NMD4_YEAST - dbPTM
NMD4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NMD4_YEAST
UniProt AC Q12129
Protein Name Nonsense-mediated decay protein 4
Gene Name NMD4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 218
Subcellular Localization Cytoplasm .
Protein Description Involved in nonsense-mediated decay of mRNAs containing premature stop codons..
Protein Sequence MTQYNFIIDASAFEKGLGNIKRWCSDCTEAVTLNFYIPTFTLNELDFLQQRRKSFAARESLKFIDRLDDSKFANLKVFIEFPEVLDIILWSDVMEHNDSSGKINIAKLPKRLKNLLKSCIYKCYLEGNEGLHWFLISEDPQIREMAMQCNIPSCSIVDVDSILSKDMNDKSFRESEKFNNMMLKNGTKEESENGREIIRTNFNKTVYASRGTGELWSP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MTQYNFIIDAS
----CCCCCEEEEHH
11.6828132839
204AcetylationIIRTNFNKTVYASRG
EEECCCCCEEEECCC
34.9225381059
217PhosphorylationRGTGELWSP------
CCCCCCCCC------
33.1025521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NMD4_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NMD4_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NMD4_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TCPZ_YEASTCCT6genetic
27708008
STU1_YEASTSTU1genetic
27708008
PRP6_YEASTPRP6genetic
27708008
APC11_YEASTAPC11genetic
27708008
CDC37_YEASTCDC37genetic
27708008
GPI11_YEASTGPI11genetic
27708008
RMRP_YEASTSNM1genetic
27708008
MPPA_YEASTMAS2genetic
27708008
DNA2_YEASTDNA2genetic
27708008
KTHY_YEASTCDC8genetic
27708008
RSC9_YEASTRSC9genetic
27708008
TIM23_YEASTTIM23genetic
27708008
PROF_YEASTPFY1genetic
27708008
BUR1_YEASTSGV1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NMD4_YEAST

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Related Literatures of Post-Translational Modification

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