| UniProt ID | PUG1_YEAST | |
|---|---|---|
| UniProt AC | P40100 | |
| Protein Name | Protoporphyrin uptake protein 1 | |
| Gene Name | PUG1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 303 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein . |
|
| Protein Description | Involved in inducible protoporphyrin IX influx and heme efflux.. | |
| Protein Sequence | MSTTDSGFVLYHYTPSKAAAIVFVVLFIIMTVIFAVQTLYAARKSSKALKNNPFESSDDKVDSLEDAEYKQLKITPTVFAFIPFFTGCIMEAVGYIGRALSSSNPERTTPYIIQSVLLLVAPALIAATIYMIFGRLLHVMRCQSLILISARFGTTFFVVGDVFSFFLQAAGGGLMSKAGSTKTGSGLITAGLFVQVIFFGFFIINEIRFTVNVKRRCLFYEDISRKWIFVNATLLLSSMLILLRSIVRIVEFIQGFNGYIISHEYFIYVFDAVPMLLVIIAFSVGSFFGNVFDVIKECQTLSN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSTTDSGFV ------CCCCCCCEE | 39.76 | 28132839 | |
| 3 | Phosphorylation | -----MSTTDSGFVL -----CCCCCCCEEE | 33.07 | 28132839 | |
| 4 | Phosphorylation | ----MSTTDSGFVLY ----CCCCCCCEEEE | 22.36 | 28132839 | |
| 6 | Phosphorylation | --MSTTDSGFVLYHY --CCCCCCCEEEEEC | 31.85 | 28132839 | |
| 11 | Phosphorylation | TDSGFVLYHYTPSKA CCCCEEEEECCHHHH | 6.36 | 28132839 | |
| 13 | Phosphorylation | SGFVLYHYTPSKAAA CCEEEEECCHHHHHH | 13.54 | 28132839 | |
| 14 | Phosphorylation | GFVLYHYTPSKAAAI CEEEEECCHHHHHHH | 14.05 | 28132839 | |
| 16 | Phosphorylation | VLYHYTPSKAAAIVF EEEECCHHHHHHHHH | 27.42 | 28132839 | |
| 56 | Phosphorylation | LKNNPFESSDDKVDS HHCCCCCCCCCCCCC | 39.17 | 28889911 | |
| 57 | Phosphorylation | KNNPFESSDDKVDSL HCCCCCCCCCCCCCH | 42.50 | 27017623 | |
| 63 | Phosphorylation | SSDDKVDSLEDAEYK CCCCCCCCHHHHHHH | 36.32 | 27017623 | |
| 154 | Phosphorylation | LISARFGTTFFVVGD HHHCCCCCEEEECHH | 20.09 | 29688323 | |
| 155 | Phosphorylation | ISARFGTTFFVVGDV HHCCCCCEEEECHHH | 18.56 | 29688323 | |
| 164 | Phosphorylation | FVVGDVFSFFLQAAG EECHHHHHHHHHHCC | 18.22 | 29688323 | |
| 176 | Phosphorylation | AAGGGLMSKAGSTKT HCCCCHHHCCCCCCC | 25.13 | 29688323 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PUG1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PUG1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PUG1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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