MAL11_YEAST - dbPTM
MAL11_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MAL11_YEAST
UniProt AC P53048
Protein Name General alpha-glucoside permease
Gene Name MAL11
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 616
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description High-affinity uptake of alpha-glucosides such as maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose, melezitose and glucose. Acts with the concomitant transport of protons into the cell (symport system)..
Protein Sequence MKNIISLVSKKKAASKNEDKNISESSRDIVNQQEVFNTEDFEEGKKDSAFELDHLEFTTNSAQLGDSDEDNENVINEMNATDDANEANSEEKSMTLKQALLKYPKAALWSILVSTTLVMEGYDTALLSALYALPVFQRKFGTLNGEGSYEITSQWQIGLNMCVLCGEMIGLQITTYMVEFMGNRYTMITALGLLTAYIFILYYCKSLAMIAVGQILSAIPWGCFQSLAVTYASEVCPLALRYYMTSYSNICWLFGQIFASGIMKNSQENLGNSDLGYKLPFALQWIWPAPLMIGIFFAPESPWWLVRKDRVAEARKSLSRILSGKGAEKDIQVDLTLKQIELTIEKERLLASKSGSFFNCFKGVNGRRTRLACLTWVAQNSSGAVLLGYSTYFFERAGMATDKAFTFSLIQYCLGLAGTLCSWVISGRVGRWTILTYGLAFQMVCLFIIGGMGFGSGSSASNGAGGLLLALSFFYNAGIGAVVYCIVAEIPSAELRTKTIVLARICYNLMAVINAILTPYMLNVSDWNWGAKTGLYWGGFTAVTLAWVIIDLPETTGRTFSEINELFNQGVPARKFASTVVDPFGKGKTQHDSLADESISQSSSIKQRELNAADKC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
185PhosphorylationVEFMGNRYTMITALG
HHHCCCHHHHHHHHH		12.5028889911
186PhosphorylationEFMGNRYTMITALGL
HHCCCHHHHHHHHHH		10.0028889911
189PhosphorylationGNRYTMITALGLLTA
CCHHHHHHHHHHHHH		12.6627017623
195PhosphorylationITALGLLTAYIFILY
HHHHHHHHHHHHHHH		23.5827017623
197PhosphorylationALGLLTAYIFILYYC
HHHHHHHHHHHHHHH		7.3628889911
202PhosphorylationTAYIFILYYCKSLAM
HHHHHHHHHHHHHHH		11.2928889911
203PhosphorylationAYIFILYYCKSLAMI
HHHHHHHHHHHHHHH		7.0328889911
523N-linked_GlycosylationILTPYMLNVSDWNWG
HHCHHHCCCHHCCCC		18.08-
589PhosphorylationDPFGKGKTQHDSLAD
CCCCCCCCCCHHHCC		39.5429136822
598PhosphorylationHDSLADESISQSSSI
CHHHCCHHHHCCHHH		28.2529136822
600PhosphorylationSLADESISQSSSIKQ
HHCCHHHHCCHHHHH		33.0329136822
602PhosphorylationADESISQSSSIKQRE
CCHHHHCCHHHHHHH		21.1829136822
603PhosphorylationDESISQSSSIKQREL
CHHHHCCHHHHHHHH		28.5729136822
604PhosphorylationESISQSSSIKQRELN
HHHHCCHHHHHHHHH		38.7729136822
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MAL11_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MAL11_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CSG2_YEASTCSG2genetic
20093466
TCM62_YEASTTCM62genetic
20093466
YBQ6_YEASTYBR056Wgenetic
20093466
HPC2_YEASTHPC2genetic
20093466
SGF29_YEASTSGF29genetic
20093466
RV161_YEASTRVS161genetic
20093466
YD157_YEASTYDL157Cgenetic
20093466
VPS41_YEASTVPS41genetic
20093466
RS17B_YEASTRPS17Bgenetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
MMS2_YEASTMMS2genetic
20093466
PALF_YEASTRIM8genetic
20093466
PCP1_YEASTPCP1genetic
20093466
MIP6_YEASTMIP6genetic
20093466
COX23_YEASTCOX23genetic
20093466
PTH_YEASTPTH1genetic
20093466
PTPA1_YEASTRRD1genetic
20093466
