LDH1_YEAST - dbPTM
LDH1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LDH1_YEAST
UniProt AC P38139
Protein Name Lipid droplet hydrolase 1
Gene Name LDH1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 375
Subcellular Localization Lipid droplet .
Protein Description Serine hydrolase required for the maintenance of steady state level of non-polar and polar lipids of lipid droplets and thus plays a role in maintaining the lipids homeostasis. Exhibits both esterase and triacylglycerol lipase activity..
Protein Sequence MNMAERAEATKSWSCEPLSGKTLEEIVQNAENAADLVAYIRKPEVDLDFRLKFIAEHEEFFNVQLSDRNSRIRTCHNLSDKGIRGDTVFVFVPGLAGNLEQFEPLLELVDSDQKAFLTLDLPGFGHSSEWSDYPMLKVVELIFVLVCDVLRKWSTAVPNNDNVNPFNGHKIVLVGHSMGCFLACHLYEQHMADTKAVQTLVLLTPPKAHIEQLSKDKHIIQWALYGVFKLPWLFDVYRNKFDQVKGLQSSGIKQYFYQQGDDVKLKYRKFWQFKNNISNKSRTIIGYLLGWETVDWVKFNGVLTQTDMKQKIIIFGAEKDPIAPIENLEFYKQTINKECLRKVIILPDCSHNLCFDRPELVCENFQREVIDNSKL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11UbiquitinationAERAEATKSWSCEPL
HHHHHHHCCCCCCCC		57.9123749301
19PhosphorylationSWSCEPLSGKTLEEI
CCCCCCCCCCCHHHH		49.2928889911
309UbiquitinationVLTQTDMKQKIIIFG
EEECCCCCCEEEEEE		51.7723749301
337UbiquitinationFYKQTINKECLRKVI
HHHHHCCHHHHCCEE		46.0523749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LDH1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LDH1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LDH1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UBX2_YEASTUBX2genetic
23891562
LCB2_YEASTLCB2genetic
23891562
ARV1_YEASTARV1genetic
23891562
ALG6_YEASTALG6genetic
23891562
ALG8_YEASTALG8genetic
23891562
STE24_YEASTSTE24genetic
23891562
AAKG_YEASTSNF4genetic
23891562
ERV14_YEASTERV14genetic
23891562
HMCS_YEASTERG13genetic
23891562
THIL_YEASTERG10genetic
23891562
DGK1_YEASTDGK1genetic
23891562
ERG7_YEASTERG7genetic
23891562
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LDH1_YEAST

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Related Literatures of Post-Translational Modification

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