PLB2_YEAST - dbPTM
PLB2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PLB2_YEAST
UniProt AC Q03674
Protein Name Lysophospholipase 2
Gene Name PLB2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 706
Subcellular Localization Secreted, cell wall. Membrane
Lipid-anchor, GPI-anchor. Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Protein Description Sequentially removes both fatty acyl groups from diacylglycerophospholipids and therefore has both phospholipase A and lysophospholipase activities. Substrate preference is phosphatidylserine > phosphatidylinositol > phosphatidylcholine > phosphatidylethanolamine..
Protein Sequence MQLRNILQASSLISGLSLAADSSSTTGDGYAPSIIPCPSDDTSLVRNASGLSTAETDWLKKRDAYTKEALHSFLSRATSNFSDTSLLSTLFSSNSSNVPKIGIACSGGGYRAMLGGAGMIAAMDNRTDGANEHGLGGLLQSSTYLSGLSGGNWLTGTLAWNNWTSVQEIVDHMSESDSIWNITKSIVNPGGSNLTYTIERWESIVQEVQAKSDAGFNISLSDLWARALSYNFFPSLPDAGSALTWSSLRDVDVFKNGEMPLPITVADGRYPGTTVINLNATLFEFTPFEMGSWDPSLNAFTDVKYLGTNVTNGKPVNKDQCVSGYDNAGFVIATSASLFNEFSLEASTSTYYKMINSFANKYVNNLSQDDDDIAIYAANPFKDTEFVDRNYTSSIVDADDLFLVDGGEDGQNLPLVPLIKKERDLDVVFALDISDNTDESWPSGVCMTNTYERQYSKQGKGMAFPYVPDVNTFLNLGLTNKPTFFGCDAKNLTDLEYIPPLVVYIPNTKHSFNGNQSTLKMNYNVTERLGMIRNGFEAATMGNFTDDSNFLGCIGCAIIRRKQESLNATLPPECTKCFADYCWNGTLSTSANPELSGNSTYQSGAIASAISEATDGIPITALLGSSTSGNTTSNSTTSTSSNVTSNSNSSSNTTLNSNSSSSSISSSTARSSSSTANKANAAAISYANTNTLMSLLGAITALFGLI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
47N-linked_GlycosylationDDTSLVRNASGLSTA
CCCHHHCCCCCCCHH		30.86-
80N-linked_GlycosylationFLSRATSNFSDTSLL
HHHHHHCCCCCHHHH		35.77-
94N-linked_GlycosylationLSTLFSSNSSNVPKI
HHHHHCCCCCCCCEE		48.54-
125N-linked_GlycosylationGMIAAMDNRTDGANE
HHEEEECCCCCCCCC		35.35-
162N-linked_GlycosylationTGTLAWNNWTSVQEI
CCEEECCCCCCHHHH		32.47-
181N-linked_GlycosylationSESDSIWNITKSIVN
CCCHHHHEEEEHHCC		30.31-
193N-linked_GlycosylationIVNPGGSNLTYTIER
HCCCCCCCCEEEHHH		39.41-
217N-linked_GlycosylationAKSDAGFNISLSDLW
HHCCCCCCCCHHHHH		23.25-
255AcetylationLRDVDVFKNGEMPLP
CCCCCCCCCCCCCCC		64.9824489116
279N-linked_GlycosylationGTTVINLNATLFEFT
CCEEEECCCEEEEEC		26.79-
309N-linked_GlycosylationDVKYLGTNVTNGKPV
CCEECCEECCCCCCC		36.50-
365N-linked_GlycosylationFANKYVNNLSQDDDD
HHHHHHHCCCCCCCC		30.90-
390N-linked_GlycosylationDTEFVDRNYTSSIVD
CCCCCCCCCCCCEEC		39.71-
491N-linked_GlycosylationFFGCDAKNLTDLEYI
CCCCCCCCCCCCCCC		50.31-
515N-linked_GlycosylationTKHSFNGNQSTLKMN
CCCCCCCCCCEEEEE		33.46-
524N-linked_GlycosylationSTLKMNYNVTERLGM
CEEEEECCHHHHHCC		29.27-
540PhosphorylationRNGFEAATMGNFTDD
CCCCCCCCCCCCCCC		32.4327017623
543N-linked_GlycosylationFEAATMGNFTDDSNF
CCCCCCCCCCCCCCC		26.31-
545PhosphorylationAATMGNFTDDSNFLG
CCCCCCCCCCCCCHH		42.7827017623
548PhosphorylationMGNFTDDSNFLGCIG
CCCCCCCCCCHHHHH		32.0927017623
567N-linked_GlycosylationRRKQESLNATLPPEC
HCCHHHHCCCCCHHH		39.91-
584N-linked_GlycosylationCFADYCWNGTLSTSA
HHCHHCCCCEECCCC		29.97-
598N-linked_GlycosylationANPELSGNSTYQSGA
CCCCCCCCCCCCCCH		28.01-
630N-linked_GlycosylationLGSSTSGNTTSNSTT
EECCCCCCCCCCCEE		39.69-
