TRXB2_YEAST - dbPTM
TRXB2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TRXB2_YEAST
UniProt AC P38816
Protein Name Thioredoxin reductase 2, mitochondrial
Gene Name TRR2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 342
Subcellular Localization Mitochondrion .
Protein Description Acts on mitochondrial thioredoxin 3. Implicated in the defense against oxidative stress..
Protein Sequence MIKHIVSPFRTNFVGISKSVLSRMIHHKVTIIGSGPAAHTAAIYLARAEMKPTLYEGMMANGIAAGGQLTTTTDIENFPGFPESLSGSELMERMRKQSAKFGTNIITETVSKVDLSSKPFRLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQQGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAEFLTKYASKVYILVRKDHFRASVIMQRRIEKNPNIIVLFNTVALEAKGDGKLLNMLRIKNTKSNVENDLEVNGLFYAIGHSPATDIVKGQVDEEETGYIKTVPGSSLTSVPGFFAAGDVQDSRYRQAVTSAGSGCIAALDAERYLSAQE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
30PhosphorylationRMIHHKVTIIGSGPA
HHHCCCEEEECCCHH		16.2222369663
34PhosphorylationHKVTIIGSGPAAHTA
CCEEEECCCHHHHHH		31.0623749301
40PhosphorylationGSGPAAHTAAIYLAR
CCCHHHHHHHHHHHH		17.0422369663
44PhosphorylationAAHTAAIYLARAEMK
HHHHHHHHHHHHHCC		6.9222369663
111PhosphorylationNIITETVSKVDLSSK
CCCCEECCCCCCCCC		34.0925315811
302PhosphorylationVPGSSLTSVPGFFAA
CCCCCCCCCCCEEEC		31.4428889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TRXB2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TRXB2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TRXB2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TRXB1_YEASTTRR1physical
18719252
TRX3_YEASTTRX3physical
18930846
TRXB1_YEASTTRR1genetic
18408719
TRX3_YEASTTRX3genetic
15701801
ERG2_YEASTERG2genetic
21623372
GSHR_YEASTGLR1genetic
22770501
TRX3_YEASTTRX3genetic
22770501
MCA1_YEASTMCA1genetic
22770501
PRX1_YEASTPRX1genetic
22770501
TRXB2_YEASTTRR2physical
22940862
TRXB1_YEASTTRR1physical
22940862
CSN12_YEASTYJR084Wgenetic
27708008
SIC1_YEASTSIC1genetic
27708008
SCS7_YEASTSCS7genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TRXB2_YEAST

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Related Literatures of Post-Translational Modification

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