dbPTM

UTP13_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UTP13_YEAST
UniProt AC	Q05946
Protein Name	U3 small nucleolar RNA-associated protein 13
Gene Name	UTP13
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	817
Subcellular Localization	Nucleus, nucleolus .
Protein Description	Involved in nucleolar processing of pre-18S ribosomal RNA..
Protein Sequence	MDLKTSYKGISLNPIYAGSSAVATVSENGKILATPVLDEINIIDLTPGSRKILHKISNEDEQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKISSPSYILDADSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKIWLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIINLWDFNMKKKCKLLKTLPVNQQVESCGFLKDGDGKRIIYTAGGDAIFQLIDSESGSVLKRTNKPIEELFIIGVLPILSNSQMFLVLSDQTLQLINVEEDLKNDEDTIQVTSSIAGNHGIIADMRYVGPELNKLALATNSPSLRIIPVPDLSGPEASLPLDVEIYEGHEDLLNSLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPNIVSKGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQFWKDCTEQEIEEEQEKAKLQVEQEQSLQNYMSKGDWTNAFLLAMTLDHPMRLFNVLKRALGESRSRQDTEEGKIEVIFNEELDQAISILNDEQLILLMKRCRDWNTNAKTHTIAQRTIRCILMHHNIAKLSEIPGMVKIVDAIIPYTQRHFTRVDNLVEQSYILDYALVEMDKLF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
352	Ubiquitination	YVGPELNKLALATNS ECCHHHHHHHHHCCC	48.00	23749301
357	Phosphorylation	LNKLALATNSPSLRI HHHHHHHCCCCCEEE	36.76	28889911
359	Phosphorylation	KLALATNSPSLRIIP HHHHHCCCCCEEEEE	16.12	22369663
492	Acetylation	YTRHAHEKDINALSV CCCCCCCCCCCCEEC	54.78	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UTP13_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UTP13_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UTP13_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UTP21_YEAST	UTP21	physical	14759368
UTP18_YEAST	UTP18	physical	14759368
UTP12_YEAST	DIP2	physical	14759368
PWP2_YEAST	PWP2	physical	14759368
UTP6_YEAST	UTP6	physical	14759368
UTP13_YEAST	UTP13	physical	14759368
UTP18_YEAST	UTP18	physical	11805837
UTP12_YEAST	DIP2	physical	11805837
FET4_YEAST	FET4	physical	11805837
YHI0_YEAST	YHR020W	physical	11805837
ARP10_YEAST	ARP10	physical	11805837
PGM2_YEAST	PGM2	physical	11805837
DIP5_YEAST	DIP5	physical	11805837
VDAC1_YEAST	POR1	physical	11805837
MUM2_YEAST	MUM2	physical	11805837
VATA_YEAST	VMA1	physical	11805837
CAP_YEAST	SRV2	physical	11805837
MPP10_YEAST	MPP10	physical	12068309
MRX5_YEAST	YJL147C	physical	16554755
UTP12_YEAST	DIP2	physical	16554755
UTP21_YEAST	UTP21	physical	16554755
COQ2_YEAST	COQ2	physical	11283351
UTP8_YEAST	UTP8	physical	17634288
GBP2_YEAST	GBP2	genetic	19061648
MSN5_YEAST	MSN5	genetic	19061648
SSB1_YEAST	SSB1	physical	19536198
UTP12_YEAST	DIP2	physical	18725399
PXR1_YEAST	PXR1	physical	24823796
CDC48_YEAST	CDC48	genetic	27708008
MOB1_YEAST	MOB1	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
RPC6_YEAST	RPC34	genetic	27708008
SEC12_YEAST	SEC12	genetic	27708008
INO2_YEAST	INO2	genetic	27708008
DPOA2_YEAST	POL12	genetic	27708008
CDC27_YEAST	CDC27	genetic	27708008
SLI15_YEAST	SLI15	genetic	27708008
ENP1_YEAST	ENP1	genetic	27708008
KRR1_YEAST	KRR1	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
