dbPTM

ERP3_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ERP3_YEAST
UniProt AC	Q12403
Protein Name	Protein ERP3
Gene Name	ERP3
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	225
Subcellular Localization	Endoplasmic reticulum membrane Single-pass type I membrane protein.
Protein Description	Involved in vesicular protein trafficking..
Protein Sequence	MSNLCVLFFQFFFLAQFFAEASPLTFELNKGRKECLYTLTPEIDCTISYYFAVQQGESNDFDVNYEIFAPDDKNKPIIERSGERQGEWSFIGQHKGEYAICFYGGKAHDKIVDLDFKYNCERQDDIRNERRKARKAQRNLRDSKTDPLQDSVENSIDTIERQLHVLERNIQYYKSRNTRNHHTVCSTEHRIVMFSIYGILLIIGMSCAQIAILEFIFRESRKHNV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
144	Ubiquitination	QRNLRDSKTDPLQDS HHHHHHCCCCHHHHH	62.32	24961812
145	Phosphorylation	RNLRDSKTDPLQDSV HHHHHCCCCHHHHHH	46.96	28889911
174	Ubiquitination	ERNIQYYKSRNTRNH HHHHHHHHCCCCCCC	37.70	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ERP3_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ERP3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ERP3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ERP5_YEAST	ERP5	physical	16429126
RL4A_YEAST	RPL4A	physical	16429126
EMP24_YEAST	EMP24	physical	16429126
TMEDA_YEAST	ERV25	physical	16429126
PST2_YEAST	PST2	genetic	16269340
PLSC_YEAST	SLC1	genetic	16269340
ERP5_YEAST	ERP5	physical	19591838
HSP71_YEAST	SSA1	physical	22940862
KPYK1_YEAST	CDC19	physical	22940862
ERP3_YEAST	ERP3	physical	22940862
PSK1_YEAST	PSK1	physical	22875988
HPH2_YEAST	FRT2	physical	22875988
KIP1_YEAST	KIP1	physical	22875988
ISW1_YEAST	ISW1	physical	22875988
TUP1_YEAST	TUP1	physical	22875988
VPS64_YEAST	VPS64	physical	22875988
GLU2B_YEAST	GTB1	physical	22875988
IVY1_YEAST	IVY1	physical	22875988
HDA2_YEAST	HDA2	physical	22875988
PFD2_YEAST	GIM4	physical	22875988
YEF3_YEAST	YEL043W	physical	22875988
BUD27_YEAST	BUD27	physical	22875988
FMP32_YEAST	FMP32	physical	22875988
NIC96_YEAST	NIC96	physical	22875988
ERP6_YEAST	ERP6	physical	22875988
COG7_YEAST	COG7	physical	22875988
MED3_YEAST	PGD1	physical	22875988
COG2_YEAST	COG2	physical	22875988
OKP1_YEAST	OKP1	physical	22875988
KEL2_YEAST	KEL2	physical	22875988
ERP5_YEAST	ERP5	physical	22875988
KEL1_YEAST	KEL1	physical	22875988
LNP_YEAST	LNP1	physical	22875988
MPS3_YEAST	MPS3	physical	22875988
YJE9_YEAST	YJL049W	physical	22875988
NUP82_YEAST	NUP82	physical	22875988
RE107_YEAST	REC107	physical	22875988
HSK3_YEAST	HSK3	physical	22875988
EBP2_YEAST	EBP2	physical	22875988
DYHC_YEAST	DYN1	physical	22875988
DAD2_YEAST	DAD2	physical	22875988
SED5_YEAST	SED5	physical	22875988
CHA4_YEAST	CHA4	physical	22875988
MMR1_YEAST	MMR1	physical	22875988
NKP2_YEAST	NKP2	physical	22875988
HSP7Q_YEAST	SSQ1	physical	22875988
FMP27_YEAST	FMP27	physical	22875988
MDM1_YEAST	MDM1	physical	22875988
CBF3B_YEAST	CEP3	physical	22875988
END3_YEAST	END3	physical	22875988
CNM67_YEAST	CNM67	physical	22875988
HPH1_YEAST	FRT1	physical	22875988
CTF19_YEAST	CTF19	physical	22875988
YP117_YEAST	YPR117W	physical	22875988
NCA2_YEAST	NCA2	physical	22875988
EMP24_YEAST	EMP24	physical	24217251
TMEDA_YEAST	ERV25	physical	24217251
ERP1_YEAST	ERP1	physical	24217251
ERP5_YEAST	ERP5	physical	24217251
ERP2_YEAST	ERP2	physical	24217251
ERP4_YEAST	ERP4	physical	24217251
RRT6_YEAST	RRT6	physical	24217251
YD514_YEAST	YDR514C	genetic	27708008
RL22A_YEAST	RPL22A	genetic	27708008
UBA3_YEAST	UBA3	genetic	27708008
VPS8_YEAST	VPS8	genetic	27708008
ETR1_YEAST	ETR1	genetic	27708008
ATG12_YEAST	ATG12	genetic	27708008
YCR3_YEAST	YCR023C	genetic	27708008
ATG15_YEAST	ATG15	genetic	27708008
YCZ2_YEAST	YCR102C	genetic	27708008
CAJ1_YEAST	CAJ1	genetic	27708008
YEV1_YEAST	YER121W	genetic	27708008
TAPT1_YEAST	EMP65	genetic	27708008
MSH4_YEAST	MSH4	genetic	27708008
WWM1_YEAST	WWM1	genetic	27708008
DLDH_YEAST	LPD1	genetic	27708008
YFF1_YEAST	YFL051C	genetic	27708008
ATG1_YEAST	ATG1	genetic	27708008
STF2_YEAST	STF2	genetic	27708008
MUP1_YEAST	MUP1	genetic	27708008
HSV2_YEAST	HSV2	genetic	27708008
YG51_YEAST	YGR237C	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
ATG7_YEAST	ATG7	genetic	27708008
YL149_YEAST	YLR149C	genetic	27708008
PFD6_YEAST	YKE2	genetic	27708008
LIPB_YEAST	LIP2	genetic	27708008
TMA10_YEAST	TMA10	genetic	27708008
GLRX8_YEAST	GRX8	genetic	27708008
VAC14_YEAST	VAC14	genetic	27708008
YMK8_YEAST	YML108W	genetic	27708008
GTR1_YEAST	GTR1	genetic	27708008
ATG16_YEAST	ATG16	genetic	27708008
SCS7_YEAST	SCS7	genetic	27708008
PABC_YEAST	ABZ2	genetic	27708008
MKT1_YEAST	MKT1	genetic	27708008
APP1_YEAST	APP1	genetic	27708008
LSM7_YEAST	LSM7	genetic	27708008
ATG3_YEAST	ATG3	genetic	27708008
MSN1_YEAST	MSN1	genetic	27708008
TRM11_YEAST	TRM11	genetic	27708008
HPF1_YEAST	HPF1	genetic	27708008
CYC2_YEAST	CYC2	genetic	27708008
GYP1_YEAST	GYP1	genetic	27708008
ATX2_YEAST	ATX2	genetic	27708008
KTR1_YEAST	KTR1	genetic	27708008
SLK19_YEAST	SLK19	genetic	27708008
LIPA_YEAST	LIP5	genetic	27708008
BRR1_YEAST	BRR1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ERP3_YEAST

Related Literatures of Post-Translational Modification