VHR1_YEASTVHR1genetic
20093466
CBT1_YEASTCBT1genetic
20093466
RGT1_YEASTRGT1genetic
20093466
POM33_YEASTPOM33genetic
20093466
MMM1_YEASTMMM1genetic
20093466
ELP1_YEASTIKI3genetic
20093466
VPS9_YEASTVPS9genetic
20093466
PEX12_YEASTPEX12genetic
20093466
RIM13_YEASTRIM13genetic
20093466
PFKA2_YEASTPFK2genetic
20093466
COX7_YEASTCOX7genetic
20093466
AEP2_YEASTAEP2genetic
20093466
LSM7_YEASTLSM7genetic
20093466
FAR11_YEASTFAR11genetic
20093466
SHE4_YEASTSHE4genetic
20093466
GLO4_YEASTGLO4genetic
20093466
WHI2_YEASTWHI2genetic
20093466
SUE1_YEASTSUE1genetic
20093466
PHO88_YEASTPHO88physical
16093310
FUS1_YEASTFUS1physical
16093310
ELO2_YEASTELO2physical
16093310
ERG1_YEASTERG1physical
16093310
ERV29_YEASTERV29physical
16093310
SNL1_YEASTSNL1physical
16093310
SRPB_YEASTSRP102physical
16093310
ELO3_YEASTELO3physical
16093310
PFA4_YEASTPFA4physical
16093310
YOP1_YEASTYOP1physical
16093310
MAL12_YEASTMAL12genetic
20471265
MAL32_YEASTMAL32genetic
20471265
IMA2_YEASTIMA2genetic
20471265
MALX3_YEASTIMA1genetic
20471265
YEH2_YEASTYEH2genetic
21623372
PHO84_YEASTPHO84genetic
21623372
DHAS_YEASTHOM2genetic
21623372
RS25A_YEASTRPS25Aphysical
22940862
COQ7_YEASTCAT5genetic
27708008
NU170_YEASTNUP170genetic
27708008
CSG2_YEASTCSG2genetic
27708008
TCM62_YEASTTCM62genetic
27708008
YBQ6_YEASTYBR056Wgenetic
27708008
MBA1_YEASTMBA1genetic
27708008
HPC2_YEASTHPC2genetic
27708008
YB91_YEASTYBR241Cgenetic
27708008
REI1_YEASTREI1genetic
27708008
SGF29_YEASTSGF29genetic
27708008
RV161_YEASTRVS161genetic
27708008
RIM1_YEASTRIM1genetic
27708008
IMG2_YEASTIMG2genetic
27708008
MTU1_YEASTSLM3genetic
27708008
YD157_YEASTYDL157Cgenetic
27708008
RL35A_YEASTRPL35Agenetic
27708008
RL35B_YEASTRPL35Agenetic
27708008
PMP3_YEASTPMP3genetic
27708008
RS17B_YEASTRPS17Bgenetic
27708008
PT122_YEASTPET122genetic
27708008
SA155_YEASTSAP155genetic
27708008
YGY5_YEASTYGL235Wgenetic
27708008
DBF2_YEASTDBF2genetic
27708008
NPR3_YEASTNPR3genetic
27708008
NEM1_YEASTNEM1genetic
27708008
COX23_YEASTCOX23genetic
27708008
PTH_YEASTPTH1genetic
27708008
GSH1_YEASTGSH1genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
RS27A_YEASTRPS27Agenetic
27708008
KAPC_YEASTTPK3genetic
27708008
CBT1_YEASTCBT1genetic
27708008
MMM1_YEASTMMM1genetic
27708008
POM33_YEASTPOM33genetic
27708008
COX12_YEASTCOX12genetic
27708008
COA4_YEASTCOA4genetic
27708008
RS29A_YEASTRPS29Agenetic
27708008
VPS9_YEASTVPS9genetic
27708008
COX7_YEASTCOX7genetic
27708008
AEP2_YEASTAEP2genetic
27708008
FAR11_YEASTFAR11genetic
27708008
LSM7_YEASTLSM7genetic
27708008
IRA2_YEASTIRA2genetic
27708008
GLO4_YEASTGLO4genetic
27708008
CY1_YEASTCYT1genetic
27708008
QCR2_YEASTQCR2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MAL11_YEAST

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Related Literatures of Post-Translational Modification

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