PLSC_YEAST - dbPTM
PLSC_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PLSC_YEAST
UniProt AC P33333
Protein Name Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
Gene Name SLC1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 303
Subcellular Localization Membrane
Single-pass membrane protein .
Protein Description May be an acyltransferase with an altered substrate specificity that enables it to use a C-26-CoA in place of the C-16 or C-18-CoAs used by the wild-type protein..
Protein Sequence MSVIGRFLYYLRSVLVVLALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAKKPYIMIANHQSTLDIFMLGRIFPPGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVNTHNEGSSVKKMH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
136PhosphorylationKRQEAIDTLNKGLEN
HHHHHHHHHHHHHHH		26.5619795423
182UbiquitinationFHLAQQGKIPIVPVV
HHHHHCCCCCEEEEE		40.7617644757
200UbiquitinationTSTLVSPKYGVFNRG
CCCCCCCCCCCCCCC		47.3217644757
200AcetylationTSTLVSPKYGVFNRG
CCCCCCCCCCCCCCC		47.3224489116
215AcetylationCMIVRILKPISTENL
EEEEEECCCCCCCCC		37.6224489116
218PhosphorylationVRILKPISTENLTKD
EEECCCCCCCCCCHH		37.8927214570
219PhosphorylationRILKPISTENLTKDK
EECCCCCCCCCCHHH		29.6127214570
224AcetylationISTENLTKDKIGEFA
CCCCCCCHHHHHHHH		61.2624489116
270AcetylationYAALQHDKKVNKKIK
HHHHHCCHHHCHHCC		57.4024489116
274UbiquitinationQHDKKVNKKIKNEPV
HCCHHHCHHCCCCCC		59.8817644757
275UbiquitinationHDKKVNKKIKNEPVP
CCHHHCHHCCCCCCC		54.4217644757
277UbiquitinationKKVNKKIKNEPVPSV
HHHCHHCCCCCCCCE		65.2317644757
292PhosphorylationSISNDVNTHNEGSSV
EEECCCCCCCCCCCC		26.4027717283
297PhosphorylationVNTHNEGSSVKKMH-
CCCCCCCCCCCCCC-		26.2721440633
298PhosphorylationNTHNEGSSVKKMH--
CCCCCCCCCCCCC--		49.1420377248
300UbiquitinationHNEGSSVKKMH----
CCCCCCCCCCC----		46.4517644757
301UbiquitinationNEGSSVKKMH-----
CCCCCCCCCC-----		39.8017644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PLSC_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PLSC_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PLSC_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TCPD_YEASTCCT4physical
11805826
ECM29_YEASTECM29physical
11805826
GCN1_YEASTGCN1physical
11805826
GCN20_YEASTGCN20physical
11805826
IMB4_YEASTKAP123physical
11805826
MED14_YEASTRGR1physical
11805826
SEC7_YEASTSEC7physical
11805826
CAP_YEASTSRV2physical
11805826
ALE1_YEASTALE1genetic
16269340
GET2_YEASTGET2genetic
16269340
PMT1_YEASTPMT1genetic
16269340
RGP1_YEASTRGP1genetic
16269340
PMT5_YEASTPMT5genetic
16269340
RIC1_YEASTRIC1genetic
16269340
OSH2_YEASTOSH2genetic
16269340
ERP3_YEASTERP3genetic
16269340
OST6_YEASTOST6genetic
16269340
ORM2_YEASTORM2genetic
16269340
ICE2_YEASTICE2genetic
16269340
CHO2_YEASTCHO2genetic
16269340
ALE1_YEASTALE1genetic
17675291
ELO2_YEASTELO2genetic
17726007
PMT5_YEASTPMT5genetic
17726007
ALE1_YEASTALE1genetic
17726007
AYR1_YEASTAYR1physical
18467557
SNA3_YEASTSNA3physical
18467557
ENG2_YEASTACF2physical
18467557
ERG7_YEASTERG7physical
18467557
KES1_YEASTKES1physical
18467557
CP51_YEASTERG11physical
18467557
MGLL_YEASTYJU3physical
18467557
GGPPS_YEASTBTS1genetic
21623372
ELO2_YEASTELO2genetic
21623372
VPS24_YEASTVPS24genetic
23891562
SHE1_YEASTSHE1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
ICE2_YEASTICE2genetic
27708008
RAD10_YEASTRAD10genetic
27708008
INO4_YEASTINO4genetic
27708008
VAM3_YEASTVAM3genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
MAK16_YEASTMAK16genetic
27708008
FCF1_YEASTFCF1genetic
27708008
GPI19_YEASTGPI19genetic
27708008
RMRP_YEASTSNM1genetic
27708008
COG3_YEASTCOG3genetic
27708008
MOB2_YEASTMOB2genetic
27708008
ACT_YEASTACT1genetic
27708008
PGTB1_YEASTCDC43genetic
27708008
RRP41_YEASTSKI6genetic
27708008
SDA1_YEASTSDA1genetic
27708008
IPI1_YEASTIPI1genetic
27708008
NU192_YEASTNUP192genetic
27708008
CDC11_YEASTCDC11genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
BOS1_YEASTBOS1genetic
27708008
MED11_YEASTMED11genetic
27708008
VTI1_YEASTVTI1genetic
27708008
ROT1_YEASTROT1genetic
27708008
CUS1_YEASTCUS1genetic
27708008
OST2_YEASTOST2genetic
27708008
SMP3_YEASTSMP3genetic
27708008
GPI2_YEASTGPI2genetic
27708008
NIP7_YEASTNIP7genetic
27708008
PSB5_YEASTPRE2genetic
27708008
CSG2_YEASTCSG2genetic
27708008
ARL1_YEASTARL1genetic
27708008
IMG2_YEASTIMG2genetic
27708008
GEP7_YEASTGEP7genetic
27708008
PHB2_YEASTPHB2genetic
27708008
FSH1_YEASTFSH1genetic
27708008
YJQ3_YEASTYJL163Cgenetic
27708008
HOC1_YEASTHOC1genetic
27708008
CTK1_YEASTCTK1genetic
27708008
ALAM_YEASTALT1genetic
27708008
CDC73_YEASTCDC73genetic
27708008
PKR1_YEASTPKR1genetic
27708008
SFL1_YEASTSFL1genetic
27708008
ALE1_YEASTALE1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PLSC_YEAST

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Related Literatures of Post-Translational Modification

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