PMU1_YEAST - dbPTM
PMU1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PMU1_YEAST
UniProt AC P36069
Protein Name Probable phosphoglycerate mutase PMU1
Gene Name PMU1 {ECO:0000303|PubMed:8913738}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 295
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Probable phosphomutase that may have a function related to the manipulation of phosphate groups on carbohydrates. Reduces trehalose-6-phosphate levels when overexpressed in TPS2-deleted cells. Reduces 5'-Phosphoribosyl-4-carboxamide-5-aminoimidazole (AICAR) levels, a metabolic intermediate at the crossroads between AMP and histidine biosynthesis pathways, when overexpressed in a ADE3-ADE16-ADE17 triple deletant..
Protein Sequence MSLRAVPGYFAAYPSEGFQGLDSTKYDHLELINHKNWKELYHAIPRNTKNRHYKLLILARHGQGYHNAAILRYGMEKWDAYWSLLSGDEHGEWLDSKLTPLGKDQVRRTGSNVLLPMAKQLGMLPHVFFSSPMRRCLETFIESWTPVLAETQELPAGTKISTRIIEGLRETLGSHTCDKRVAHSMAVDEYQDFSTESGHTVHWQYVPDYPEDDELWLPDHRETCAEMDKRTLNGLFELFNQLSSEEKFISLTCHSGVIQSVLRNLQHPPIYNLDTGKVVAVVVEVPVNTADRGRL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
38AcetylationLINHKNWKELYHAIP
HHCCCCHHHHHHHCC		47.4324489116
111PhosphorylationDQVRRTGSNVLLPMA
HHHHHHCCCCHHHHH		24.1321440633
179UbiquitinationLGSHTCDKRVAHSMA
HCCCCCCHHHHHHHC		51.4223749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PMU1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PMU1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PMU1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VHR2_YEASTVHR2physical
16554755
YTA12_YEASTYTA12physical
16554755
KPC1_YEASTPKC1genetic
27708008
APC11_YEASTAPC11genetic
27708008
PRP9_YEASTPRP9genetic
27708008
KIN28_YEASTKIN28genetic
27708008
GLE1_YEASTGLE1genetic
27708008
LCB2_YEASTLCB2genetic
27708008
TAF12_YEASTTAF12genetic
27708008
STT3_YEASTSTT3genetic
27708008
CDC12_YEASTCDC12genetic
27708008
MCM10_YEASTMCM10genetic
27708008
DPB11_YEASTDPB11genetic
27708008
CDC11_YEASTCDC11genetic
27708008
TAD3_YEASTTAD3genetic
27708008
VTI1_YEASTVTI1genetic
27708008
LCB1_YEASTLCB1genetic
27708008
CH10_YEASTHSP10genetic
27708008
TYSY_YEASTCDC21genetic
27708008
NAB3_YEASTNAB3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PMU1_YEAST

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Related Literatures of Post-Translational Modification

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