PUG1_YEAST - dbPTM
PUG1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PUG1_YEAST
UniProt AC P40100
Protein Name Protoporphyrin uptake protein 1
Gene Name PUG1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 303
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Involved in inducible protoporphyrin IX influx and heme efflux..
Protein Sequence MSTTDSGFVLYHYTPSKAAAIVFVVLFIIMTVIFAVQTLYAARKSSKALKNNPFESSDDKVDSLEDAEYKQLKITPTVFAFIPFFTGCIMEAVGYIGRALSSSNPERTTPYIIQSVLLLVAPALIAATIYMIFGRLLHVMRCQSLILISARFGTTFFVVGDVFSFFLQAAGGGLMSKAGSTKTGSGLITAGLFVQVIFFGFFIINEIRFTVNVKRRCLFYEDISRKWIFVNATLLLSSMLILLRSIVRIVEFIQGFNGYIISHEYFIYVFDAVPMLLVIIAFSVGSFFGNVFDVIKECQTLSN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSTTDSGFV
------CCCCCCCEE
39.7628132839
3Phosphorylation-----MSTTDSGFVL
-----CCCCCCCEEE
33.0728132839
4Phosphorylation----MSTTDSGFVLY
----CCCCCCCEEEE
22.3628132839
6Phosphorylation--MSTTDSGFVLYHY
--CCCCCCCEEEEEC
31.8528132839
11PhosphorylationTDSGFVLYHYTPSKA
CCCCEEEEECCHHHH
6.3628132839
13PhosphorylationSGFVLYHYTPSKAAA
CCEEEEECCHHHHHH
13.5428132839
14PhosphorylationGFVLYHYTPSKAAAI
CEEEEECCHHHHHHH
14.0528132839
16PhosphorylationVLYHYTPSKAAAIVF
EEEECCHHHHHHHHH
27.4228132839
56PhosphorylationLKNNPFESSDDKVDS
HHCCCCCCCCCCCCC
39.1728889911
57PhosphorylationKNNPFESSDDKVDSL
HCCCCCCCCCCCCCH
42.5027017623
63PhosphorylationSSDDKVDSLEDAEYK
CCCCCCCCHHHHHHH
36.3227017623
154PhosphorylationLISARFGTTFFVVGD
HHHCCCCCEEEECHH
20.0929688323
155PhosphorylationISARFGTTFFVVGDV
HHCCCCCEEEECHHH
18.5629688323
164PhosphorylationFVVGDVFSFFLQAAG
EECHHHHHHHHHHCC
18.2229688323
176PhosphorylationAAGGGLMSKAGSTKT
HCCCCHHHCCCCCCC
25.1329688323

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PUG1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PUG1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PUG1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RTG2_YEASTRTG2genetic
27708008
ERV46_YEASTERV46genetic
27708008
ERP1_YEASTERP1genetic
27708008
RS8A_YEASTRPS8Agenetic
27708008
RS8B_YEASTRPS8Agenetic
27708008
AVT5_YEASTAVT5genetic
27708008
YPQ3_YEASTRTC2genetic
27708008
PANB_YEASTECM31genetic
27708008
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
PBP2_YEASTPBP2genetic
27708008
REI1_YEASTREI1genetic
27708008
DPB3_YEASTDPB3genetic
27708008
BLM10_YEASTBLM10genetic
27708008
YFF2_YEASTYFL052Wgenetic
27708008
EDC1_YEASTEDC1genetic
27708008
FZF1_YEASTFZF1genetic
27708008
YG1A_YEASTYGR016Wgenetic
27708008
RS25A_YEASTRPS25Agenetic
27708008
RL11B_YEASTRPL11Bgenetic
27708008
ASK10_YEASTASK10genetic
27708008
MEP1_YEASTMEP1genetic
27708008
TBP7_YEASTYTA7genetic
27708008
CYB5_YEASTCYB5genetic
27708008
YN8H_YEASTYNR029Cgenetic
27708008
FRE4_YEASTFRE4genetic
27708008
HST3_YEASTHST3genetic
27708008
YOR97_YEASTYOR097Cgenetic
27708008
TPO4_YEASTTPO4genetic
27708008
RNY1_YEASTRNY1genetic
27708008
NEW1_YEASTNEW1genetic
27708008
YP022_YEASTYPR022Cgenetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PUG1_YEAST

loading...

Related Literatures of Post-Translational Modification

TOP