634N-linked_GlycosylationTSGNTTSNSTTSTSS
CCCCCCCCCEECCCC		41.08-
642N-linked_GlycosylationSTTSTSSNVTSNSNS
CEECCCCCCCCCCCC		40.63-
648N-linked_GlycosylationSNVTSNSNSSSNTTL
CCCCCCCCCCCCCEE		50.60-
652N-linked_GlycosylationSNSNSSSNTTLNSNS
CCCCCCCCCEECCCC		38.74-
658N-linked_GlycosylationSNTTLNSNSSSSSIS
CCCEECCCCCCCCCC		44.85-
680GPI-anchorSSTANKANAAAISYA
CCCCCHHHHHHHHHH		31.55-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PLB2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PLB2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PLB2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DUN1_YEASTDUN1genetic
19269370
PSR1_YEASTPSR1genetic
19269370
WHI5_YEASTWHI5genetic
19269370
PGLR_YEASTPGU1genetic
21623372
SKN1_YEASTSKN1genetic
21623372
DUR3_YEASTDUR3genetic
21623372
KTR6_YEASTKTR6genetic
21623372
ADE_YEASTAAH1genetic
21623372
IAH1_YEASTIAH1genetic
21623372
INO1_YEASTINO1genetic
21623372
TRXB2_YEASTTRR2genetic
21623372
AYR1_YEASTAYR1genetic
21623372
AHP1_YEASTAHP1genetic
21623372
ADK_YEASTADO1genetic
21623372
PUT4_YEASTPUT4genetic
21623372
SERC_YEASTSER1genetic
21623372
YEH1_YEASTYEH1genetic
21623372
ASNS2_YEASTASN2genetic
21623372
IDH2_YEASTIDH2genetic
21623372
MAL11_YEASTMAL11genetic
21623372
THIK_YEASTPOT1genetic
21623372
TREB_YEASTNTH2genetic
21623372
GPDM_YEASTGUT2genetic
21623372
GLRX2_YEASTGRX2genetic
21623372
MDHC_YEASTMDH2genetic
21623372
EPT1_YEASTEPT1genetic
21623372
GYS1_YEASTGSY1genetic
21623372
ARA1_YEASTARA1genetic
21623372
LAC1_YEASTLAC1genetic
21623372
TRPG_YEASTTRP3genetic
21623372
PYR1_YEASTURA2genetic
21623372
COX6_YEASTCOX6genetic
21623372
CY1_YEASTCYT1genetic
21623372
KTR5_YEASTKTR5genetic
21623372
RFT1_YEASTRFT1genetic
23891562
MON2_YEASTMON2genetic
23891562
PP2C3_YEASTPTC3genetic
27708008
ETR1_YEASTETR1genetic
27708008
IML3_YEASTIML3genetic
27708008
GPI11_YEASTGPI11genetic
27708008
GPI19_YEASTGPI19genetic
27708008
GNA1_YEASTGNA1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
RNA1_YEASTRNA1genetic
27708008
HSP71_YEASTSSA1genetic
27708008
SNC1_YEASTSNC1genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
AP2A_YEASTAPL3genetic
27708008
HSP73_YEASTSSA3genetic
27708008
RCR1_YEASTRCR1genetic
27708008
FAT1_YEASTFAT1genetic
27708008
YBQ6_YEASTYBR056Wgenetic
27708008
ECM8_YEASTECM8genetic
27708008
ICS2_YEASTICS2genetic
27708008
SHG1_YEASTSHG1genetic
27708008
URH1_YEASTURH1genetic
27708008
TFS2_YEASTDST1genetic
27708008
PDK1_YEASTPKP1genetic
27708008
YJY1_YEASTYJR011Cgenetic
27708008
EAF6_YEASTEAF6genetic
27708008
SAC1_YEASTSAC1genetic
27708008
TDA1_YEASTTDA1genetic
27708008
PET8_YEASTPET8genetic
27708008
CEX1_YEASTCEX1genetic
27708008
MPC54_YEASTMPC54genetic
27708008
KES1_YEASTKES1genetic
27708008
CISY3_YEASTCIT3genetic
27708008
CTF4_YEASTCTF4genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PLB2_YEAST

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Related Literatures of Post-Translational Modification

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