| UniProt ID | COG7_YEAST | |
|---|---|---|
| UniProt AC | P53195 | |
| Protein Name | Conserved oligomeric Golgi complex subunit 7 | |
| Gene Name | COG7 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 279 | |
| Subcellular Localization |
Golgi apparatus membrane Peripheral membrane protein. |
|
| Protein Description | Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.. | |
| Protein Sequence | MVELTITGDDDDILSMFFDEEFVPHAFVDILLSNALNEDQIQTQSVSSLLLTRLDFYTKNLTKELESTIWNLDKLSQTLPRTWASSRYHKEAEQNDSSLYSTESLKSSKLEYYLDTLASAVRALETGMHNVTEKLSDLDNENNRNTNVRQQLQSLMLIKERIEKVVYYLEQVRTVTNISTVRENNTTSTGTDLSITDFRTSLKALEDTIDESLSSAIDNEAKDETNKDLIGRIDSLSELKCLFKGLDKFFAEYSNFSESIKSKAQSYLSTKNIDDGMIS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 215 | Phosphorylation | TIDESLSSAIDNEAK HHCHHHHHHHCHHHC | 34.24 | 28889911 | |
| 235 | Phosphorylation | DLIGRIDSLSELKCL HHHHHHHHHHHHHHH | 31.27 | 22369663 | |
| 237 | Phosphorylation | IGRIDSLSELKCLFK HHHHHHHHHHHHHHH | 44.85 | 22369663 | |
| 253 | Phosphorylation | LDKFFAEYSNFSESI HHHHHHHHCCCCHHH | 12.89 | 28889911 | |
| 254 | Phosphorylation | DKFFAEYSNFSESIK HHHHHHHCCCCHHHH | 23.93 | 28889911 | |
| 262 | Phosphorylation | NFSESIKSKAQSYLS CCCHHHHHHHHHHHC | 31.39 | 28889911 | |
| 269 | Phosphorylation | SKAQSYLSTKNIDDG HHHHHHHCCCCCCCC | 29.15 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of COG7_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of COG7_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of COG7_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-235, AND MASSSPECTROMETRY. | |
