dbPTM

VHR2_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VHR2_YEAST
UniProt AC	P40041
Protein Name	Transcription factor VHR2
Gene Name	VHR2
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	505
Subcellular Localization	Nucleus .
Protein Description	Transcription factor that regulates ERG9, but seems to have a more global function in transcription..
Protein Sequence	MIDDTENSKIHLEGSHKTGKYTGYGTTHKIRAQLNFNDEKKWKKFSSRRLELIDSFGLSQHKASEQDDNIRQIATILRSEFEYPDTFSAEFEKLVTAAVQSVRRNRKRSKKKLLDSKKKIARGKVQKIPLSPPSSSNMGSCSASNASSSDEEASVKEEPAEHALPSLNTITSQKLLPYPNGRTLPPVPTQVRSLLKKNASLLRDPSAPYAHGGDEKLQKFDIEDQPLESEQEYDFIAKSIIVEIVNNAIPLPEQIQRDKFIRPNLTKKKGCQSKVVISNNLRKLILSKIHNSRTCLEMSKDERNLDSFANLETLGKNSLMASISLVVENSFSHLPSSTKQYLTERLSSIEFLTILSQRLFMPATRQLFADLSQEKIQVRVLNLILGSLVKDYGFDASLAPINEIIYHMTLHQYPLVCSNKQSNPMRPHSTSEVLSAHSSTKDASTPGKEEPRVTRSSTSADSTIITLPSIEVPNTYDDDRLKMLSAISLQIENSTFSKPFSTISK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
445	Phosphorylation	SSTKDASTPGKEEPR CCCCCCCCCCCCCCC		23749301
459	Phosphorylation	RVTRSSTSADSTIIT CCCCCCCCCCCEEEE		21440633

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VHR2_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VHR2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VHR2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GNA1_YEAST	GNA1	genetic	27708008
STU1_YEAST	STU1	genetic	27708008
MAK5_YEAST	MAK5	genetic	27708008
RPN6_YEAST	RPN6	genetic	27708008
GPI8_YEAST	GPI8	genetic	27708008
MED6_YEAST	MED6	genetic	27708008
SSL1_YEAST	SSL1	genetic	27708008
CDC91_YEAST	GAB1	genetic	27708008
UTP15_YEAST	UTP15	genetic	27708008
PRS10_YEAST	RPT4	genetic	27708008
GPN2_YEAST	GPN2	genetic	27708008
DIB1_YEAST	DIB1	genetic	27708008
TF2B_YEAST	SUA7	genetic	27708008
ORC4_YEAST	ORC4	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VHR2_YEAST

Related Literatures of Post-Translational Modification