dbPTM

KXD1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KXD1_YEAST
UniProt AC	P53158
Protein Name	Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Gene Name	KXD1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	218
Subcellular Localization	Endosome .
Protein Description	Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting..
Protein Sequence	MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
119	Phosphorylation	IFDSLKQSIDSADFS HHHHHHHHHCCCCHH	27.12	20377248
122	Phosphorylation	SLKQSIDSADFSEAL HHHHHHCCCCHHHHH	28.24	20377248
126	Phosphorylation	SIDSADFSEALSLQT HHCCCCHHHHHCCHH	23.62	20377248
133	Phosphorylation	SEALSLQTKTSAVIN HHHHCCHHHHCHHHC	41.40	20377248

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KXD1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KXD1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KXD1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EXO84_YEAST	EXO84	physical	22875988
BL1S4_YEAST	CNL1	physical	22875988
NNF1_YEAST	NNF1	physical	22875988
BLI1_YEAST	BLI1	physical	22875988
END3_YEAST	END3	physical	22875988
RPAC2_YEAST	RPC19	physical	22875988
BL1S1_YEAST	BLS1	physical	22875988
SPC24_YEAST	SPC24	physical	22875988
VAB2_YEAST	VAB2	physical	23547030
SNAPN_YEAST	SNN1	physical	23547030
BL1S1_YEAST	BLS1	physical	23547030
BLI1_YEAST	BLI1	physical	23547030
BL1S4_YEAST	CNL1	physical	23547030
RL37A_YEAST	RPL37A	genetic	27708008
ECM8_YEAST	ECM8	genetic	27708008
CCZ1_YEAST	CCZ1	genetic	27708008
MET8_YEAST	MET8	genetic	27708008
RV161_YEAST	RVS161	genetic	27708008
TAH1_YEAST	TAH1	genetic	27708008
BUD31_YEAST	BUD31	genetic	27708008
CWC15_YEAST	CWC15	genetic	27708008
PMP3_YEAST	PMP3	genetic	27708008
RV167_YEAST	RVS167	genetic	27708008
MZM1_YEAST	MZM1	genetic	27708008
MSRA_YEAST	MXR1	genetic	27708008
CEM1_YEAST	CEM1	genetic	27708008
RAD4_YEAST	RAD4	genetic	27708008
WWM1_YEAST	WWM1	genetic	27708008
NPR3_YEAST	NPR3	genetic	27708008
SLT2_YEAST	SLT2	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
ATG7_YEAST	ATG7	genetic	27708008
BCK1_YEAST	BCK1	genetic	27708008
MBR1_YEAST	MBR1	genetic	27708008
YKK0_YEAST	YPF1	genetic	27708008
PMU1_YEAST	PMU1	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
RSSA2_YEAST	RPS0B	genetic	27708008
ECM19_YEAST	ECM19	genetic	27708008
PSP2_YEAST	PSP2	genetic	27708008
RAD14_YEAST	RAD14	genetic	27708008
LSM7_YEAST	LSM7	genetic	27708008
ATG3_YEAST	ATG3	genetic	27708008
PHO80_YEAST	PHO80	genetic	27708008
VPS5_YEAST	VPS5	genetic	27708008
LIPA_YEAST	LIP5	genetic	27708008
PMA2_YEAST	PMA2	genetic	27708008
TBP6_YEAST	YTA6	genetic	27708008
WDR6_YEAST	RTT10	genetic	27708008
OPT2_YEAST	OPT2	genetic	27708008
BL1S4_YEAST	CNL1	physical	25971802
YPT7_YEAST	YPT7	physical	25971802

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KXD1_YEAST

Related Literatures of Post-Translational Modification