IMA2_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IMA2_YEAST
• UniProt AC: Q08295
• Protein Name: Oligo-1,6-glucosidase IMA2
• Gene Name: IMA2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 589
• Protein Description: Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose..
• Protein Sequence: MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQPSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMQHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
282	Phosphorylation	VGEMQHATDETKRLY HHHEECCCHHHHHHH	32.04	27017623
285	Phosphorylation	MQHATDETKRLYTSA EECCCHHHHHHHHHC	25.03	27017623
366	Ubiquitination	RFGDDSPKNRVISGK ECCCCCCCCCCCCHH	62.43	23749301
447	Phosphorylation	ISRDHARTPMQWSRE HCCCCCCCCCCCCCC	24.72	29136822

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IMA2_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IMA2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IMA2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MET30_YEAST	MET30	genetic	27708008
MCM1_YEAST	MCM1	genetic	27708008
DED1_YEAST	DED1	genetic	27708008
NIP7_YEAST	NIP7	genetic	27708008
RL22A_YEAST	RPL22A	genetic	27708008
RU2A_YEAST	LEA1	genetic	27708008
CALM_YEAST	CMD1	genetic	27708008
MAK5_YEAST	MAK5	genetic	27708008
PRP5_YEAST	PRP5	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
DPOD_YEAST	POL3	genetic	27708008
NSE4_YEAST	NSE4	genetic	27708008
CDC48_YEAST	CDC48	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
COG3_YEAST	COG3	genetic	27708008
COPB2_YEAST	SEC27	genetic	27708008
MED6_YEAST	MED6	genetic	27708008
CDC6_YEAST	CDC6	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
YJ9I_YEAST	YJR141W	genetic	27708008
NSE1_YEAST	NSE1	genetic	27708008
MED14_YEAST	RGR1	genetic	27708008
NMT_YEAST	NMT1	genetic	27708008
SEC39_YEAST	SEC39	genetic	27708008
ARP9_YEAST	ARP9	genetic	27708008
GPI12_YEAST	GPI12	genetic	27708008
CAP_YEAST	SRV2	genetic	27708008
NOG2_YEAST	NOG2	genetic	27708008
MED4_YEAST	MED4	genetic	27708008
APC5_YEAST	APC5	genetic	27708008
GPN2_YEAST	GPN2	genetic	27708008
SYA_YEAST	ALA1	genetic	27708008
SEC62_YEAST	SEC62	genetic	27708008
SWC3_YEAST	SWC3	genetic	27708008
ATC3_YEAST	DRS2	genetic	27708008
SHE1_YEAST	SHE1	genetic	27708008
RMD9L_YEAST	YBR238C	genetic	27708008
BUD31_YEAST	BUD31	genetic	27708008
RLA1_YEAST	RPP1A	genetic	27708008
GCS1_YEAST	GCS1	genetic	27708008
UME6_YEAST	UME6	genetic	27708008
MRM2_YEAST	MRM2	genetic	27708008
CHO2_YEAST	CHO2	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
CSF1_YEAST	CSF1	genetic	27708008
ALAM_YEAST	ALT1	genetic	27708008
ELO3_YEAST	ELO3	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
TGS1_YEAST	TGS1	genetic	27708008
RTC6_YEAST	RTC6	genetic	27708008
YME1_YEAST	YME1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.