MUM2_YEAST - dbPTM
MUM2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MUM2_YEAST
UniProt AC P38236
Protein Name Protein MUM2
Gene Name MUM2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 366
Subcellular Localization Cytoplasm . Nucleus, nucleolus . Localizes in the nucleolus during the period of m6A mRNA accumulation.
Protein Description Component of the MIS complex, a complex that mediates N6-methyladenosine (m6A) methylation on some mRNAs during meiosis and is required for sporulation..
Protein Sequence MNYMAYDYDPQHSLETSFNNLAFHPHQQSQQQALYESGERNDARPGLMNTLGQASKMNNSMLPQGSSASPLTGQHSLNSTTNFNMPPSMNTYNYQNVPQASMRNTLNHNNIMNGATANDYWLDPMNNMTNNKDTNGNPNDSMSSMSNMTAKTSINSTAFKNSFVPFNHVTALSMNNVNSNEMNSNKDDRMEALEVELQIKESQIESLENEIQRLKKIFNEGLNYKQNEHKYEKENCHIPQTFELPASLEVIFRKLSSSLHAKEKELAETKENLESILTALALNPTNSVTKYGRYDAESIAHKMVVRLENLTNENKEMAKMLAYGRSKETQIELQLAKKENLELREKIASLEAHLASKESSKEDVAN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
134PhosphorylationNMTNNKDTNGNPNDS
CCCCCCCCCCCCCCC
46.7819795423
141PhosphorylationTNGNPNDSMSSMSNM
CCCCCCCCCHHHHHH
27.4919823750
143PhosphorylationGNPNDSMSSMSNMTA
CCCCCCCHHHHHHCC
27.1719823750
144PhosphorylationNPNDSMSSMSNMTAK
CCCCCCHHHHHHCCC
20.0019823750
146PhosphorylationNDSMSSMSNMTAKTS
CCCCHHHHHHCCCCC
25.9519823750
149PhosphorylationMSSMSNMTAKTSINS
CHHHHHHCCCCCCCC
29.2919823750

