GYP8_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GYP8_YEAST
• UniProt AC: P43570
• Protein Name: GTPase-activating protein GYP8
• Gene Name: GYP8
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 497
• Protein Sequence: MPLRSLFHTNQSSHDKDALTRGGYNAYLESLSRCDSGKAEEQKGKVISKLLEKKDVRALRYIGLGPLGFVNNSLRKDCWYELLASQLLIDDATEYITPVEKHKDEGQVILDAERSFGGIVDKNLKLQLRKLLVELITRVLRKYPTLNYYQGYHDIVSVFIMCFSWNVTKENGLELENLSLQEEIDMERLFYCIEAFTLLYLRDFMMNSLDFSFEQLRVISSLIKESNMKFYNLFKFDENEPLFAIGSILTIFAHNLKPIDSGDNNLHKILFQIFDMTISMQSMRLPLIIYKNLLLQNASEISKQIEANSDFFENDFDLRHGAIQTVLQKKLYDEALWEEVLQITRKDATTASKKALKRVSLNKYSALLNTACGKPGCFDMSTIIFYLSEQTKMNEHYKEEKYHGVAARSKTRALVQRLGHFLPSKYNRWSKISLLIGIVAILYQLRTTRSLSLVLNLRYMISTKLKDLSHININLHHVSHIWVDPIRDILKLGHPTR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Acetylation	TNQSSHDKDALTRGG CCCCCCCHHHHHHCC	39.20	24489116
179	Phosphorylation	GLELENLSLQEEIDM CEEEECCCHHHHCCH	39.32	28889911
352	Phosphorylation	RKDATTASKKALKRV HHCCCHHCHHHHHHH	32.37	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GYP8_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GYP8_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GYP8_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
STX8_YEAST	SYN8	genetic	20093466
MDM10_YEAST	MDM10	genetic	20093466
OSH1_YEAST	SWH1	genetic	20093466
SAS3_YEAST	SAS3	genetic	20093466
C1TM_YEAST	MIS1	genetic	20093466
SIF2_YEAST	SIF2	genetic	20093466
TPS1_YEAST	TPS1	genetic	20093466
BMT2_YEAST	BMT2	genetic	20093466
SWD3_YEAST	SWD3	genetic	20093466
AIM4_YEAST	AIM4	genetic	20093466
SWC5_YEAST	SWC5	genetic	20093466
RMD9L_YEAST	YBR238C	genetic	20093466
MIC12_YEAST	MIC12	genetic	20093466
SSH1_YEAST	SSH1	genetic	20093466
STE50_YEAST	STE50	genetic	20093466
NAA38_YEAST	MAK31	genetic	20093466
SYP1_YEAST	SYP1	genetic	20093466
SNT1_YEAST	SNT1	genetic	20093466
PER1_YEAST	PER1	genetic	20093466
BUD31_YEAST	BUD31	genetic	20093466
YCY0_YEAST	YCR090C	genetic	20093466
AIR2_YEAST	AIR2	genetic	20093466
YD157_YEAST	YDL157C	genetic	20093466
MDHP_YEAST	MDH3	genetic	20093466
BDF2_YEAST	BDF2	genetic	20093466
PEX19_YEAST	PEX19	genetic	20093466
PRM7_YEAST	PRM7	genetic	20093466
RPN4_YEAST	RPN4	genetic	20093466
TGL2_YEAST	TGL2	genetic	20093466
TPS2_YEAST	TPS2	genetic	20093466
YD090_YEAST	YDR090C	genetic	20093466
PEX7_YEAST	PEX7	genetic	20093466
MKC7_YEAST	MKC7	genetic	20093466
HMO1_YEAST	HMO1	genetic	20093466
CSN9_YEAST	CSN9	genetic	20093466
GNTK_YEAST	YDR248C	genetic	20093466
PEX10_YEAST	PEX10	genetic	20093466
DPP1_YEAST	DPP1	genetic	20093466
MRB1_YEAST	PHO92	genetic	20093466
BCS1_YEAST	BCS1	genetic	20093466
LSM6_YEAST	LSM6	genetic	20093466
RLA4_YEAST	RPP2B	genetic	20093466
CP56_YEAST	DIT2	genetic	20093466
DIT1_YEAST	DIT1	genetic	20093466
PDR15_YEAST	PDR15	genetic	20093466
ARO80_YEAST	ARO80	genetic	20093466
HXT8_YEAST	HXT8	genetic	20093466
RPE_YEAST	RPE1	genetic	20093466
MOG1_YEAST	MOG1	genetic	20093466
SWI6_YEAST	SWI6	genetic	20093466
GGPPS_YEAST	BTS1	genetic	20093466
COG5_YEAST	COG5	genetic	19325107
UBX2_YEAST	UBX2	genetic	19325107
SWI6_YEAST	SWI6	genetic	27708008
ATG1_YEAST	ATG1	genetic	27708008
GIC1_YEAST	GIC1	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.