		11.8528889911
45AcetylationQLLFNSVKKQKEFEK
HHHHHHHHHHHHHHH		49.6724489116
60UbiquitinationQLYRKTHKQDSEILI
HHHHHHCCCCCEEEE		62.1223749301
63PhosphorylationRKTHKQDSEILIFED
HHHCCCCCEEEEEEC		24.8428889911
75PhosphorylationFEDHLVLYKEYIDIT
EECCEEEEHHHHHEE		8.3628889911
117AcetylationILNSGMDKKNIQENY
HHCCCCCHHHHHHHC		38.5424489116
178AcetylationLGAWGFAKSKFQERL
HHHHHHHHHHHHHHH		52.5024489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COPZ_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COPZ_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COPZ_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
IRE1_YEASTIRE1genetic
12176018
RBD2_YEASTRBD2physical
18467557
COPG_YEASTSEC21physical
22246286
HSP72_YEASTSSA2physical
22940862
SSB1_YEASTSSB1physical
22940862
HSP71_YEASTSSA1physical
22940862
SHG1_YEASTSHG1genetic
27708008
RT103_YEASTRTT103genetic
27708008
BCK1_YEASTBCK1genetic
27708008
GAS1_YEASTGAS1genetic
27708008
TRS20_YEASTTRS20genetic
27708008
USO1_YEASTUSO1genetic
27708008
COPA_YEASTCOP1genetic
27708008
CDC1_YEASTCDC1genetic
27708008
COPB_YEASTSEC26genetic
27708008
TRS23_YEASTTRS23genetic
27708008
COG3_YEASTCOG3genetic
27708008
YPT1_YEASTYPT1genetic
27708008
COPD_YEASTRET2genetic
27708008
HSF_YEASTHSF1genetic
27708008
ARP4_YEASTARP4genetic
27708008
BET3_YEASTBET3genetic
27708008
SEN1_YEASTSEN1genetic
27708008
SEC39_YEASTSEC39genetic
27708008
BET5_YEASTBET5genetic
27708008
VTI1_YEASTVTI1genetic
27708008
VPS8_YEASTVPS8genetic
27708008
SWC5_YEASTSWC5genetic
27708008
CHK1_YEASTCHK1genetic
27708008
STE50_YEASTSTE50genetic
27708008
TGL2_YEASTTGL2genetic
27708008
TRS85_YEASTTRS85genetic
27708008
DHAS_YEASTHOM2genetic
27708008
MNN10_YEASTMNN10genetic
27708008
PHM6_YEASTPHM6genetic
27708008
VPS74_YEASTVPS74genetic
27708008
RLA4_YEASTRPP2Bgenetic
27708008
SHE9_YEASTSHE9genetic
27708008
UBP3_YEASTUBP3genetic
27708008
COG7_YEASTCOG7genetic
27708008
ERV14_YEASTERV14genetic
27708008
PEX14_YEASTPEX14genetic
27708008
RAD54_YEASTRAD54genetic
27708008
ATC1_YEASTPMR1genetic
27708008
HUR1_YEASTHUR1genetic
27708008
ACOX_YEASTPOX1genetic
27708008
PSA3_YEASTPRE9genetic
27708008
SNF6_YEASTSNF6genetic
27708008
GOSR1_YEASTGOS1genetic
27708008
SDS3_YEASTSDS3genetic
27708008
VPS53_YEASTVPS53genetic
27708008
PHO86_YEASTPHO86genetic
27708008
RAV1_YEASTRAV1genetic
27708008
HOC1_YEASTHOC1genetic
27708008
NNK1_YEASTNNK1genetic
27708008
SAC1_YEASTSAC1genetic
27708008
MEH1_YEASTMEH1genetic
27708008
IRS4_YEASTIRS4genetic
27708008
VPS51_YEASTVPS51genetic
27708008
RT109_YEASTRTT109genetic
27708008
RIC1_YEASTRIC1genetic
27708008
RSSA2_YEASTRPS0Bgenetic
27708008
ENV10_YEASTENV10genetic
27708008
UPS1_YEASTUPS1genetic
27708008
YPT6_YEASTYPT6genetic
27708008
SEC22_YEASTSEC22genetic
27708008
TMA10_YEASTTMA10genetic
27708008
VPS38_YEASTVPS38genetic
27708008
ELO3_YEASTELO3genetic
27708008
COG8_YEASTCOG8genetic
27708008
IMP2_YEASTIMP2genetic
27708008
GBLP_YEASTASC1genetic
27708008
SKY1_YEASTSKY1genetic
27708008
SCS7_YEASTSCS7genetic
27708008
COG6_YEASTCOG6genetic
27708008
COG5_YEASTCOG5genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
BRE5_YEASTBRE5genetic
27708008
SIN3_YEASTSIN3genetic
27708008
TLG2_YEASTTLG2genetic
27708008
YO087_YEASTDUF1genetic
27708008
GYP1_YEASTGYP1genetic
27708008
VPS21_YEASTVPS21genetic
27708008
CEX1_YEASTCEX1genetic
27708008
LEO1_YEASTLEO1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COPZ_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory