TIR4_YEAST - dbPTM
TIR4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TIR4_YEAST
UniProt AC Q12218
Protein Name Cell wall protein TIR4
Gene Name TIR4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 487
Subcellular Localization Secreted, cell wall . Membrane
Lipid-anchor, GPI-anchor .
Protein Description Component of the cell wall. Required for anaerobic growth..
Protein Sequence MAYSKITLLAALAAIAYAQTQAQINELNVVLDDVKTNIADYITLSYTPNSGFSLDQMPAGIMDIAAQLVANPSDDSYTTLYSEVDFSAVEHMLTMVPWYSSRLLPELEAMDASLTTSSSAATSSSEVASSSIASSTSSSVAPSSSEVVSSSVAPSSSEVVSSSVAPSSSEVVSSSVASSSSEVASSSVAPSSSEVVSSSVASSSSEVASSSVAPSSSEVVSSSVAPSSSEVVSSSVASSSSEVASSSVAPSSSEVVSSSVASSTSEATSSSAVTSSSAVSSSTESVSSSSVSSSSAVSSSEAVSSSPVSSVVSSSAGPASSSVAPYNSTIASSSSTAQTSISTIAPYNSTTTTTPASSASSVIISTRNGTTVTETDNTLVTKETTVCDYSSTSAVPASTTGYNNSTKVSTATICSTCKEGTSTATDFSTLKTTVTVCDSACQAKKSATVVSVQSKTTGIVEQTENGAAKAVIGMGAGALAAVAAMLL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
327N-linked_GlycosylationSSSVAPYNSTIASSS
CCCCCCCCCCCCCCC
31.45-
348N-linked_GlycosylationISTIAPYNSTTTTTP
ECCCCCCCCCCCCCC
31.64-
368N-linked_GlycosylationSVIISTRNGTTVTET
EEEEECCCCCEEEEC
52.86-
403N-linked_GlycosylationPASTTGYNNSTKVST
CCCCCCCCCCCCEEE
37.00-
404N-linked_GlycosylationASTTGYNNSTKVSTA
CCCCCCCCCCCEEEE
42.44-
465GPI-anchorGIVEQTENGAAKAVI
CCEEECCCCHHHHHH
49.11-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TIR4_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TIR4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TIR4_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZPR1_YEASTZPR1physical
16554755
TOP1_YEASTTOP1physical
16554755
RV161_YEASTRVS161genetic
20093466
RV167_YEASTRVS167genetic
20093466
FAR7_YEASTFAR7genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
AAKG_YEASTSNF4genetic
20093466
PIB2_YEASTPIB2genetic
20093466
QCR9_YEASTQCR9genetic
20093466
PACC_YEASTRIM101genetic
20093466
COPE_YEASTSEC28genetic
20093466
YJ90_YEASTYJR120Wgenetic
20093466
PEX1_YEASTPEX1genetic
20093466
MEH1_YEASTMEH1genetic
20093466
PSR1_YEASTPSR1genetic
20093466
DNM1_YEASTDNM1genetic
20093466
PFKA2_YEASTPFK2genetic
20093466
SWS2_YEASTSWS2genetic
20093466
BRE5_YEASTBRE5genetic
20093466
LGE1_YEASTLGE1genetic
20093466
AXL1_YEASTAXL1genetic
20093466
CSG2_YEASTCSG2genetic
27708008
FAT1_YEASTFAT1genetic
27708008
ECM8_YEASTECM8genetic
27708008
RV161_YEASTRVS161genetic
27708008
RIM1_YEASTRIM1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
TPS2_YEASTTPS2genetic
27708008
RPA14_YEASTRPA14genetic
27708008
RV167_YEASTRVS167genetic
27708008
AAKG_YEASTSNF4genetic
27708008
FIS1_YEASTFIS1genetic
27708008
FKH1_YEASTFKH1genetic
27708008
DPOD3_YEASTPOL32genetic
27708008
VPS24_YEASTVPS24genetic
27708008
NNK1_YEASTNNK1genetic
27708008
LST4_YEASTLST4genetic
27708008
PEX1_YEASTPEX1genetic
27708008
MEH1_YEASTMEH1genetic
27708008
DNM1_YEASTDNM1genetic
27708008
PSR1_YEASTPSR1genetic
27708008
SIC1_YEASTSIC1genetic
27708008
SSO2_YEASTSSO2genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
SWS2_YEASTSWS2genetic
27708008
FAR11_YEASTFAR11genetic
27708008
VPS27_YEASTVPS27genetic
27708008
BRE5_YEASTBRE5genetic
27708008
LGE1_YEASTLGE1genetic
27708008
VPS4_YEASTVPS4genetic
27708008
QCR2_YEASTQCR2genetic
27708008
CDC1_YEASTCDC1genetic
29674565
SAC7_YEASTSAC7genetic
29674565
DCC1_YEASTDCC1genetic
29674565
SLX5_YEASTSLX5genetic
29674565
HOS2_YEASTHOS2genetic
29674565
LIPA_YEASTLIP5genetic
29674565
DPOD_YEASTPOL3genetic
29674565
PDC2_YEASTPDC2genetic
29674565
RIC1_YEASTRIC1genetic
29674565
YPT6_YEASTYPT6genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TIR4_YEAST

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Related Literatures of Post-Translational Modification

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