RE107_YEAST - dbPTM
RE107_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RE107_YEAST
UniProt AC P21651
Protein Name Recombination protein 107
Gene Name REC107
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 314
Subcellular Localization Nucleus . Chromosome . Localizes to chromosomes.
Protein Description Essential for meiotic chromosome segregation. MER1 and MER2 proteins must interact directly or indirectly. MER1 might be responsible for regulating the MER2 gene and/or gene product. MER2 is not required for mitosis and mitotic DNA repair mechanisms. Component of the MER2-MEI4-REC114 complex which seems to be required for meiotic double-strand break (DSB) formation..
Protein Sequence MVARGRTDEISTDVSEANSEHSLMITETSSPFRSIFSHSGKVANAGALEESDKQILEWAGKLELESMELRENSDKLIKVLNENSKTLCKSLNKFNQLLEQDAATNGNVKTLIKDLASQIENQLDKVSTAMLSKGDEKKTKSDSSYRQVLVEEISRYNSKITRHVTNKQHETEKSMRCTQEMLFNVGSQLEDVHKVLLSLSKDMHSLQTRQTALEMAFREKADHAYDRPDVSLNGTTLLHDMDEAHDKQRKKSVPPPRMMVTRSMKRRRSSSPTLSTSQNHNSEDNDDASHRLKRAARTIIPWEELRPDTLESEL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationRGRTDEISTDVSEAN
CCCCCCCCCCHHHHC		19.2628889911
15PhosphorylationDEISTDVSEANSEHS
CCCCCCHHHHCCCCC		33.5328889911
19PhosphorylationTDVSEANSEHSLMIT
CCHHHHCCCCCEEEE		43.6728889911
22PhosphorylationSEANSEHSLMITETS
HHHCCCCCEEEEECC		18.6428889911
29PhosphorylationSLMITETSSPFRSIF
CEEEEECCCCHHHHH		29.7628889911
30PhosphorylationLMITETSSPFRSIFS
EEEEECCCCHHHHHC		35.1628889911
34PhosphorylationETSSPFRSIFSHSGK
ECCCCHHHHHCCCCC		28.5029688323
37PhosphorylationSPFRSIFSHSGKVAN
CCHHHHHCCCCCCCC		18.3127214570
39PhosphorylationFRSIFSHSGKVANAG
HHHHHCCCCCCCCCC		38.8329688323
73PhosphorylationSMELRENSDKLIKVL
HHHHHHCHHHHHHHH		31.2228889911
117PhosphorylationTLIKDLASQIENQLD
HHHHHHHHHHHHHHH		38.7027214570
132PhosphorylationKVSTAMLSKGDEKKT
HHHHHHHCCCCCCCC		22.8519779198
225PhosphorylationREKADHAYDRPDVSL
HHHCCCCCCCCCCCC		14.7427017623
269PhosphorylationRSMKRRRSSSPTLST
HHHHHHHCCCCCCCC		33.1024961812
270PhosphorylationSMKRRRSSSPTLSTS
HHHHHHCCCCCCCCC		38.2324961812
271PhosphorylationMKRRRSSSPTLSTSQ
HHHHHCCCCCCCCCC		24.1328889911
273PhosphorylationRRRSSSPTLSTSQNH
HHHCCCCCCCCCCCC		34.9824961812
275PhosphorylationRSSSPTLSTSQNHNS
HCCCCCCCCCCCCCC		28.6124961812
276PhosphorylationSSSPTLSTSQNHNSE
CCCCCCCCCCCCCCC		37.1324961812
277PhosphorylationSSPTLSTSQNHNSED
CCCCCCCCCCCCCCC		26.1324961812
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
30SPhosphorylationKinaseCDC28P00546
GPS
271SPhosphorylationKinaseCDC28P00546
GPS
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RE107_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RE107_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MEI4_YEASTMEI4physical
14992724
RE107_YEASTREC107physical
14992724
XRS2_YEASTXRS2physical
14992724
RE107_YEASTREC107physical
11967834
HFM1_YEASTHFM1genetic
10523314
MEI4_YEASTMEI4physical
16783010
RE114_YEASTREC114physical
16783010
MAD2_YEASTMAD2genetic
17314980
SLX5_YEASTSLX5genetic
17314980
RE114_YEASTREC114physical
17558514
VAC14_YEASTVAC14physical
18719252
RE107_YEASTREC107physical
22875988
BIK1_YEASTBIK1physical
22875988
CAT8_YEASTCAT8physical
22875988
SPP1_YEASTSPP1physical
23160953
SPP1_YEASTSPP1physical
23246437
KPC1_YEASTPKC1genetic
27708008
CDK1_YEASTCDC28genetic
27708008
TAF12_YEASTTAF12genetic
27708008
NCS1_YEASTFRQ1genetic
27708008
TBP_YEASTSPT15genetic
27708008
PSB7_YEASTPRE4genetic
27708008
BRL1_YEASTBRL1genetic
27708008
NU159_YEASTNUP159genetic
27708008
GPI13_YEASTGPI13genetic
27708008
NOP56_YEASTNOP56genetic
27708008
SEC13_YEASTSEC13genetic
27708008
SEC22_YEASTSEC22genetic
27708008
POB3_YEASTPOB3genetic
27708008
RRP5_YEASTRRP5genetic
27708008
PROF_YEASTPFY1genetic
27708008
MYO2_YEASTMYO2genetic
27708008
TFC8_YEASTTFC8genetic
27708008
ULP1_YEASTULP1genetic
27708008
SEC62_YEASTSEC62genetic
27708008
TSC3_YEASTTSC3genetic
27708008
RPAB1_YEASTRPB5genetic
27708008
MED8_YEASTMED8genetic
27708008
CDC7_YEASTCDC7genetic
27708008
LCB2_YEASTLCB2genetic
27708008
PDC2_YEASTPDC2genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
COPB_YEASTSEC26genetic
27708008
MOB2_YEASTMOB2genetic
27708008
CDC20_YEASTCDC20genetic
27708008
MCE1_YEASTCEG1genetic
27708008
CBF3A_YEASTCBF2genetic
27708008
ORC6_YEASTORC6genetic
27708008
DNA2_YEASTDNA2genetic
27708008
TIM44_YEASTTIM44genetic
27708008
MET30_YEASTMET30genetic
27708008
MAK11_YEASTMAK11genetic
27708008
SN114_YEASTSNU114genetic
27708008
CDC3_YEASTCDC3genetic
27708008
ROT1_YEASTROT1genetic
27708008
LCB1_YEASTLCB1genetic
27708008
LST8_YEASTLST8genetic
27708008
DYR_YEASTDFR1genetic
27708008
ORC4_YEASTORC4genetic
27708008
GMCL1_HUMANGMCL1physical
27107014
GOPC_HUMANGOPCphysical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RE107_YEAST

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Related Literatures of Post-Translational Modification

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