OM45_YEAST - dbPTM
OM45_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID OM45_YEAST
UniProt AC P16547
Protein Name Mitochondrial outer membrane protein OM45
Gene Name OM45
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 393
Subcellular Localization Mitochondrion outer membrane .
Protein Description
Protein Sequence MSSRIIVGSAALAAAITASIMVREQKAKGQRREGNVSAYYNGQEYGSSAPPQLGKLHNIKQGIKEDALSLKDALLGVSQKAREEAPKVTKRVISPEEDAQTRKQLGQKAKDSSSQSIFNWGFSEAERRKAIAIGEFDTAKKRFEEAVDRNEKELLSTVMREKKAALDRASIEYERYGRARDFNELSDKLDQQERNSNPLKRLLKNNTGDANTEEAAARSVQGWGDTAQEFGREELEEAKRNASSEPSEAQKRLDELKKIKEKGWFGYNKGEQSEQQIAERVARGLEGWGETAAQLSKDEMDDLRWNYENSKKQLDKNVSDAMDSLSKAKEDLKQYGSHWWSGWTSKVDNDKQALKDEAQKKYDEALKKYDEAKNKFKEWNDKGDGKFWSSKKD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSSRIIVGS
------CCCCHHHHH		28.4630377154
9PhosphorylationSSRIIVGSAALAAAI
CCCHHHHHHHHHHHH		10.2421126336
19PhosphorylationLAAAITASIMVREQK
HHHHHHHHHHHHHHH		11.5428132839
55AcetylationSAPPQLGKLHNIKQG
CCCCCHHHHCCCCCC		55.9824489116
78PhosphorylationKDALLGVSQKAREEA
HHHHHHHCHHHHHHC		24.9427214570
94PhosphorylationKVTKRVISPEEDAQT
CCCCCCCCHHHHHHH		24.3327214570
114PhosphorylationQKAKDSSSQSIFNWG
HHHCCCCCCCHHHCC		31.7227017623
116PhosphorylationAKDSSSQSIFNWGFS
HCCCCCCCHHHCCCC		30.9727017623
123PhosphorylationSIFNWGFSEAERRKA
CHHHCCCCHHHHHHH		31.7727017623
170PhosphorylationKAALDRASIEYERYG
HHHHHHHHHHHHHHC		19.4921440633
188AcetylationDFNELSDKLDQQERN
CHHHHHHHHHHHHHH		51.0624489116
204AcetylationNPLKRLLKNNTGDAN
CHHHHHHHCCCCCCC		53.3925381059
207PhosphorylationKRLLKNNTGDANTEE
HHHHHCCCCCCCHHH		45.9222369663
244PhosphorylationEAKRNASSEPSEAQK
HHHHHCCCCCHHHHH		51.6328889911
273PhosphorylationGYNKGEQSEQQIAER
CCCCCCHHHHHHHHH		32.8221126336
324PhosphorylationNVSDAMDSLSKAKED
HHHHHHHHHHHHHHH		22.8128889911
326PhosphorylationSDAMDSLSKAKEDLK
HHHHHHHHHHHHHHH		34.2228889911
3512-HydroxyisobutyrylationTSKVDNDKQALKDEA
HCCCCCHHHHHHHHH		43.66-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of OM45_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of OM45_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of OM45_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VDAC1_YEASTPOR1physical
22461620
OM14_YEASTOM14physical
22461620
OM45_YEASTOM45physical
22940862
HSP71_YEASTSSA1physical
22940862
SPO14_YEASTSPO14physical
22875988
VDAC1_YEASTPOR1physical
22142226
TOM20_YEASTTOM20physical
22142226
TOM70_YEASTTOM70physical
22142226
OM14_YEASTOM14physical
24781695
VDAC1_YEASTPOR1physical
24781695
CAB5_YEASTCAB5genetic
27708008
POP7_YEASTPOP7genetic
27708008
CDC10_YEASTCDC10genetic
27708008
CDC1_YEASTCDC1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
CDC23_YEASTCDC23genetic
27708008
KTHY_YEASTCDC8genetic
27708008
ARP3_YEASTARP3genetic
27708008
PRP19_YEASTPRP19genetic
27708008
NOP56_YEASTNOP56genetic
27708008
MCM1_YEASTMCM1genetic
27708008
NOG2_YEASTNOG2genetic
27708008
ATP6_YEASTATP6genetic
28986220
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of OM45_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-170 AND THR-207, ANDMASS SPECTROMETRY.

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