| UniProt ID | MCES_YEAST | |
|---|---|---|
| UniProt AC | P32783 | |
| Protein Name | mRNA cap guanine-N7 methyltransferase | |
| Gene Name | ABD1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 436 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Responsible for methylating the 5'-cap structure of mRNAs.. | |
| Protein Sequence | MSTKPEKPIWMSQEDYDRQYGSITGDESSTVSKKDSKVTANAPGDGNGSLPVLQSSSILTSKVSDLPIEAESGFKIQKRRHERYDQEERLRKQRAQKLREEQLKRHEIEMTANRSINVDQIVREHYNERTIIANRAKRNLSPIIKLRNFNNAIKYMLIDKYTKPGDVVLELGCGKGGDLRKYGAAGISQFIGIDISNASIQEAHKRYRSMRNLDYQVVLITGDCFGESLGVAVEPFPDCRFPCDIVSTQFCLHYAFETEEKARRALLNVAKSLKIGGHFFGTIPDSEFIRYKLNKFPKEVEKPSWGNSIYKVTFENNSYQKNDYEFTSPYGQMYTYWLEDAIDNVPEYVVPFETLRSLADEYGLELVSQMPFNKFFVQEIPKWIERFSPKMREGLQRSDGRYGVEGDEKEAASYFYTMFAFRKVKQYIEPESVKPN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 12 | Phosphorylation | PEKPIWMSQEDYDRQ CCCCCCCCHHHHHCC | 18.54 | 20190278 | |
| 64 | Phosphorylation | SILTSKVSDLPIEAE CCCCCCCCCCCCCCC | 36.85 | 30377154 | |
| 75 | Acetylation | IEAESGFKIQKRRHE CCCCCCCCCCHHHHH | 47.99 | 24489116 | |
| 115 | Phosphorylation | IEMTANRSINVDQIV CCHHHCCCCCHHHHH | 20.51 | 28889911 | |
| 141 | Phosphorylation | NRAKRNLSPIIKLRN CHHHCCCCHHEEECC | 20.01 | 21440633 | |
| 161 | Phosphorylation | KYMLIDKYTKPGDVV HHHHHCCCCCCCCEE | 19.09 | 29688323 | |
| 162 | Phosphorylation | YMLIDKYTKPGDVVL HHHHCCCCCCCCEEE | 36.18 | 29688323 | |
| 388 | Phosphorylation | PKWIERFSPKMREGL HHHHHHHCHHHHHHH | 29.81 | 21440633 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MCES_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MCES_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MCES_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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