| UniProt ID | SRPB_YEAST | |
|---|---|---|
| UniProt AC | P36057 | |
| Protein Name | Signal recognition particle receptor subunit beta | |
| Gene Name | SRP102 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 244 | |
| Subcellular Localization | Endoplasmic reticulum membrane . | |
| Protein Description | Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.. | |
| Protein Sequence | MLSNTLIIACLLVIGTTIALIAVQKASSKTGIKQKSYQPSIIIAGPQNSGKTSLLTLLTTDSVRPTVVSQEPLSAADYDGSGVTLVDFPGHVKLRYKLSDYLKTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFTARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLEASVVAFEGSINKRKISQWREWIDEKL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MLSNTLIIAC -----CCCHHHHHHH | 26.86 | 25521595 | |
| 17 | Phosphorylation | CLLVIGTTIALIAVQ HHHHHHHHHHHHHHH | 10.07 | 25521595 | |
| 27 | Phosphorylation | LIAVQKASSKTGIKQ HHHHHHHHCCCCCCC | 39.13 | 25521595 | |
| 97 | Acetylation | GHVKLRYKLSDYLKT CCEEEEEEHHHHHHH | 34.77 | 24489116 | |
| 177 | Acetylation | ALESEIQKVIERRKK HHHHHHHHHHHHHHH | 51.33 | 24489116 | |
| 192 | Ubiquitination | SLNEVERKINEEDYA HHHHHHHHHCHHHHH | 36.06 | 23749301 | |
| 208 | Phosphorylation | NTLDVLQSTDGFKFA HHHHHHHCCCCCCCC | 25.06 | 19779198 | |
| 209 | Phosphorylation | TLDVLQSTDGFKFAN HHHHHHCCCCCCCCC | 27.47 | 19779198 | |
| 220 | Phosphorylation | KFANLEASVVAFEGS CCCCEEEEEEEEECC | 14.03 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SRPB_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SRPB_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SRPB_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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