| UniProt ID | NHP2_YEAST | |
|---|---|---|
| UniProt AC | P32495 | |
| Protein Name | H/ACA ribonucleoprotein complex subunit NHP2 | |
| Gene Name | NHP2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 156 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. [PubMed: 9843512] | |
| Protein Sequence | MGKDNKEHKESKESKTVDNYEARMPAVLPFAKPLASKKLNKKVLKTVKKASKAKNVKRGVKEVVKALRKGEKGLVVIAGDISPADVISHIPVLCEDHSVPYIFIPSKQDLGAAGATKRPTSVVFIVPGSNKKKDGKNKEEEYKESFNEVVKEVQAL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 15 | Acetylation | HKESKESKTVDNYEA HHHCCCCCCCCCHHH | 54.37 | 24489116 | |
| 16 | Phosphorylation | KESKESKTVDNYEAR HHCCCCCCCCCHHHH | 42.23 | 26447709 | |
| 20 | Phosphorylation | ESKTVDNYEARMPAV CCCCCCCHHHHCCHH | 13.40 | 26447709 | |
| 32 | Ubiquitination | PAVLPFAKPLASKKL CHHHHHHHHHCCHHC | 40.73 | 23749301 | |
| 36 | Phosphorylation | PFAKPLASKKLNKKV HHHHHHCCHHCCHHH | 37.70 | 28889911 | |
| 117 | Acetylation | LGAAGATKRPTSVVF CCCCCCCCCCCEEEE | 56.71 | 24489116 | |
| 120 | Phosphorylation | AGATKRPTSVVFIVP CCCCCCCCEEEEEEC | 37.88 | 21440633 | |
| 121 | Phosphorylation | GATKRPTSVVFIVPG CCCCCCCEEEEEECC | 20.97 | 20377248 | |
| 129 | Phosphorylation | VVFIVPGSNKKKDGK EEEEECCCCCCCCCC | 39.13 | 21440633 | |
| 138 | Acetylation | KKKDGKNKEEEYKES CCCCCCCHHHHHHHH | 70.73 | 24489116 | |
| 143 | Acetylation | KNKEEEYKESFNEVV CCHHHHHHHHHHHHH | 50.60 | 24489116 | |
| 145 | Phosphorylation | KEEEYKESFNEVVKE HHHHHHHHHHHHHHH | 29.26 | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NHP2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NHP2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NHP2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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