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MUM2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MUM2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MUM2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YG036_YEASTYGL036Wphysical
11805826
SPO14_YEASTSPO14physical
11805826
DPOA_YEASTPOL1genetic
11238403
VPS13_YEASTVPS13physical
16554755
DEP1_YEASTDEP1genetic
17314980
MUM2_YEASTMUM2physical
18467557
IME4_YEASTIME4physical
22685417
HPH2_YEASTFRT2physical
22875988
PRP45_YEASTPRP45physical
22875988
KIP1_YEASTKIP1physical
22875988
MUM2_YEASTMUM2physical
22875988
RXT2_YEASTRXT2physical
22875988
EXO84_YEASTEXO84physical
22875988
ATG14_YEASTATG14physical
22875988
SGF29_YEASTSGF29physical
22875988
NOP14_YEASTNOP14physical
22875988
SAC3_YEASTSAC3physical
22875988
SCC2_YEASTSCC2physical
22875988
REF2_YEASTREF2physical
22875988
VPS64_YEASTVPS64physical
22875988
IVY1_YEASTIVY1physical
22875988
YAP6_YEASTYAP6physical
22875988
HDA2_YEASTHDA2physical
22875988
SP110_YEASTSPC110physical
22875988
SNX41_YEASTSNX41physical
22875988
LRS4_YEASTLRS4physical
22875988
ECM11_YEASTECM11physical
22875988
VPS52_YEASTVPS52physical
22875988
PSP1_YEASTPSP1physical
22875988
KRE28_YEASTKRE28physical
22875988
VAB2_YEASTVAB2physical
22875988
YEF3_YEASTYEL043Wphysical
22875988
SPC25_YEASTSPC25physical
22875988
TSC11_YEASTTSC11physical
22875988
VFA1_YEASTVFA1physical
22875988
MED3_YEASTPGD1physical
22875988
MPS2_YEASTMPS2physical
22875988
MAD1_YEASTMAD1physical
22875988
SP105_YEASTSPC105physical
22875988
VAM7_YEASTVAM7physical
22875988
RTF1_YEASTRTF1physical
22875988
NUP57_YEASTNUP57physical
22875988
COG2_YEASTCOG2physical
22875988
YG3A_YEASTYGR130Cphysical
22875988
CCM1_YEASTCCM1physical
22875988
OKP1_YEASTOKP1physical
22875988
KEL2_YEASTKEL2physical
22875988
HSE1_YEASTHSE1physical
22875988
RPN1_YEASTRPN1physical
22875988
SAE3_YEASTSAE3physical
22875988
MSH1_YEASTMSH1physical
22875988
KEL1_YEASTKEL1physical
22875988
TDA11_YEASTTDA11physical
22875988
LNP_YEASTLNP1physical
22875988
SKN7_YEASTSKN7physical
22875988
OM45_YEASTOM45physical
22875988
NDC80_YEASTNDC80physical
22875988
YJE9_YEASTYJL049Wphysical
22875988
LAA1_YEASTLAA1physical
22875988
ACF4_YEASTACF4physical
22875988
ATP7_YEASTATP7physical
22875988
VATC_YEASTVMA5physical
22875988
EBP2_YEASTEBP2physical
22875988
CASP_YEASTCOY1physical
22875988
NTR2_YEASTNTR2physical
22875988
DYHC_YEASTDYN1physical
22875988
SNF7_YEASTSNF7physical
22875988
YL031_YEASTYLR031Wphysical
22875988
SRN2_YEASTSRN2physical
22875988
SEC10_YEASTSEC10physical
22875988
NKP2_YEASTNKP2physical
22875988
BL1S1_YEASTBLS1physical
22875988
PFD5_YEASTGIM5physical
22875988
NU188_YEASTNUP188physical
22875988
MDM1_YEASTMDM1physical
22875988
BUL2_YEASTBUL2physical
22875988
STB2_YEASTSTB2physical
22875988
VPS20_YEASTVPS20physical
22875988
CBF3B_YEASTCEP3physical
22875988
TOP2_YEASTTOP2physical
22875988
PFD4_YEASTGIM3physical
22875988
RM50_YEASTMRPL50physical
22875988
CTR9_YEASTCTR9physical
22875988
YO223_YEASTDSC3physical
22875988
PRS10_YEASTRPT4physical
22875988
LIS1_YEASTPAC1physical
22875988
YO304_YEASTBIL1physical
22875988
RPA1_YEASTRPA190physical
22875988
ULP1_YEASTULP1physical
22875988
TBP6_YEASTYTA6physical
22875988
HSP7F_YEASTSSE1physical
22875988
SPP1_YEASTSPP1physical
22875988
IQG1_YEASTIQG1physical
22875988
GYP5_YEASTGYP5physical
22875988
NOT5_YEASTNOT5physical
22875988
YP117_YEASTYPR117Wphysical
22875988
NCA2_YEASTNCA2physical
22875988
YP174_YEASTYPR174Cphysical
22875988
YAP8_YEASTARR1physical
22875988
TGS1_YEASTTGS1genetic
27708008
GPI19_YEASTGPI19genetic
27708008
FIP1_YEASTFIP1genetic
27708008
MED11_YEASTMED11genetic
27708008
GPI12_YEASTGPI12genetic
27708008
NOP2_YEASTNOP2genetic
27708008
NIP7_YEASTNIP7genetic
27708008
ARP7_YEASTARP7genetic
27708008
UME6_YEASTUME6genetic
27708008
PMP3_YEASTPMP3genetic
27708008
SDS23_YEASTSDS23genetic
27708008
DSD1_YEASTDSD1genetic
27708008
FEN1_YEASTRAD27genetic
27708008
RL40A_YEASTRPL40Bgenetic
27708008
RL40B_YEASTRPL40Bgenetic
27708008
FMP25_YEASTFMP25genetic
27708008
SWI6_YEASTSWI6genetic
27708008
EIF3J_YEASTHCR1genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
RSF1_YEASTRSF1genetic
27708008
EOS1_YEASTEOS1genetic
27708008
YNL5_YEASTYNL115Cgenetic
27708008
CTU2_YEASTNCS2genetic
27708008
RTC1_YEASTRTC1genetic
27708008
RMI1_YEASTRMI1genetic
27708008
SKS1_YEASTSKS1genetic
27708008
NACB1_YEASTEGD1genetic
27708008
RTC6_YEASTRTC6genetic
27708008
ETFA_YEASTAIM45genetic
27708008
YP114_YEASTYPR114Wgenetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MUM2_YEAST

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Related Literatures of Post-Translational Modification

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