DIM1_YEAST - dbPTM
DIM1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DIM1_YEAST
UniProt AC P41819
Protein Name Dimethyladenosine transferase
Gene Name DIM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 318
Subcellular Localization Cytoplasm . Nucleus, nucleolus .
Protein Description Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle..
Protein Sequence MGKAAKKKYSGATSSKQVSAEKHLSSVFKFNTDLGQHILKNPLVAQGIVDKAQIRPSDVVLEVGPGTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFALRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNNFRPPPQVESSVVRLEIKNPRPQVDYNEWDGLLRIVFVRKNRTISAGFKSTTVMDILEKNYKTFLAMNNEMVDDTKGSMHDVVKEKIDTVLKETDLGDKRAGKCDQNDFLRLLYAFHQVGIHFS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Acetylation-MGKAAKKKYSGATS
-CCHHCCCCCCCCCC		52.8225381059
8AcetylationMGKAAKKKYSGATSS
CCHHCCCCCCCCCCC		43.9025381059
16AcetylationYSGATSSKQVSAEKH
CCCCCCCCCCCHHHH		55.2622865919
22AcetylationSKQVSAEKHLSSVFK
CCCCCHHHHHHHHHH		49.9524489116
25PhosphorylationVSAEKHLSSVFKFNT
CCHHHHHHHHHHCCC		24.9521440633
29AcetylationKHLSSVFKFNTDLGQ
HHHHHHHHCCCCHHH		35.2325381059
40AcetylationDLGQHILKNPLVAQG
CHHHHHHCCHHHHCC		56.7822865919
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DIM1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DIM1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DIM1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RRP12_YEASTRRP12physical
16429126
EF3A_YEASTYEF3physical
16429126
TSR1_YEASTTSR1physical
16429126
PNO1_YEASTPNO1physical
15037774
SLA2_YEASTSLA2physical
18719252
RIM1_YEASTRIM1genetic
20093466
ELO2_YEASTELO2genetic
20093466
YCY0_YEASTYCR090Cgenetic
20093466
RL41A_YEASTRPL41Agenetic
20093466
RL41B_YEASTRPL41Agenetic
20093466
YD180_YEASTYDL180Wgenetic
20093466
MED5_YEASTNUT1genetic
20093466
SLX9_YEASTSLX9genetic
20093466
IML2_YEASTIML2genetic
20093466
SAC1_YEASTSAC1genetic
20093466
SIC1_YEASTSIC1genetic
20093466
NST1_YEASTNST1genetic
20093466
VPS21_YEASTVPS21genetic
20093466
MED1_YEASTMED1genetic
20093466
ATG13_YEASTATG13genetic
20093466
RIO2_YEASTRIO2physical
21283762
LTV1_YEASTLTV1physical
21283762
TCPD_YEASTCCT4genetic
27708008
NEP1_YEASTEMG1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
DYR_YEASTDFR1genetic
27708008
CHK1_YEASTCHK1genetic
27708008
PMP3_YEASTPMP3genetic
27708008
EIF3J_YEASTHCR1genetic
27708008
NAM7_YEASTNAM7genetic
27708008
MCES_YEASTABD1genetic
27708008
RRP42_YEASTRRP42genetic
27708008
NOP14_YEASTNOP14genetic
27708008
GLE1_YEASTGLE1genetic
27708008
CDC37_YEASTCDC37genetic
27708008
CDC1_YEASTCDC1genetic
27708008
RRP45_YEASTRRP45genetic
27708008
GPI8_YEASTGPI8genetic
27708008
UTP5_YEASTUTP5genetic
27708008
UTP6_YEASTUTP6genetic
27708008
RSP5_YEASTRSP5genetic
27708008
NUP57_YEASTNUP57genetic
27708008
RRP41_YEASTSKI6genetic
27708008
KRE9_YEASTKRE9genetic
27708008
NUP85_YEASTNUP85genetic
27708008
CDC11_YEASTCDC11genetic
27708008
NOP56_YEASTNOP56genetic
27708008
UTP13_YEASTUTP13genetic
27708008
GSP1_YEASTGSP1genetic
27708008
NAT10_YEASTKRE33genetic
27708008
HIR1_YEASTHIR1genetic
27708008
NU170_YEASTNUP170genetic
27708008
H4_YEASTHHF1genetic
27708008
PP2C4_YEASTPTC4genetic
27708008
PYC2_YEASTPYC2genetic
27708008
YCZ2_YEASTYCR102Cgenetic
27708008
VAM6_YEASTVAM6genetic
27708008
PST1_YEASTPST1genetic
27708008
HIM1_YEASTHIM1genetic
27708008
DYL1_YEASTDYN2genetic
27708008
FDC1_YEASTFDC1genetic
27708008
ACA1_YEASTACA1genetic
27708008
MIC19_YEASTMIC19genetic
27708008
LRP1_YEASTLRP1genetic
27708008
THP2_YEASTTHP2genetic
27708008
MND2_YEASTMND2genetic
27708008
MNN11_YEASTMNN11genetic
27708008
YJ31_YEASTYJR061Wgenetic
27708008
FABG_YEASTOAR1genetic
27708008
FRMSR_YEASTYKL069Wgenetic
27708008
MCR1_YEASTMCR1genetic
27708008
DBP7_YEASTDBP7genetic
27708008
HBS1_YEASTHBS1genetic
27708008
SRL3_YEASTSRL3genetic
27708008
SIC1_YEASTSIC1genetic
27708008
AMPD_YEASTAMD1genetic
27708008
IMDH4_YEASTIMD4genetic
27708008
ASND1_YEASTYML096Wgenetic
27708008
HOT1_YEASTHOT1genetic
27708008
DOM34_YEASTDOM34genetic
27708008
SIW14_YEASTSIW14genetic
27708008
YNF0_YEASTYNL050Cgenetic
27708008
MAS5_YEASTYDJ1genetic
27708008
RRP6_YEASTRRP6genetic
27708008
RRP12_YEASTRRP12physical
25474739
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DIM1_YEAST

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Related Literatures of Post-Translational Modification

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