| UniProt ID | FAT1_YEAST | |
|---|---|---|
| UniProt AC | P38225 | |
| Protein Name | Very long-chain fatty acid transport protein | |
| Gene Name | FAT1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 669 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | May be involved in long-chain fatty acids uptake, and thus may play a pivotal role in regulating their accessibility prior to metabolic utilization. May play an important role in uptake of these hydrophobic compounds under conditions where fatty acid synthesis is compromised.. | |
| Protein Sequence | MSPIQVVVFALSRIFLLLFRLIKLIITPIQKSLGYLFGNYFDELDRKYRYKEDWYIIPYFLKSVFCYIIDVRRHRFQNWYLFIKQVQQNGDHLAISYTRPMAEKGEFQLETFTYIETYNIVLRLSHILHFDYNVQAGDYVAIDCTNKPLFVFLWLSLWNIGAIPAFLNYNTKGTPLVHSLKISNITQVFIDPDASNPIRESEEEIKNALPDVKLNYLEEQDLMHELLNSQSPEFLQQDNVRTPLGLTDFKPSMLIYTSGTTGLPKSAIMSWRKSSVGCQVFGHVLHMTNESTVFTAMPLFHSTAALLGACAILSHGGCLALSHKFSASTFWKQVYLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKVAYGNGLRPDIWQDFRKRFNIEVIGEFYAATEAPFATTTFQKGDFGIGACRNYGTIIQWFLSFQQTLVRMDPNDDSVIYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFRRGDAWYRCGDLLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVPKYEGRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILKKVYREQKLPKGLDGNDTIFWLKNYKRYEVLTAADWEAIDAQTIKL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 32 | Phosphorylation | IITPIQKSLGYLFGN HHHHHHHHHHHHHCC | 15.62 | 29734811 | |
| 35 | Phosphorylation | PIQKSLGYLFGNYFD HHHHHHHHHHCCCHH | 12.26 | 29734811 | |
| 40 | Phosphorylation | LGYLFGNYFDELDRK HHHHHCCCHHHHHHH | 16.88 | 29734811 | |
| 359 | Acetylation | LLHTPISKYEKMHKV HHCCCHHHHHHHHCC | 59.14 | 24489116 | |
| 472 | Acetylation | LMRIFFPKKPETSFQ EEEHHCCCCCCCCCC | 75.66 | 24489116 | |
| 621 | Acetylation | IKMTDNHKILKKVYR CCCCCCHHHHHHHHH | 56.86 | 25381059 | |
| 624 | Acetylation | TDNHKILKKVYREQK CCCHHHHHHHHHHCC | 43.60 | 25381059 | |
| 646 | Acetylation | NDTIFWLKNYKRYEV CCEEEEECCCCEEEE | 49.15 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FAT1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FAT1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FAT1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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