dbPTM

PABC_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PABC_YEAST
UniProt AC	Q03266
Protein Name	Aminodeoxychorismate lyase
Gene Name	ABZ2
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	374
Subcellular Localization	Cytoplasm .
Protein Description	Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate..
Protein Sequence	MSLMDNWKTDMESYDEGGLVANPNFEVLATFRYDPGFARQSASKKEIFETPDPRLGLRDEDIRQQIINEDYSSYLRVREVNSGGDLLENIQHPDAWKHDCKTIVCQRVEDMLQVIYERFFLLDEQYQRIRIALSYFKIDFSTSLNDLLKLLVENLINCKEGNSEYHEKIQKMINERQCYKMRVLVSKTGDIRIEAIPMPMEPILKLTTDYDSVSTYFIKTMLNGFLIDSTINWDVVVSSEPLNASAFTSFKTTSRDHYARARVRMQTAINNLRGSEPTSSVSQCEILFSNKSGLLMEGSITNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYLLRLGLIEEGDIDIGSLTVGNEVLLFNGVMGCIKGTVKTKY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
187	Acetylation	KMRVLVSKTGDIRIE EEEEEEECCCCEEEE	49.39	25381059

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PABC_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PABC_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PABC_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PABC_YEAST	ABZ2	physical	17873082
ATG34_YEAST	ATG34	physical	18719252
FABG_YEAST	OAR1	genetic	21623372
QCR7_YEAST	QCR7	genetic	21623372
PFKA1_YEAST	PFK1	genetic	21623372
THDH_YEAST	ILV1	genetic	21623372
DCOR_YEAST	SPE1	genetic	21623372
SLX5_YEAST	SLX5	genetic	27708008
MRM2_YEAST	MRM2	genetic	27708008
CUP2_YEAST	CUP2	genetic	27708008
YG1I_YEAST	YGR026W	genetic	27708008
MSP1_YEAST	MSP1	genetic	27708008
XKS1_YEAST	XKS1	genetic	27708008
SAY1_YEAST	SAY1	genetic	27708008
MSN1_YEAST	MSN1	genetic	27708008
ATG5_YEAST	ATG5	genetic	27708008
CHK1_YEAST	CHK1	genetic	27708008
RAD57_YEAST	RAD57	genetic	27708008
SBE2_YEAST	SBE2	genetic	27708008
RGI1_YEAST	RGI1	genetic	27708008
METE_YEAST	MET6	genetic	27708008
AIM11_YEAST	AIM11	genetic	27708008
TMN3_YEAST	TMN3	genetic	27708008
KC13_YEAST	YCK3	genetic	27708008
DDI1_YEAST	DDI1	genetic	27708008
UBP6_YEAST	UBP6	genetic	27708008
DCV1_YEAST	DCV1	genetic	27708008
ROG1_YEAST	ROG1	genetic	27708008
GTR2_YEAST	GTR2	genetic	27708008
PUS6_YEAST	PUS6	genetic	27708008
UGPA2_YEAST	YHL012W	genetic	27708008
SMF2_YEAST	SMF2	genetic	27708008
TRXB2_YEAST	TRR2	genetic	27708008
SOL1_YEAST	SOL1	genetic	27708008
YO014_YEAST	YOL014W	genetic	27708008
RTG1_YEAST	RTG1	genetic	27708008
MPD2_YEAST	MPD2	genetic	27708008
TRM11_YEAST	TRM11	genetic	27708008
YSP3_YEAST	YSP3	genetic	27708008
SKI7_YEAST	SKI7	genetic	27708008
BUD21_YEAST	BUD21	genetic	27708008
GSP2_YEAST	GSP2	genetic	27708008
PMA2_YEAST	PMA2	genetic	27708008
RL7B_YEAST	RPL7B	genetic	27708008
MDL2_YEAST	MDL2	genetic	27708008
BUD31_YEAST	BUD31	genetic	29674565
RIC1_YEAST	RIC1	genetic	29674565
SUB1_YEAST	SUB1	genetic	29674565
NAB3_YEAST	NAB3	genetic	29674565

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PABC_YEAST

Related Literatures of Post-Translational Modification