PEX27_YEAST - dbPTM
PEX27_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PEX27_YEAST
UniProt AC Q08580
Protein Name Peroxisomal membrane protein PEX27
Gene Name PEX27
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 376
Subcellular Localization Peroxisome membrane
Peripheral membrane protein .
Protein Description Required for regulation of peroxisome size and number. Also promotes peroxisome division and biogenesis..
Protein Sequence MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPIVLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAKVTSANEHTSAV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationDPVNTNISSPTLTDR
CCCCCCCCCCCCCCC		32.1324961812
12PhosphorylationPVNTNISSPTLTDRN
CCCCCCCCCCCCCCC		20.3627214570
14PhosphorylationNTNISSPTLTDRNAD
CCCCCCCCCCCCCHH		44.2124961812
16PhosphorylationNISSPTLTDRNADES
CCCCCCCCCCCHHHH		35.0827214570
68PhosphorylationVLQDNDDSDFTQNQG
EECCCCCCCCCCCCC		37.1722369663
71PhosphorylationDNDDSDFTQNQGKVA
CCCCCCCCCCCCCEE		31.4422369663
83PhosphorylationKVATATSTTSDRSFK
CEEEEECCCCCHHHH		26.4321440633
85PhosphorylationATATSTTSDRSFKRT
EEEECCCCCHHHHHH		30.9920377248
88PhosphorylationTSTTSDRSFKRTLGS
ECCCCCHHHHHHHCC		39.8620377248
228PhosphorylationILFHKLQSMFGKKNT
HHHHHHHHHHCCCCC		26.9021551504
240PhosphorylationKNTSHANTNRLMTFV
CCCCCCCHHHHHHHH		23.6221551504
345PhosphorylationKYNSELAYEIISVGS
CCCCHHHHHHHHHCC		21.9319684113
349PhosphorylationELAYEIISVGSGVTE
HHHHHHHHHCCHHHH		26.5328889911
352PhosphorylationYEIISVGSGVTELLK
HHHHHHCCHHHHHHH		28.1219684113
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PEX27_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PEX27_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PEX27_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PEX27_YEASTPEX27physical
14517321
PEX11_YEASTPEX11genetic
14517338
BLM10_YEASTBLM10genetic
27708008
HAP3_YEASTHAP3genetic
27708008
NU170_YEASTNUP170genetic
27708008
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
RIM1_YEASTRIM1genetic
27708008
BUD31_YEASTBUD31genetic
27708008
DBP3_YEASTDBP3genetic
27708008
PFD3_YEASTPAC10genetic
27708008
VMA21_YEASTVMA21genetic
27708008
STB5_YEASTSTB5genetic
27708008
IMPX_YEASTIMP2genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
LPLA_YEASTAIM22genetic
27708008
ASF1_YEASTASF1genetic
27708008
YJQ3_YEASTYJL163Cgenetic
27708008
ILM1_YEASTILM1genetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
SWS2_YEASTSWS2genetic
27708008
MET22_YEASTMET22genetic
27708008
RMI1_YEASTRMI1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
YP260_YEASTYPL260Wgenetic
27708008
QCR2_YEASTQCR2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PEX27_YEAST

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Related Literatures of Post-Translational Modification

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