| UniProt ID | MNN2_YEAST | |
|---|---|---|
| UniProt AC | P38069 | |
| Protein Name | Alpha-1,2-mannosyltransferase MNN2 | |
| Gene Name | MNN2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 597 | |
| Subcellular Localization |
Golgi apparatus membrane Single-pass type II membrane protein . Golgi localization depends on SVP26. |
|
| Protein Description | Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides.. | |
| Protein Sequence | MLLTKRFSKLFKLTFIVLILCGLFVITNKYMDENTSVKEYKEYLDRYVQSYSNKYSSSSDAASADDSTPLRDNDEAGNEKLKSFYNNVFNFLMVDSPKGSTAKQYNEACLLKGDIGDRPDHYKDLYKLSAKELSKCLELSPDEVASLTKSHKDYVEHIATLVSPKGTYKGSGIATVGGGKFSLMAFLIIKTLRNMGTTLPVEVLIPPGDEGETEFCNKILPKYNSKCIYVSDILPRETIEKFVFKGYQFKSLALIASSFENLLLLDADNFPIKPLDNIFNEEPYVSTGLVMWPDFWRRTTHPLYYDIAGIAVDKKKRVRNSRDDITPPAVYTKDLKDLSDVPLSDLDGTIPDVSTESGQLMINKTKHLATALLSLFYNVNGPTWYYPIFSQKAAGEGDKETFIAAANFYGLSFYQVRTRTGVEGYHDEDGFHGVAMLQHDFVQDYGRYLNAMESIGNKYGGTKSADAIKFDKNYSLEKYTEEFFDNEDLNAKNHVDVMFIHSNFPKFDPYDLSKSNFLTTNGKPARSYTALKKVKNYDIELENFKVLNEYVCVNKNPFKYLDDLLGQDKTEWKRVCGYITDRLAFLESTHDKAIAGK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 34 | N-linked_Glycosylation | TNKYMDENTSVKEYK HHHHCCCCCCHHHHH | 33.13 | - | |
| 54 | Acetylation | YVQSYSNKYSSSSDA HHHHHCCCCCCCCCC | 40.34 | 24489116 | |
| 80 | Acetylation | NDEAGNEKLKSFYNN CCHHHHHHHHHHHHH | 66.28 | 24489116 | |
| 123 | Acetylation | GDRPDHYKDLYKLSA CCCCCHHHHHHHCCH | 37.53 | 24489116 | |
| 149 | Ubiquitination | DEVASLTKSHKDYVE HHHHHHCHHCHHHHH | 56.72 | 17644757 | |
| 152 | Ubiquitination | ASLTKSHKDYVEHIA HHHCHHCHHHHHHHH | 58.82 | 17644757 | |
| 165 | Ubiquitination | IATLVSPKGTYKGSG HHHHCCCCCCCCCCC | 57.27 | 17644757 | |
| 245 | Acetylation | TIEKFVFKGYQFKSL HHHHHHHCCCCHHHH | 51.94 | 24489116 | |
| 363 | N-linked_Glycosylation | ESGQLMINKTKHLAT CCCCEEEHHHHHHHH | 31.79 | - | |
| 469 | Acetylation | TKSADAIKFDKNYSL CCCCHHEECCCCCCH | 49.59 | 24489116 | |
| 472 | Ubiquitination | ADAIKFDKNYSLEKY CHHEECCCCCCHHHH | 62.00 | 17644757 | |
| 472 | Acetylation | ADAIKFDKNYSLEKY CHHEECCCCCCHHHH | 62.00 | 24489116 | |
| 473 | N-linked_Glycosylation | DAIKFDKNYSLEKYT HHEECCCCCCHHHHH | 33.21 | - | |
| 478 | Ubiquitination | DKNYSLEKYTEEFFD CCCCCHHHHHHHHCC | 63.87 | 17644757 | |
| 492 | Ubiquitination | DNEDLNAKNHVDVMF CCCCCCCCCCEEEEE | 46.65 | 17644757 | |
| 514 | Acetylation | FDPYDLSKSNFLTTN CCHHCCCCCCCCCCC | 57.63 | 24489116 | |
| 559 | Ubiquitination | CVNKNPFKYLDDLLG EECCCHHHCHHHHCC | 46.27 | 17644757 | |
| 569 | Ubiquitination | DDLLGQDKTEWKRVC HHHCCCCHHHHHHHH | 40.22 | 17644757 | |
| 569 | Acetylation | DDLLGQDKTEWKRVC HHHCCCCHHHHHHHH | 40.22 | 24489116 | |
| 573 | Ubiquitination | GQDKTEWKRVCGYIT CCCHHHHHHHHHHHH | 28.81 | 17644757 | |
| 573 | Acetylation | GQDKTEWKRVCGYIT CCCHHHHHHHHHHHH | 28.81 | 24489116 | |
| 592 | Acetylation | FLESTHDKAIAGK-- HHHHHHCHHHCCC-- | 33.80 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MNN2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MNN2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MNN2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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