| UniProt ID | SLY1_YEAST | |
|---|---|---|
| UniProt AC | P22213 | |
| Protein Name | Protein SLY1 | |
| Gene Name | SLY1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 666 | |
| Subcellular Localization |
Cytoplasm. Membrane Peripheral membrane protein. |
|
| Protein Description | Able to suppress the functional loss of YPT1. SLY1 is essential for cell viability. May interact indirectly, or directly with YPT1.. | |
| Protein Sequence | MAVEEIASRKDISLRDMQISAILKMLFLNKDLNNNDNITTITDDIFNQQEIIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQYLDFIVTEPELFSLEISNAYLTLNDPKTTEEEITGLCANIADGLFNTVLTINSIPIIRAAKGGPAEIIAEKLGTKLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFASMFSHSWIYQCMVFDIFKLSRNTVTIPLESKENGTDNTTAKPLATKKYDIEPNDFFWMENSHLPFPEAAENVEAALNTYKEEAAEITRKTGVTNISDLDPNSNNDTVQIQEVVKKLPELTAKKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGSTKTRSRFLDILKDGKTNNLEDKLRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQNKSLEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIMDPLNSSQKNLETTDSYLYIDPKITRGSHTRKPKRQSYNKSLVFVVGGGNYLEYQNLQEWAHSQLHNPKKVMYGSTAITTPAEFLNEISRLGASNSSNNDA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 8 | Phosphorylation | MAVEEIASRKDISLR CCHHHHHHCCCCCHH | 45.59 | 30377154 | |
| 81 | Phosphorylation | DLLKAGITVHSLIKQ HHHHCCCCHHHHHHC | 15.96 | 28889911 | |
| 84 | Phosphorylation | KAGITVHSLIKQDRS HCCCCHHHHHHCCCC | 27.70 | 28889911 | |
| 125 | Phosphorylation | SDKYSEFYINFTSSL CCCCCEEEEECCCCC | 7.30 | 19779198 | |
| 131 | Phosphorylation | FYINFTSSLPRNLLE EEEECCCCCCHHHHH | 39.06 | 19779198 | |
| 230 | Acetylation | PAEIIAEKLGTKLRD CHHHHHHHHCCCHHH | 43.10 | 24489116 | |
| 296 | Phosphorylation | KLSRNTVTIPLESKE CCCCCEEEEECCCCC | 18.16 | 27017623 | |
| 312 | Ubiquitination | GTDNTTAKPLATKKY CCCCCCCCCCCCCCC | 38.17 | 23749301 | |
| 391 | Phosphorylation | VKKLPELTAKKNTID HHHCHHHHCCCCCHH | 34.47 | 28889911 | |
| 440 | Acetylation | SRFLDILKDGKTNNL HHHHHHHHHCCCCCH | 65.84 | 24489116 | |
| 453 | Phosphorylation | NLEDKLRSFIVLYLT CHHHHHHHHHHHHHH | 29.75 | 19779198 | |
| 463 | Phosphorylation | VLYLTSTTGLPKDFV HHHHHCCCCCCHHHH | 36.17 | 19779198 | |
| 508 | Phosphorylation | NMSLQNKSLEDGSDS CCCCCCCCCCCCCCC | 44.53 | 21440633 | |
| 523 | Phosphorylation | AFKPSNLTLSGIYGL CCCCCCEEEEEEEEC | 24.11 | 24961812 | |
| 525 | Phosphorylation | KPSNLTLSGIYGLTE CCCCEEEEEEEECCC | 20.22 | 24961812 | |
| 531 | Phosphorylation | LSGIYGLTEGKLQGG EEEEEECCCCCCCCC | 38.03 | 24961812 | |
| 541 | Phosphorylation | KLQGGVGSLISGIKK CCCCCHHHHHHHHHH | 21.81 | 22369663 | |
| 544 | Phosphorylation | GGVGSLISGIKKLLP CCHHHHHHHHHHHCC | 39.50 | 22369663 | |
| 588 | Acetylation | SYLYIDPKITRGSHT EEEEECCCCCCCCCC | 53.62 | 24489116 | |
| 603 | Phosphorylation | RKPKRQSYNKSLVFV CCCCCCCCCCEEEEE | 20.47 | 27017623 | |
| 606 | Phosphorylation | KRQSYNKSLVFVVGG CCCCCCCEEEEEECC | 26.57 | 27017623 | |
| 616 | Phosphorylation | FVVGGGNYLEYQNLQ EEECCCCCEEECCHH | 12.27 | 27017623 | |
| 641 | Phosphorylation | KKVMYGSTAITTPAE CCEECCCCCCCCHHH | 20.09 | 19779198 | |
| 659 | Phosphorylation | EISRLGASNSSNNDA HHHHHCCCCCCCCCC | 35.13 | 19779198 | |
| 661 | Phosphorylation | SRLGASNSSNNDA-- HHHCCCCCCCCCC-- | 31.76 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SLY1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SLY1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SLY1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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