PRP9_YEAST	PRP9	genetic	27708008
RRP42_YEAST	RRP42	genetic	27708008
NOP14_YEAST	NOP14	genetic	27708008
NHP2_YEAST	NHP2	genetic	27708008
FAL1_YEAST	FAL1	genetic	27708008
RRP1_YEAST	RRP1	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
GPI8_YEAST	GPI8	genetic	27708008
FCF1_YEAST	FCF1	genetic	27708008
TFC6_YEAST	TFC6	genetic	27708008
UTP5_YEAST	UTP5	genetic	27708008
GPI19_YEAST	GPI19	genetic	27708008
UTP6_YEAST	UTP6	genetic	27708008
RMRP_YEAST	SNM1	genetic	27708008
SCC4_YEAST	SCC4	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
HSF_YEAST	HSF1	genetic	27708008
CDC20_YEAST	CDC20	genetic	27708008
RRP41_YEAST	SKI6	genetic	27708008
RRP3_YEAST	RRP3	genetic	27708008
UTP9_YEAST	UTP9	genetic	27708008
MTR4_YEAST	MTR4	genetic	27708008
NUP85_YEAST	NUP85	genetic	27708008
PRI2_YEAST	PRI2	genetic	27708008
MIF2_YEAST	MIF2	genetic	27708008
ABF1_YEAST	ABF1	genetic	27708008
DCA13_YEAST	SOF1	genetic	27708008
COFI_YEAST	COF1	genetic	27708008
SEN1_YEAST	SEN1	genetic	27708008
CDC91_YEAST	GAB1	genetic	27708008
MCM1_YEAST	MCM1	genetic	27708008
RRP5_YEAST	RRP5	genetic	27708008
HAS1_YEAST	HAS1	genetic	27708008
DPOA_YEAST	POL1	genetic	27708008
NAT10_YEAST	KRE33	genetic	27708008
RRP44_YEAST	DIS3	genetic	27708008
NUF2_YEAST	NUF2	genetic	27708008
SMP3_YEAST	SMP3	genetic	27708008
GRPE_YEAST	MGE1	genetic	27708008
IPL1_YEAST	IPL1	genetic	27708008
NSL1_YEAST	NSL1	genetic	27708008
DIM1_YEAST	DIM1	genetic	27708008
SEC23_YEAST	SEC23	genetic	27708008
ATS1_YEAST	ATS1	genetic	27708008
NUP60_YEAST	NUP60	genetic	27708008
CSG2_YEAST	CSG2	genetic	27708008
TPS1_YEAST	TPS1	genetic	27708008
SWC5_YEAST	SWC5	genetic	27708008
BIK1_YEAST	BIK1	genetic	27708008
GPR1_YEAST	GPR1	genetic	27708008
YD180_YEAST	YDL180W	genetic	27708008
NOP6_YEAST	NOP6	genetic	27708008
RRP8_YEAST	RRP8	genetic	27708008
SAC3_YEAST	SAC3	genetic	27708008
MNN10_YEAST	MNN10	genetic	27708008
IPK1_YEAST	IPK1	genetic	27708008
YG1I_YEAST	YGR026W	genetic	27708008
SLX9_YEAST	SLX9	genetic	27708008
LRP1_YEAST	LRP1	genetic	27708008
YIA6_YEAST	YIA6	genetic	27708008
PBS2_YEAST	PBS2	genetic	27708008
MNS1_YEAST	MNS1	genetic	27708008
RL14A_YEAST	RPL14A	genetic	27708008
PAN3_YEAST	PAN3	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
HBS1_YEAST	HBS1	genetic	27708008
ENV10_YEAST	ENV10	genetic	27708008
SIC1_YEAST	SIC1	genetic	27708008
VIP1_YEAST	VIP1	genetic	27708008
RS3A1_YEAST	RPS1A	genetic	27708008
PSP2_YEAST	PSP2	genetic	27708008
SCS7_YEAST	SCS7	genetic	27708008
BUL1_YEAST	BUL1	genetic	27708008
DOM34_YEAST	DOM34	genetic	27708008
MAS5_YEAST	YDJ1	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
RAS2_YEAST	RAS2	genetic	27708008
YNO0_YEAST	YNL140C	genetic	27708008
RRP6_YEAST	RRP6	genetic	27708008
STI1_YEAST	STI1	genetic	27708008
BUD21_YEAST	BUD21	genetic	27708008
MBF1_YEAST	MBF1	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008
HSP7F_YEAST	SSE1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UTP13_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-359, AND MASSSPECTROMETRY.	18407956 [Abstract]