OPI10_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OPI10_YEAST
• UniProt AC: Q08202
• Protein Name: Protein OPI10
• Gene Name: OPI10
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 246
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Involved in phospholipid biosynthesis..
• Protein Sequence: MFAAIASGNPLQLSVEVPNSNGLQHTIVLSRTKPKLYSHITLFILPNVTFPQDYIATVYFKLSPQEEFKLFGYLSSEKPSAIFKVQIPSSKKDAGDTSDGLGEIDMDVDDGSGAADPFTDTNGSSSNNISELIIGISIEPREQGMMKLEEWKASMNAEAQKNNSLILSRPNLGIIRNITTAGQLAQVYPSLTQELAAKIVQHAYNYLSGFLDAQGNVPIKRFDTWWDKFRNRLANDGTFLDEVTKN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Phosphorylation	FKVQIPSSKKDAGDT EEEECCCCCCCCCCC	38.07	28889911
164	Phosphorylation	AEAQKNNSLILSRPN HHHHHCCCEEECCCC	26.61	28889911
228	Acetylation	RFDTWWDKFRNRLAN CCCHHHHHHHHHHHC	32.28	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OPI10_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OPI10_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OPI10_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SGF29_YEAST	SGF29	genetic	27708008
ACL4_YEAST	YDR161W	genetic	27708008
RS27B_YEAST	RPS27B	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
MDL2_YEAST	MDL2	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-164, AND MASSSPECTROMETRY.
PubMed: 18407956