| UniProt ID | NMD4_YEAST | |
|---|---|---|
| UniProt AC | Q12129 | |
| Protein Name | Nonsense-mediated decay protein 4 | |
| Gene Name | NMD4 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 218 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Involved in nonsense-mediated decay of mRNAs containing premature stop codons.. | |
| Protein Sequence | MTQYNFIIDASAFEKGLGNIKRWCSDCTEAVTLNFYIPTFTLNELDFLQQRRKSFAARESLKFIDRLDDSKFANLKVFIEFPEVLDIILWSDVMEHNDSSGKINIAKLPKRLKNLLKSCIYKCYLEGNEGLHWFLISEDPQIREMAMQCNIPSCSIVDVDSILSKDMNDKSFRESEKFNNMMLKNGTKEESENGREIIRTNFNKTVYASRGTGELWSP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MTQYNFIIDAS ----CCCCCEEEEHH | 11.68 | 28132839 | |
| 204 | Acetylation | IIRTNFNKTVYASRG EEECCCCCEEEECCC | 34.92 | 25381059 | |
| 217 | Phosphorylation | RGTGELWSP------ CCCCCCCCC------ | 33.10 | 25521595 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NMD4_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NMD4_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NMD4_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TCPZ_YEAST | CCT6 | genetic | 27708008 | |
| STU1_YEAST | STU1 | genetic | 27708008 | |
| PRP6_YEAST | PRP6 | genetic | 27708008 | |
| APC11_YEAST | APC11 | genetic | 27708008 | |
| CDC37_YEAST | CDC37 | genetic | 27708008 | |
| GPI11_YEAST | GPI11 | genetic | 27708008 | |
| RMRP_YEAST | SNM1 | genetic | 27708008 | |
| MPPA_YEAST | MAS2 | genetic | 27708008 | |
| DNA2_YEAST | DNA2 | genetic | 27708008 | |
| KTHY_YEAST | CDC8 | genetic | 27708008 | |
| RSC9_YEAST | RSC9 | genetic | 27708008 | |
| TIM23_YEAST | TIM23 | genetic | 27708008 | |
| PROF_YEAST | PFY1 | genetic | 27708008 | |
| BUR1_YEAST | SGV1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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