| UniProt ID | MDHP_YEAST | |
|---|---|---|
| UniProt AC | P32419 | |
| Protein Name | Malate dehydrogenase, peroxisomal | |
| Gene Name | MDH3 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 343 | |
| Subcellular Localization | Peroxisome. | |
| Protein Description | ||
| Protein Sequence | MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Phosphorylation | KVAILGASGGVGQPL EEEEECCCCCCCCCH | 33.99 | 19684113 | |
| 28 | Phosphorylation | LKLSPYVSELALYDI HHHCCCCHHHHHHHH | 22.50 | 27214570 | |
| 46 | Phosphorylation | EGIGKDLSHINTNSS CCCCCCCCCCCCCCC | 32.24 | 28889911 | |
| 91 | Acetylation | LTRDDLFKMNAGIVK CCHHHHHHCCHHHHH | 38.24 | 24489116 | |
| 106 | Ubiquitination | SLVTAVGKFAPNARI HHHHHHHHCCCCCEE | 31.58 | 23749301 | |
| 106 | Acetylation | SLVTAVGKFAPNARI HHHHHHHHCCCCCEE | 31.58 | 24489116 | |
| 117 | Phosphorylation | NARILVISNPVNSLV CCEEEEEECCCHHHH | 27.83 | 22369663 | |
| 122 | Phosphorylation | VISNPVNSLVPIAVE EEECCCHHHHHHHHH | 30.86 | 22369663 | |
| 130 | Phosphorylation | LVPIAVETLKKMGKF HHHHHHHHHHHCCCC | 36.96 | 22369663 | |
| 133 | Ubiquitination | IAVETLKKMGKFKPG HHHHHHHHCCCCCCC | 56.87 | 22817900 | |
| 136 | Acetylation | ETLKKMGKFKPGNVM HHHHHCCCCCCCCCC | 46.87 | 24489116 | |
| 136 | Ubiquitination | ETLKKMGKFKPGNVM HHHHHCCCCCCCCCC | 46.87 | 22817900 | |
| 138 | Ubiquitination | LKKMGKFKPGNVMGV HHHCCCCCCCCCCCC | 56.34 | 23749301 | |
| 164 | Ubiquitination | LVDYLMLKNPKIGQE HHHHHHHHCCCCCCC | 58.18 | 22817900 | |
| 164 | Acetylation | LVDYLMLKNPKIGQE HHHHHHHHCCCCCCC | 58.18 | 24489116 | |
| 167 | Ubiquitination | YLMLKNPKIGQEQDK HHHHHCCCCCCCCCC | 69.71 | 23749301 | |
| 174 | Ubiquitination | KIGQEQDKTTMHRKV CCCCCCCCCCCEEEE | 45.66 | 23749301 | |
| 207 | Acetylation | SLVFQLDKQYEHFIH HHEEEHHHHHHHHHH | 64.47 | 24489116 | |
| 225 | Ubiquitination | FGGDEIVKAKQGAGS ECCHHHEECCCCCCC | 56.37 | 23749301 | |
| 227 | Ubiquitination | GDEIVKAKQGAGSAT CHHHEECCCCCCCHH | 43.47 | 22817900 | |
| 256 | Ubiquitination | LRSFHNEKPETESLS HHHHCCCCCCCCCEE | 54.17 | 23749301 | |
| 324 | Acetylation | QLVNTAVKELRKNIE HHHHHHHHHHHHHHH | 48.87 | 24489116 | |
| 324 | Ubiquitination | QLVNTAVKELRKNIE HHHHHHHHHHHHHHH | 48.87 | 23749301 | |
| 335 | Phosphorylation | KNIEKGKSFILDSSK HHHHHCCCEEECCCC | 26.62 | 27214570 | |
| 341 | Phosphorylation | KSFILDSSKL----- CCEEECCCCC----- | 37.33 | 21440633 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MDHP_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MDHP_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MDHP_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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