| UniProt ID | GPI13_YEAST | |
|---|---|---|
| UniProt AC | Q07830 | |
| Protein Name | GPI ethanolamine phosphate transferase 3 | |
| Gene Name | GPI13 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1017 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . |
|
| Protein Description | Involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond. Involved in cell wall biosynthesis.. | |
| Protein Sequence | MDEKTIKKSILSSSNDEKIIYKSRIKKFQKNHKFYIILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFAIPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARNDREWSQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKYQKVFLQTCEELWAKFDYYSIATGITLLATSLVLLISITKLIPSIVVNQMVPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADYWSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKRQSTTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGGYHSAVLIIFTRLASMITICREEQGEYCIPTFNNQNNSSWWVLGLCFLMIFILPACITGYYNLTSSYQAAAPIWINVFLKGILGLNFVYWSLTSLENNSAVIAIPFLRDVTIFKFTLARIIAGFSLIASNVGWLMGPLCIKLNIHNTDVKSHEATILGYTNIYGSEFFLLVINVLISILLFNKPLAQLSYFLMCNQLLSILEIIDLLKLKENIIGPIALGLLSYQHFFTTGHQATIPSVQWDIGFMLSEKVTFPFTQIAIILNTFGPHILVSLSVALLTLWSQPPDVLKPQTLLGRIVSNCGILLTYNTILCLSSFIWVTHFRRHLMVWKIFCPRFIFASLSLIVTQLVVTFGTIAFASGRLIKHINDIFWK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 | Acetylation | LSSSNDEKIIYKSRI HCCCCCCCEEEHHHH | 36.95 | 24489116 | |
| 66 | N-linked_Glycosylation | LSRHVLDNISSQNET HHHHHHHHCCCCCCC | 31.70 | - | |
| 71 | N-linked_Glycosylation | LDNISSQNETSKLPP HHHCCCCCCCCCCCC | 57.36 | - | |
| 100 | N-linked_Glycosylation | FDFAIPVNESHSNYN CCEEEECCCCCCCCC | 39.43 | - | |
| 182 | N-linked_Glycosylation | LKQLHLANKTVKFAG HHHHHHCCCEEEECC | 47.06 | - | |
| 203 | N-linked_Glycosylation | LFHPFLSNDSFPLES HHCHHHCCCCCCHHH | 51.60 | - | |
| 411 | N-linked_Glycosylation | ILEPLAKNISNTPPT HHHHHHHHCCCCCCC | 37.00 | - | |
| 418 | Phosphorylation | NISNTPPTSDPEKFV HCCCCCCCCCHHHHH | 47.14 | 28889911 | |
| 419 | Phosphorylation | ISNTPPTSDPEKFVK CCCCCCCCCHHHHHH | 57.87 | 28889911 | |
| 616 | Phosphorylation | ALLTATISEKEGTTS EEEEEEEECCCCCCC | 37.96 | 28889911 | |
| 681 | N-linked_Glycosylation | IPTFNNQNNSSWWVL EECCCCCCCHHHHHH | 53.10 | - | |
| 682 | N-linked_Glycosylation | PTFNNQNNSSWWVLG ECCCCCCCHHHHHHH | 27.88 | - | |
| 707 | N-linked_Glycosylation | ACITGYYNLTSSYQA HHHHCHHCCCCCCCC | 28.49 | - | |
| 742 | N-linked_Glycosylation | WSLTSLENNSAVIAI EEHHHCCCCCEEEEE | 53.72 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GPI13_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GPI13_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GPI13_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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