| UniProt ID | NOG2_YEAST | |
|---|---|---|
| UniProt AC | P53742 | |
| Protein Name | Nucleolar GTP-binding protein 2 | |
| Gene Name | NOG2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 486 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.. | |
| Protein Sequence | MGTGKKEKSRRIREGDTKDGNLRVKGENFYRDSKRVKFLNMYTSGKEIRNKKGNLIRAASFQDSTIPDARVQPDRRWFGNTRVISQDALQHFRSALGETQKDTYQVLLRRNKLPMSLLEEKDADESPKARILDTESYADAFGPKAQRKRPRLAASNLEDLVKATNEDITKYEEKQVLDATLGLMGNQEDKENGWTSAAKEAIFSKGQSKRIWNELYKVIDSSDVVIHVLDARDPLGTRCKSVEEYMKKETPHKHLIYVLNKCDLVPTWVAAAWVKHLSKERPTLAFHASITNSFGKGSLIQLLRQFSQLHTDRKQISVGFIGYPNTGKSSIINTLRKKKVCQVAPIPGETKVWQYITLMKRIFLIDCPGIVPPSSKDSEEDILFRGVVRVEHVTHPEQYIPGVLKRCQVKHLERTYEISGWKDATEFIEILARKQGRLLKGGEPDESGVSKQILNDFNRGKIPWFVLPPEKEGEEKPKKKEVEKTA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 | Acetylation | RIREGDTKDGNLRVK CCCCCCCCCCCEEEC | 69.27 | 25381059 | |
| 25 | Acetylation | KDGNLRVKGENFYRD CCCCEEECCEECCCC | 54.82 | 25381059 | |
| 37 | Acetylation | YRDSKRVKFLNMYTS CCCCCCEEEEEECCC | 48.44 | 25381059 | |
| 46 | Acetylation | LNMYTSGKEIRNKKG EEECCCCHHHHCCCC | 50.14 | 24489116 | |
| 60 | Phosphorylation | GNLIRAASFQDSTIP CCEEEEECCCCCCCC | 23.58 | 22369663 | |
| 64 | Phosphorylation | RAASFQDSTIPDARV EEECCCCCCCCCCCC | 19.90 | 22369663 | |
| 65 | Phosphorylation | AASFQDSTIPDARVQ EECCCCCCCCCCCCC | 44.83 | 22369663 | |
| 85 | Phosphorylation | FGNTRVISQDALQHF CCCEEEECHHHHHHH | 21.10 | 22369663 | |
| 94 | Phosphorylation | DALQHFRSALGETQK HHHHHHHHHCCCCCH | 27.23 | 30377154 | |
| 112 | Acetylation | QVLLRRNKLPMSLLE HHHHHCCCCCHHHHC | 52.75 | 24489116 | |
| 116 | Phosphorylation | RRNKLPMSLLEEKDA HCCCCCHHHHCCCCC | 28.06 | 27017623 | |
| 126 | Phosphorylation | EEKDADESPKARILD CCCCCCCCCCCEEEC | 32.04 | 21440633 | |
| 136 | Phosphorylation | ARILDTESYADAFGP CEEECHHHHHHHHCH | 27.93 | 27214570 | |
| 144 | Ubiquitination | YADAFGPKAQRKRPR HHHHHCHHHHHHCCC | 58.49 | 23749301 | |
| 155 | Phosphorylation | KRPRLAASNLEDLVK HCCCHHHCCHHHHHH | 36.02 | 24909858 | |
| 162 | Ubiquitination | SNLEDLVKATNEDIT CCHHHHHHHHHHCCH | 57.71 | 17644757 | |
| 170 | Ubiquitination | ATNEDITKYEEKQVL HHHHCCHHHHHHHHH | 51.50 | 17644757 | |
| 296 | Ubiquitination | SITNSFGKGSLIQLL EECCCCCCHHHHHHH | 43.23 | 15699485 | |
| 314 | Ubiquitination | SQLHTDRKQISVGFI HHHCCCCCCEEEEEE | 55.59 | 15699485 | |
| 328 | Ubiquitination | IGYPNTGKSSIINTL ECCCCCCCCHHHHHH | 38.70 | 15699485 | |
| 338 | Ubiquitination | IINTLRKKKVCQVAP HHHHHCCCCCEEECC | 43.96 | 17644757 | |
| 339 | Ubiquitination | INTLRKKKVCQVAPI HHHHCCCCCEEECCC | 51.80 | 17644757 | |
| 351 | Ubiquitination | APIPGETKVWQYITL CCCCCCCHHHHHHHH | 36.85 | 17644757 | |
| 360 | Ubiquitination | WQYITLMKRIFLIDC HHHHHHHHEEEEECC | 45.51 | 17644757 | |
| 376 | Ubiquitination | GIVPPSSKDSEEDIL CCCCCCCCCCHHHCE | 70.39 | 17644757 | |
| 405 | Ubiquitination | QYIPGVLKRCQVKHL HHCCCHHHHHHEEEE | 49.04 | 17644757 | |
| 422 | Ubiquitination | TYEISGWKDATEFIE EEEECCCCCHHHHHH | 40.80 | 17644757 | |
| 434 | Ubiquitination | FIEILARKQGRLLKG HHHHHHHHCCCCCCC | 52.04 | 17644757 | |
| 447 | Phosphorylation | KGGEPDESGVSKQIL CCCCCCCCCCCHHHH | 52.45 | 27017623 | |
| 451 | Acetylation | PDESGVSKQILNDFN CCCCCCCHHHHHCCC | 38.66 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NOG2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NOG2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NOG2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-60; SER-85 AND SER-155,AND MASS SPECTROMETRY. | |
