dbPTM

VAB2_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VAB2_YEAST
UniProt AC	P40003
Protein Name	Biogenesis of lysosome-related organelles complex 1 subunit VAB2
Gene Name	VAB2
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	282
Subcellular Localization	Cytoplasmic vesicle . Cytoplasm . Vacuole .
Protein Description	Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting..
Protein Sequence	MVADLTKGILKWKSRIEFDAVGSSSYYEELKGLPPLASHKKLTQAAIFNSTKYELLQVKKDILSIYEVVSRDIDEERNQMQQIELQLKKSLKKVEHSYKNVLKQRASTNCINGNDRLLANAEKKIGSLNEELACVNDIVSDIVNNLTALNANLPKKAQLLKDDSINVAHYPLLFDFLHKSCPKSIIATSEASIHENASPSPLLEHDELPAESINSFYGENELQSDSLAPLQTHDDNISSCKKILPPKFNTTSGPSIETNFENISADGLTYTKCSLKNSISLT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
107	Phosphorylation	NVLKQRASTNCINGN HHHHHHHCCCCCCCC	23.49	21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VAB2_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VAB2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VAB2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VAC8_YEAST	VAC8	physical	10888680
BL1S4_YEAST	CNL1	physical	16554755
KXD1_YEAST	KXD1	physical	16554755
BL1S1_YEAST	BLS1	physical	16554755
SNAPN_YEAST	SNN1	physical	16554755
ATC1_YEAST	PMR1	genetic	16269340
SUR2_YEAST	SUR2	genetic	16269340
KXD1_YEAST	KXD1	physical	11283351
SNAPN_YEAST	SNN1	physical	11283351
KXD1_YEAST	KXD1	physical	23547030
BL1S4_YEAST	CNL1	physical	23547030
BL1S1_YEAST	BLS1	physical	23547030
BLI1_YEAST	BLI1	physical	23547030
SNAPN_YEAST	SNN1	physical	23547030
VAC8_YEAST	VAC8	physical	23547030
GYP3_YEAST	MSB3	physical	23547030
CDC1_YEAST	CDC1	genetic	27708008
STU1_YEAST	STU1	genetic	27708008
ARP2_YEAST	ARP2	genetic	27708008
TCPD_YEAST	CCT4	genetic	27708008
TAF12_YEAST	TAF12	genetic	27708008
TCPZ_YEAST	CCT6	genetic	27708008
TCPA_YEAST	TCP1	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
ARPC5_YEAST	ARC15	genetic	27708008
ARP4_YEAST	ARP4	genetic	27708008
TCPE_YEAST	CCT5	genetic	27708008
MED14_YEAST	RGR1	genetic	27708008
SMC4_YEAST	SMC4	genetic	27708008
RSC9_YEAST	RSC9	genetic	27708008
ARPC2_YEAST	ARC35	genetic	27708008
PROF_YEAST	PFY1	genetic	27708008
RPB2_YEAST	RPB2	genetic	27708008
ASA1_YEAST	ASA1	genetic	27708008
BLI1_YEAST	BLI1	physical	25971802
SNAPN_YEAST	SNN1	physical	25971802

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VAB2_YEAST

Related Literatures of Post-Translational Modification