SOL1_YEAST - dbPTM
SOL1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SOL1_YEAST
UniProt AC P50278
Protein Name 6-phosphogluconolactonase-like protein 1
Gene Name SOL1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 321
Subcellular Localization Cytoplasm. Nucleus.
Protein Description May be involved in regulation of tRNA subcellular distribution..
Protein Sequence MTTTVPKVFAFHEFAGVAEAVADHVIHAQNSALKKGKVSRSTQMSGTSLNGNGNTESKTMERVNSVRSNASSRGGSEDGATKKLKKEKERRFKIALSGGSLIQVLHEGLLKRDDVQWGKWDIYFADERLVPFSSSESNYGLAKRKIFDLIDTEKYGTPKIYHIDESLINDPQECADNYEKILIKGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQENLRENLAWVIPVENAPSGPSNRISLTIPVICHSHRVTFVVEGATKAPVIKTIMERPEKGLPSSIVNEGAAGRVSWFVDDDALKDVFVIKKKYKFYDDENLTE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
39PhosphorylationALKKGKVSRSTQMSG
HHHCCCCCCCCCCCC		24.8120377248
41PhosphorylationKKGKVSRSTQMSGTS
HCCCCCCCCCCCCCC		18.5822369663
42PhosphorylationKGKVSRSTQMSGTSL
CCCCCCCCCCCCCCC		27.4720377248
45PhosphorylationVSRSTQMSGTSLNGN
CCCCCCCCCCCCCCC		29.1522369663
47PhosphorylationRSTQMSGTSLNGNGN
CCCCCCCCCCCCCCC		23.8022369663
48PhosphorylationSTQMSGTSLNGNGNT
CCCCCCCCCCCCCCC		24.3022369663
55PhosphorylationSLNGNGNTESKTMER
CCCCCCCCCCHHHHH		42.9322369663
57PhosphorylationNGNGNTESKTMERVN
CCCCCCCCHHHHHHH		31.2422369663
58UbiquitinationGNGNTESKTMERVNS
CCCCCCCHHHHHHHH		45.7323749301
59PhosphorylationNGNTESKTMERVNSV
CCCCCCHHHHHHHHH		33.2821440633
65PhosphorylationKTMERVNSVRSNASS
HHHHHHHHHHHCCCC		18.9522369663
68PhosphorylationERVNSVRSNASSRGG
HHHHHHHHCCCCCCC		34.2922369663
71PhosphorylationNSVRSNASSRGGSED
HHHHHCCCCCCCCCC		25.4822369663
72PhosphorylationSVRSNASSRGGSEDG
HHHHCCCCCCCCCCC		32.3122369663
76PhosphorylationNASSRGGSEDGATKK
CCCCCCCCCCCCCCH		35.0320377248
81PhosphorylationGGSEDGATKKLKKEK
CCCCCCCCCHHHHHH		33.9522369663
111AcetylationVLHEGLLKRDDVQWG
HHHHHHCCCCCCCCC		59.8424489116
139PhosphorylationFSSSESNYGLAKRKI
CCCCCCCCHHCCHHH		23.8523749301
143UbiquitinationESNYGLAKRKIFDLI
CCCCHHCCHHHHHHH		60.3023749301
152PhosphorylationKIFDLIDTEKYGTPK
HHHHHHCHHHHCCCC		27.6425882841
320PhosphorylationFYDDENLTE------
CCCCCCCCC------		51.7522369663
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SOL1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SOL1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SOL1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
XPOT_YEASTLOS1genetic
15454531
SOL2_YEASTSOL2physical
16554755
REG1_YEASTREG1physical
16554755
BMH2_YEASTBMH2physical
16554755
PUR91_YEASTADE16physical
16554755
PUR92_YEASTADE17physical
16554755
SLS1_YEASTSLS1genetic
19061648
PXR1_YEASTPXR1genetic
19061648
YJ9I_YEASTYJR141Wgenetic
19061648
YRB2_YEASTYRB2genetic
19061648
PRP22_YEASTPRP22genetic
19061648
CAK1_YEASTCAK1genetic
19061648
AIR2_YEASTAIR2genetic
19061648
SYF2_YEASTSYF2genetic
19061648
PRP40_YEASTPRP40genetic
19061648
TSR3_YEASTTSR3genetic
19061648
HIR2_YEASTHIR2genetic
19061648
FHL1_YEASTFHL1genetic
19061648
EAF5_YEASTEAF5genetic
19061648
GAC1_YEASTGAC1physical
18719252
PIG1_YEASTPIG1physical
18719252
BDF2_YEASTBDF2physical
18719252
KHSE_YEASTTHR1genetic
19269370
ADK_YEASTADO1genetic
19269370
CET1_YEASTCET1genetic
19269370
FHL1_YEASTFHL1genetic
19269370
HSP71_YEASTSSA1physical
19536198
SOL2_YEASTSOL2genetic
18408719
GSM1_YEASTGSM1genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
VPS41_YEASTVPS41genetic
27708008
RS27B_YEASTRPS27Bgenetic
27708008
FEN1_YEASTRAD27genetic
27708008
SAC1_YEASTSAC1genetic
27708008
GSF2_YEASTGSF2genetic
27708008
YML9_YEASTYML119Wgenetic
27708008
MIX17_YEASTMIX17genetic
27708008
RAD14_YEASTRAD14genetic
27708008
FSH2_YEASTFSH2genetic
27708008
MRE11_YEASTMRE11genetic
27708008
SFL1_YEASTSFL1genetic
27708008
DHE4_YEASTGDH1genetic
27708008
YME1_YEASTYME1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SOL1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-45; SER-48; SER-65;SER-68 AND THR-320, AND MASS SPECTROMETRY.
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65; SER-68 AND SER-71,AND MASS SPECTROMETRY.
"Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry.";
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.;
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-65, AND MASSSPECTROMETRY.
"Phosphoproteome analysis by mass spectrometry and its application toSaccharomyces cerevisiae.";
Ficarro S.B., McCleland M.L., Stukenberg P.T., Burke D.J., Ross M.M.,Shabanowitz J., Hunt D.F., White F.M.;
Nat. Biotechnol. 20:301-305(2002).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-45; SER-48; SER-65 ANDSER-68, AND MASS SPECTROMETRY.
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae.";
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.;
J. Proteome Res. 6:1190-1197(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-320, AND MASSSPECTROMETRY.
"Quantitative phosphoproteomics applied to the yeast pheromonesignaling pathway.";
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,Mann M., Jensen O.N.;
Mol. Cell. Proteomics 4:310-327(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-320, AND MASSSPECTROMETRY.

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